Neoadjuvant pembrolizumab plus chemotherapy followed by adjuvant pembrolizumab compared with neoadjuvant chemotherapy alone in patients with early-stage non-small-cell lung cancer (KEYNOTE-671): a randomised, double-blind, placebo-controlled, phase 3 trial
- DOI
- 10.1016/s0140-6736(24)01756-2
- Published
- 2024-09
- Container
- The Lancet
- Publisher
- Elsevier BV
- Open access
- unknown
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BibTeX
@article{allodium:10.1016/s0140-6736-24-01756-2,
title = {Neoadjuvant pembrolizumab plus chemotherapy followed by adjuvant pembrolizumab compared with neoadjuvant chemotherapy alone in patients with early-stage non-small-cell lung cancer (KEYNOTE-671): a randomised, double-blind, placebo-controlled, phase 3 trial},
author = {Jonathan D Spicer and Marina C Garassino and Heather Wakelee and Moishe Liberman and Terufumi Kato and Masahiro Tsuboi and Se-Hoon Lee and Ke-Neng Chen and Christophe Dooms and Margarita Majem and Ekkehard Eigendorff and Gastón L Martinengo and Olivier Bylicki and Delvys Rodríguez-Abreu and Jamie E Chaft and Silvia Novello and Jing Yang and Ashwini Arunachalam and Steven M Keller and Ayman Samkari and Shugeng Gao and Sergey Afanasyev and Samreen Ahmed and Todd Alekshun and Gustavo Alves and Ian Anderson and Luiz Henrique Araujo and Alexander Arkhipov and Arvind Arora and Jie Bai and Paul Begin and Aleksandr Belonogov and Henri Berard and Radu Berceanu-Ion and Reyes Bernabe Caro and Igor Bondarenko and Reiner Bonnet and Joaquim Bosch Barrera and Carlos Brocca and Maciej Bryl and Alessandra Bulotta and Olivier Bylicki and Antonio Calles Blanco and Enric Carcereny and Leticia Carvalho and Cristina Cebotaru and Jamie Chaft and Veena Charu and Fabio Chaves and Jun Chen and Ke-Neng Chen and Haiquan Chen and Qixun Chen and Kevin Chen and Chi-Lu Chiang and Chao-Hua Chiu and Saulius Cicenas and Elena Ciubotaru and Tudor Ciuleanu and Ioana Ciurescu and Patrick Cobb and Corlia Coetzee and Dearbhaile Collins and Diego Cortinovis and Kimberly Costas and Dan Costin and Eduardo Henrique Cronemberger and Raymund Cuevo and Sinead Cuffe and Pedro Rafael Martins De Marchi and Tadeu de Paiva Junior and Angelo Delmonte and Ingel Demedts and Koenraad Deschepper and Josiane Dias and Christophe Dooms and Boris Duchemann and Carolina Dutra and Herbert Duvivier and Ekkehard Eigendorff and Vinicius Ernani and Martin Faehling and Luiza Faria and Alexander Fedenko and Hiran Fernando and Roberto Ferrara and Vittorio Ferrari and Gene Finley and Peter Fix and Marcos Flores and Samuel Fourie and Fabio Franke and Klaus-Peter Frohling and Muhammad Furqan and Cristian Gal and Robert Galamaga and Doina Ganea and Apar Kishor Ganti and Shugeng Gao and Marina Garassino and Ryan Gentzler and Luca Gianni and Marina Gilli and Nicolas Girard and Bojidar Goranov and Vanesa Gregorc and Alastair Greystoke and Salvatore Grisanti and Christian Grohe and Michael Guarino and Jose Luiz Guimaraes and Florian Guisier and Balazs Halmos and Zane Taysir Hammoud and Ji-Youn Han and Alinta Hegmane and Fook Yew Heng and Hidehito Horinouchi and Yoshitsugu Horio and Jian Hu and Hsu-Ching Huang and Rina Hui and Norihiko Ikeda and Salvatore Intagliata and Ingrid