Optimal timing of anticoagulation after acute ischaemic stroke with atrial fibrillation (OPTIMAS): a multicentre, blinded-endpoint, phase 4, randomised controlled trial
- DOI
- 10.1016/s0140-6736(24)02197-4
- Published
- 2024-11
- Container
- The Lancet
- Publisher
- Elsevier BV
- Open access
- unknown
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BibTeX
@article{allodium:10.1016/s0140-6736-24-02197-4,
title = {Optimal timing of anticoagulation after acute ischaemic stroke with atrial fibrillation (OPTIMAS): a multicentre, blinded-endpoint, phase 4, randomised controlled trial},
author = {David J Werring and Hakim-Moulay Dehbi and Norin Ahmed and Liz Arram and Jonathan G Best and Maryam Balogun and Kate Bennett and Ekaterina Bordea and Emilia Caverly and Marisa Chau and Hannah Cohen and Mairead Cullen and Caroline J Doré and Stefan T Engelter and Robert Fenner and Gary A Ford and Aneet Gill and Rachael Hunter and Martin James and Archana Jayanthi and Gregory Y H Lip and Sue Massingham and Macey L Murray and Iwona Mazurczak and Philip S Nash and Amalia Ndoutoumou and Bo Norrving and Hannah Sims and Nikola Sprigg and Tishok Vanniyasingam and Nick Freemantle and Benjamin Jelley and Tom Hughes and Mim Evans and Diego Garcia Esteban and Lucy Knibbs and Lauren Broad and Rebecca Price and Liz Hamer Griebel and Sian Hewson and Kamy Thavanesan and Louise Mallon and Anna Smith and Miranda White and Liqun Zhang and Brian Clarke and Youssif Abousleiman and Lauren Binnie and Cai Hua Sim and Margarida Castanheira and Fiona Humphries and Sabaa Obarey and Shez Feerick and Yee Chin Lee and Alex Lewis and Riham Muhammad and Nina Francia and Ndifreke Atang and Azra Banaras and Marilena Marinescu and Philip Ferdinand and Resti Varquez and Ida Ponce and Surabhi Saxena and Eoin O'Brien and Juliana Delos Reyes and Jennifer Mitchell-Douglas and Jobbin Francis and Soma Banerjee and Vaishali Dave and Sheila Mashate and Tulsi Patel and Lakshmanan Sekaran and Wahid Murad and Asokanathan Asaipillai and Sethuraman Sakthivel and Margaret Tate and Jane Angus and Lisa Reid and Caroline Fornolles and Saul Sundayi and Lincy Poolon and Francis Justin and Sophy Hunte and Mohit Bhandari and Jules Kho and Vera Cvoro and Ruwan Parakramawansha and Mandy Couser and Hannah Hughes and Aaizza Naqvi and Kirsty Harkness and Emma Richards and Jo Howe and Chris Kamara and Jon Gardner and Harjit Bains and Rachel Teal and Jeethu Joseph and Jithen Benjamin and Samer Al-Hussayni and George Thomas and Faye Robinson and Lynn Dixon and Manju Krishnan and Peter Slade and Tal Anjum and Sharon Storton and Katja Adie and Keren Northcott and Katie Morgan and Emilie Williams and Harinath Chanashekar and Holly Maguire and Claire Gabriel and Deborah Maren and Hannah David and Sheron Clarke and Kiruba Nagaratnam and Varun Nelatur and Neelima Mannava and Lara Blasco and Joseph Devine and Rajaram Bathula and Parvathy Gopi and Niharika Mehta and Sreena Sreedevi Raj and James Teo and Laszio Sztriha and Yee Mah and Sandeep Ankolekar and Beatrix Sari and Maria Tibajai and Alicia Morgan and Maria Recaman and Samantha Bayhonan and Caroline Belo and Sharon Finch and Samantha Keenan and Angie Bowring and Ashit Shetty and Siang Chan and Lucy Gray and Thomas Harrison and Oliver Spooner and Edward Kinsella-Perks and Esther Erumere and Brittany Sanders and Don Sims and Mark Willmot and Edward Littleton and Elaine Spruce and Lisa Moody and Christopher Sheriden and Scott Luxmore-Brown and Aoife Neal and Sophie Beddows and Maria Assuncao Tuna and Amulya Misra and Ruth Penn and Sonia Mariampillai and Ijaz Anwar and Arunkumar Annamalai and Sarah Whitehouse and Lorna Shepherd and Elaine Siddle and Kausik Chatterjee and Sandra Leason and Angela Davies and Richard James Marigold and Sarah Frank and Alix Baird and Tomas Hannam-Penfold and Liliana Inacio and Simon Smith and David Eveson and Kashif Musarrat and Shagufta Khan and Tracy Harris and Muhibbur Chowdhury and Sajid Alam and Elena Jamieson and Ebitare Anyankpele and Farah Al Shalchi and Vanessa Rivers and Stephanie Bell and Rebecca Francis and Deborah Beeby and Jenny Finch and Mary Joan Macleod and German Guzman-Gutierrez and Karla Carter and Janice Irvine and