Iordan and Conrad Jacobs and Kirti Jain and Sushil Jain and Tao Jiang and Nina Karaseva and Terufumi Kato and Paul Kaywin and Shayma Kazmi and Roger Keresztes and Sarah Khan and Jhingook Kim and Olena Kolesnik and Oleksii Kolesnik and Jens Kollmeier and Takefumi Komiya and Michael Koontz and Yuliia Krasnohrud and Timothy Kristedja and Anna Kryzhanivska and Hiroaki Kuroda and Konstantin Laktionov and Marc Lambrechts and Susanne Lang and Adrian Langleben and Se-Hoon Lee and Markus Lehmann and Evgeny Levchenko and Oleh Levenko and Shanqing Li and Bin-Chi Liao and Moishe Liberman and Iane Lima and Geoffrey Liu and Theresa Liu-Dumlao and Giuseppe Lo Russo and Yan Yan Lou and Anna Lowczak and Alexander Luft and Shaohua Ma and Margarita Majem Tarruella and Krytsyna Makles and Gaston Martinengo and Alex Martinez Marti and Danielli Matias and Julien Mazieres and Laura Mazilu and Bertrand Mennecier and Maria Rita Migliorino and Jamal Misleh and Julian Molina and Igor Morbeck and Annette Mueller and Satoshi Muto and Ernest Nadal Alforja and Alfiya Nesterova and Wataru Nishio and Jiaxin Niu and Silvia Novello and Mary O'Brien and Steven O'Day and Francesca Ogliari and Morihito Okada and Yong Kek Pang and Viktor Paramonov and Andrea Pastor and Ireneusz Pawlak and Francovito Piantedosi and Theodore Pollock and Tony Pope and Juan Puig and Saba Radhi and Suman Rao and Chenthilmurugan Rathnasabapathy and Martin Reck and Anke Reinacher-Schick and Patricia Rich and Mathias Ritgen and Achim Rittmeyer and Elisa Roca and Delvys Rodriguez-Abreu and Paul Ruff and Igor Rybkin and Hisashi Saji and Yukinori Sakao and Ashish Sangal and Armando Santoro and Rodrigo Sardenberg and Panayiotis Savvides and Roxana Scheusan and Joan Schiller and Lana Schumacher and Monika Serke and Byoung Yong Shim and Junichi Shimizu and Yutaka Shio and Anne Sibille and Robert Siegel and Diego Signorelli and Maria Smagina and Iryna Sokur and Jonathan Spicer and Gordan Srkalovic and Laura Stampleman and Alexander Starodub and Katarzyna Stencel and Kenji Sugio and Veerle Surmont and Hiroyuki Suzuki and Jacques Tabacof and Kazuya Takamochi and Lijie Tan and Fumihiro Tanaka and Marcelo Tatangelo and Dagmar Täuscher and Carlos Teixeira and Luc Thiberville and Dmytro Trukhin and Chen-Liang Tsai and Masahiro Tsuboi and Andrei Ungureanu and Grygorii Ursol and Tonu Vanakesa and Johan Vansteenkiste and Mirta Varela and Miguel Villalona-Calero and Liza Villaruz and Gunther Vogel and Nataliia Voitko and Heather Wakelee and Qun Wang and Wenxiang Wang and Chin-Chou Wang and Sarah Wang and Thomas Wehler and Benny Weksler and Martin Wermke and Claas Wesseler and Hubert Wirtz and Mark Wong and Xiaolong Yan and Yue Yang and Kong Leong Yu and Xavier Zasadny and Marius Zemaitis and Lanjun Zhang and Guofang Zhao and Qing Zhao and Yuming Zhu and Bogdan Zurawski},
year = {2024},
journal = {The Lancet},
doi = {10.1016/s0140-6736(24)01756-2},
url = {https://doi.org/10.1016/s0140-6736(24)01756-2}
}RIS
TY - JOUR TI - Neoadjuvant pembrolizumab plus chemotherapy followed by adjuvant pembrolizumab compared with neoadjuvant chemotherapy alone in patients with early-stage non-small-cell lung cancer (KEYNOTE-671): a randomised, double-blind, placebo-controlled, phase 3 trial AU - Jonathan D Spicer AU - Marina C Garassino AU - Heather Wakelee AU - Moishe Liberman AU - Terufumi Kato AU - Masahiro Tsuboi AU - Se-Hoon Lee AU - Ke-Neng Chen AU - Christophe Dooms AU - Margarita Majem AU - Ekkehard Eigendorff AU - Gastón L Martinengo AU - Olivier Bylicki AU - Delvys Rodríguez-Abreu AU - Jamie E Chaft AU - Silvia Novello AU - Jing Yang AU - Ashwini Arunachalam AU - Steven M Keller AU - Ayman Samkari AU - Shugeng Gao AU - Sergey Afanasyev AU - Samreen Ahmed AU - Todd Alekshun AU - Gustavo Alves AU - Ian Anderson AU - Luiz Henrique Araujo AU - Alexander Arkhipov AU - Arvind Arora AU - Jie Bai AU - Paul Begin AU - Aleksandr Belonogov AU - Henri Berard AU - Radu Berceanu-Ion AU - Reyes Bernabe Caro AU - Igor Bondarenko AU - Reiner Bonnet AU - Joaquim Bosch Barrera AU - Carlos Brocca AU - Maciej Bryl AU - Alessandra Bulotta AU - Olivier Bylicki AU - Antonio Calles Blanco AU - Enric Carcereny AU - Leticia Carvalho AU - Cristina Cebotaru AU - Jamie Chaft AU - Veena Charu AU - Fabio Chaves AU - Jun Chen AU - Ke-Neng Chen AU - Haiquan Chen AU - Qixun Chen AU - Kevin Chen AU - Chi-Lu Chiang AU - Chao-Hua Chiu AU - Saulius Cicenas AU - Elena Ciubotaru AU - Tudor Ciuleanu AU - Ioana Ciurescu AU - Patrick Cobb AU - Corlia Coetzee AU - Dearbhaile Collins AU - Diego Cortinovis AU - Kimberly Costas AU - Dan Costin AU - Eduardo Henrique Cronemberger AU - Raymund Cuevo AU - Sinead Cuffe AU - Pedro Rafael Martins De Marchi AU - Tadeu de Paiva Junior AU - Angelo Delmonte AU - Ingel Demedts AU - Koenraad Deschepper AU - Josiane Dias AU - Christophe Dooms AU - Boris Duchemann AU - Carolina Dutra AU - Herbert Duvivier AU - Ekkehard Eigendorff AU - Vinicius Ernani AU - Martin Faehling AU - Luiza Faria AU - Alexander Fedenko AU - Hiran Fernando AU - Roberto Ferrara AU - Vittorio Ferrari AU - Gene Finley AU - Peter Fix AU - Marcos Flores AU - Samuel Fourie AU - Fabio Franke AU - Klaus-Peter Frohling AU - Muhammad Furqan AU - Cristian Gal AU - Robert Galamaga AU - Doina Ganea AU - Apar Kishor Ganti AU - Shugeng Gao AU - Marina Garassino AU - Ryan Gentzler AU - Luca Gianni AU - Marina Gilli AU - Nicolas Girard AU - Bojidar Goranov AU - Vanesa Gregorc AU - Alastair Greystoke AU - Salvatore Grisanti AU - Christian Grohe AU - Michael Guarino AU - Jose Luiz Guimaraes AU - Florian Guisier AU - Balazs Halmos AU - Zane Taysir Hammoud AU - Ji-Youn Han AU - Alinta Hegmane AU - Fook Yew Heng AU - Hidehito Horinouchi AU - Yoshitsugu Horio AU - Jian Hu AU - Hsu-Ching Huang AU - Rina Hui AU - Norihiko Ikeda AU - Salvatore Intagliata AU - Ingrid Iordan AU - Conrad Jacobs AU - Kirti Jain AU - Sushil Jain AU - Tao Jiang AU - Nina Karaseva AU - Terufumi Kato AU - Paul Kaywin AU - Shayma Kazmi AU - Roger Keresztes AU - Sarah Khan AU - Jhingook Kim AU - Olena Kolesnik AU - Oleksii Kolesnik AU - Jens Kollmeier AU - Takefumi Komiya AU - Michael Koontz AU - Yuliia Krasnohrud AU - Timothy Kristedja AU - Anna Kryzhanivska AU - Hiroaki Kuroda AU - Konstantin Laktionov AU - Marc Lambrechts AU - Susanne Lang AU - Adrian Langleben AU - Se-Hoon Lee AU - Markus Lehmann AU - Evgeny Levchenko AU - Oleh Levenko AU - Shanqing Li AU - Bin-Chi Liao AU - Moishe Liberman AU - Iane Lima AU - Geoffrey Liu AU - Theresa Liu-Dumlao AU - Giuseppe Lo Russo AU - Yan Yan Lou AU - Anna Lowczak AU - Alexander Luft AU - Shaohua Ma AU - Margarita Majem Tarruella AU - Krytsyna Makles AU - Gaston Martinengo AU - Alex Martinez Marti AU - Danielli Matias AU - Julien Mazieres AU - Laura Mazilu AU - Bertrand Mennecier AU - Maria Rita Migliorino AU - Jamal Misleh AU - Julian Molina AU - Igor Morbeck AU - Annette Mueller AU - Satoshi Muto AU - Ernest Nadal Alforja AU - Alfiya Nesterova AU - Wataru Nishio AU - Jiaxin Niu AU - Silvia Novello AU - Mary O'Brien AU - Steven O'Day AU - Francesca Ogliari AU - Morihito Okada AU - Yong Kek Pang AU - Viktor Paramonov AU - Andrea Pastor AU - Ireneusz Pawlak AU - Francovito Piantedosi AU - Theodore Pollock AU - Tony Pope AU - Juan Puig AU - Saba Radhi AU - Suman Rao AU - Chenthilmurugan Rathnasabapathy AU - Martin Reck AU - Anke Reinacher-Schick AU - Patricia Rich AU - Mathias Ritgen AU - Achim Rittmeyer AU - Elisa Roca AU - Delvys Rodriguez-Abreu AU - Paul Ruff AU - Igor Rybkin AU - Hisashi Saji AU - Yukinori Sakao AU - Ashish Sangal AU - Armando Santoro AU - Rodrigo Sardenberg AU - Panayiotis Savvides AU - Roxana Scheusan AU - Joan Schiller AU - Lana Schumacher AU - Monika Serke AU - Byoung Yong Shim AU - Junichi Shimizu AU - Yutaka Shio AU - Anne Sibille AU - Robert Siegel AU - Diego Signorelli AU - Maria Smagina AU - Iryna Sokur AU - Jonathan Spicer AU - Gordan Srkalovic AU - Laura Stampleman AU - Alexander Starodub AU - Katarzyna Stencel AU - Kenji Sugio AU - Veerle Surmont AU - Hiroyuki Suzuki AU - Jacques Tabacof AU - Kazuya Takamochi AU - Lijie Tan AU - Fumihiro Tanaka AU - Marcelo Tatangelo AU - Dagmar Täuscher AU - Carlos Teixeira AU - Luc Thiberville AU - Dmytro Trukhin AU - Chen-Liang Tsai AU - Masahiro Tsuboi AU - Andrei Ungureanu AU - Grygorii Ursol AU - Tonu Vanakesa AU - Johan Vansteenkiste AU - Mirta Varela AU - Miguel Villalona-Calero AU - Liza Villaruz AU - Gunther Vogel AU - Nataliia Voitko AU - Heather Wakelee AU - Qun Wang AU - Wenxiang Wang AU - Chin-Chou Wang AU - Sarah Wang AU - Thomas Wehler AU - Benny Weksler AU - Martin Wermke AU - Claas Wesseler AU - Hubert Wirtz AU - Mark Wong AU - Xiaolong Yan AU - Yue Yang AU - Kong Leong Yu AU - Xavier Zasadny AU - Marius Zemaitis AU - Lanjun Zhang AU - Guofang Zhao AU - Qing Zhao AU - Yuming Zhu AU - Bogdan Zurawski PY - 2024 JO - The Lancet DO - 10.1016/s0140-6736(24)01756-2 UR - https://doi.org/10.1016/s0140-6736(24)01756-2 ER -
APA
Spicer, J. D., Garassino, M. C., Wakelee, H., Liberman, M., Kato, T., Tsuboi, M., Lee, S., Chen, K., Dooms, C., Majem, M., Eigendorff, E., Martinengo, G. L., Bylicki, O., Rodríguez-Abreu, D., Chaft, J. E., Novello, S., Yang, J., Arunachalam, A., Keller, S. M., Samkari, A., Gao, S., Afanasyev, S., Ahmed, S., Alekshun, T., Alves, G., Anderson, I., Araujo, L. H., Arkhipov, A., Arora, A., Bai, J., Begin, P., Belonogov, A., Berard, H., Berceanu-Ion, R., Caro, R. B., Bondarenko, I., Bonnet, R., Barrera, J. B., Brocca, C., Bryl, M., Bulotta, A., Bylicki, O., Blanco, A. C., Carcereny, E., Carvalho, L., Cebotaru, C., Chaft, J., Charu, V., Chaves, F., Chen, J., Chen, K., Chen, H., Chen, Q., Chen, K., Chiang, C., Chiu, C., Cicenas, S., Ciubotaru, E., Ciuleanu, T., Ciurescu, I., Cobb, P., Coetzee, C., Collins, D., Cortinovis, D., Costas, K., Costin, D., Cronemberger, E. H., Cuevo, R., Cuffe, S., Marchi, P. R. M. D., Junior, T. D. P., Delmonte, A., Demedts, I., Deschepper, K., Dias, J., Dooms, C., Duchemann, B., Dutra, C., Duvivier, H., Eigendorff, E., Ernani, V., Faehling, M., Faria, L., Fedenko, A., Fernando, H., Ferrara, R., Ferrari, V., Finley, G., Fix, P., Flores, M., Fourie, S., Franke, F., Frohling, K., Furqan, M., Gal, C., Galamaga, R., Ganea, D., Ganti, A. K., Gao, S., Garassino, M., Gentzler, R., Gianni, L., Gilli, M., Girard, N., Goranov, B., Gregorc, V., Greystoke, A., Grisanti, S., Grohe, C., Guarino, M., Guimaraes, J. L., Guisier, F., Halmos, B., Hammoud, Z. T., Han, J., Hegmane, A., Heng, F. Y., Horinouchi, H., Horio, Y., Hu, J., Huang, H., Hui, R., Ikeda, N., Intagliata, S., Iordan, I., Jacobs, C., Jain, K., Jain, S., Jiang, T., Karaseva, N., Kato, T., Kaywin, P., Kazmi, S., Keresztes, R., Khan, S., Kim, J., Kolesnik, O., Kolesnik, O., Kollmeier, J., Komiya, T., Koontz, M., Krasnohrud, Y., Kristedja, T., Kryzhanivska, A., Kuroda, H., Laktionov, K., Lambrechts, M., Lang, S., Langleben, A., Lee, S., Lehmann, M., Levchenko, E., Levenko, O., Li, S., Liao, B., Liberman, M., Lima, I., Liu, G., Liu-Dumlao, T., Russo, G. L., Lou, Y. Y., Lowczak, A., Luft, A., Ma, S., Tarruella, M. M., Makles, K., Martinengo, G., Marti, A. M., Matias, D., Mazieres, J., Mazilu, L., Mennecier, B., Migliorino, M. R., Misleh, J., Molina, J., Morbeck, I., Mueller, A., Muto, S., Alforja, E. N., Nesterova, A., Nishio, W., Niu, J., Novello, S., O'Brien, M., O'Day, S., Ogliari, F., Okada, M., Pang, Y. K., Paramonov, V., Pastor, A., Pawlak, I., Piantedosi, F., Pollock, T., Pope, T., Puig, J., Radhi, S., Rao, S., Rathnasabapathy, C., Reck, M., Reinacher-Schick, A., Rich, P., Ritgen, M., Rittmeyer, A., Roca, E., Rodriguez-Abreu, D., Ruff, P., Rybkin, I., Saji, H., Sakao, Y., Sangal, A., Santoro, A., Sardenberg, R., Savvides, P., Scheusan, R., Schiller, J., Schumacher, L., Serke, M., Shim, B. Y., Shimizu, J., Shio, Y., Sibille, A., Siegel, R., Signorelli, D., Smagina, M., Sokur, I., Spicer, J., Srkalovic, G., Stampleman, L., Starodub, A., Stencel, K., Sugio, K., Surmont, V., Suzuki, H., Tabacof, J., Takamochi, K., Tan, L., Tanaka, F., Tatangelo, M., Täuscher, D., Teixeira, C., Thiberville, L., Trukhin, D., Tsai, C., Tsuboi, M., Ungureanu, A., Ursol, G., Vanakesa, T., Vansteenkiste, J., Varela, M., Villalona-Calero, M., Villaruz, L., Vogel, G., Voitko, N., Wakelee, H., Wang, Q., Wang, W., Wang, C., Wang, S., Wehler, T., Weksler, B., Wermke, M., Wesseler, C., Wirtz, H., Wong, M., Yan, X., Yang, Y., Yu, K. L., Zasadny, X., Zemaitis, M., Zhang, L., Zhao, G., Zhao, Q., Zhu, Y., & Zurawski, B. (2024). Neoadjuvant pembrolizumab plus chemotherapy followed by adjuvant pembrolizumab compared with neoadjuvant chemotherapy alone in patients with early-stage non-small-cell lung cancer (KEYNOTE-671): a randomised, double-blind, placebo-controlled, phase 3 trial. The Lancet. https://doi.org/10.1016/s0140-6736(24)01756-2
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- crossref · retrieved 2026-09-27T05:54:45.773Z