Lukuman Gbadamoshi and Telma Costa and Sarah Heirons and Hayley Stoney and Louise Shaw and James Choulerton and Darwin Catibog and Naweed Sattar and Min Myint and Andy Smith and Kwin Serac and Hedley Emsley and Sulaiman Sultan and Bindu Gregary and Allan Brown and Afzal Mahmood and Navraj Chattha and William Old and Claire Pegg and Miriam Davey and Michelle Page and Banher Sandhu and Emily Phiri and Khalid Rashed and Elisabeth Wilson and Esther Hindley and Sarah Board and Sherly Antony and Alfonso Tanate and Michelle Davis and Beth Holland and Victoria Slater and Michelle Fawcett and Tim England and James Scott and Jessica Beavan and Amanda Hedstrom and Dumin Karunatilake and Kimberley Gillmain and Nishy Singh and Tracy Hallows and Mark Barber and Luke Yates and Clayton Micallef and Derek Esson and Wai Meng Yu and Benjamin Jaa Ming New and Alexandre Matos and Clare Burt and Louise Cabrelli and Gillian Wilkie and Madana Meegada and Ramanathan Kirthivasan and Caroline Fox and Victoria Mead and Amanda Lyle and Rajesh Saksena and Aashima Bakshi and Alison O'Kelly and Jahanzeb Rehan and Osaretin Ebueka and Martin Cooper and Inez Wynter and Susan Smith and Senthil Kumar and Linda O'Brien and Cerrys Parker and Emma Parker and Numan Khan and Christopher Patterson and Stuart Maguire and Outi Quinn and Ruth Bellfield and Yousif Behnam and Janet Costa and Cheryl Padilla-Harris and Louise Moram and Syed Abid Raza and Helen Tench and Tanya Sims and Heather McGuinness and Ronda Loosley and Rebecca Wolf-Roberts and Sandeep Buddha and Irmak Salt and Kerry Lewis and Sunanda Mavinamne and Coleen Ditchfield and Sharon Dealing and Alexander Shah and Ginette Crossingham and Memory Mwadeyi and Anthony Kenton and Faith Omoregie and Saidu Abubakar and Allison Warwick and Gemma Hector and Ahamad Hassan and Emelda Veraque and Michelle Farman and Linetty Makawa and Anthony Byrne and Jackie Kirkham and Gareth Blayney and Jey Selwyn and Puneet Kakar and Mohammed Al Khaddour and Reena Dhami and Emelda Baker and Bernard Esisi and Emma Clarkson and Dominic Fellowes and Jergovic Kresmir and Paul Guyler and David Ngo and Indunil Wijenayake and Sharon Tysoe and Joanne Galliford and Paula Harman and Mark Garside and Madhava Badanahatti and Anna Smith and Victoria Riddell and Gita Gramizadeh and Dipankar Dutta and Milda Bajoriene and Hulya Erdogan and Deborah Ward and Fergus Doubal and Neshika Samarasekera and Sarah Risbridger and Allan MacRaild and Abul Azim and Lisa Wood and Ruth Tampset and Raj Shekhar and Umesh Rai and Tracy Fuller and Aricsa Joshy and Evelyn Nadar and Manohar Kini and Syed Ahmad and Matthew Robinson and Lucia King and Venkatesan Srinivasan and Magdalena Karwacka-Cichomska and Vicki Moore and Kate Smith and Bincy Kariyadil and Kelvin Kong and Kelly Hubbard and Sarwat Arif and Muhammad Hasan and Natalie Temple and Daniele Arcoria and Zoey Horne and Thandar Soe and Hilary Wyllie and Christian Hacon and Helen Sutherland and Brian Menezes and Venetia Johnson and Nigel Smyth and Zehra Mehdi and Ela Tone and Arian Bradley and Emma Levell and Aleksandra Ekkert and Sara Mazzucco and Laura McCafferty and Linda Vonoven and Suprita Dewan and Pagadala Sridhar and Jayne Thomas and Samantha Coetzee and Becky Icke and Jill Williams and Narayanamoorthi Saravanan and Pamela Bradley and Rebecca Marie Gibson and Jijimol Antony and Imran Ashraf and Jose Mabuti and Charlotte Kamundi and Prasanna Patiola and Naomi Oakley and Harold Proeschel and Debs Kelly and Wendy Longley and Ashleigh Cave and Carla Ambrico and Toby Black and Elisa Porretta and Alpha Anthony and Suzanne Ragab and Judith Dube and Shahid Kausar and Abdullah Gujjar and Mohammad Abdullah and Daljit Kaur and Naveen Gadapa and Sumita Choudhary and Nabeela Nisar and Grace Fawehinmi and Karen Dunne and Sam King and Amit Kishore and Stephanie Lee and Tracy Marsden and Melanie Slaughter and Kathryn Cawley and Jane Perez and Peter Anderton and Salem Soussi and Deborah Walstow and Rebecca Pugh and Aravind Manoj and Glynn Fletcher and Paula Lopez and Michael McCormick and Michael Magee and Grainne Tallon and Denise McFarland and Denise Cosgrove and Naval Shinh and Kneale Metcalf and Alina Kostyuk and Susan McDonald and Sophie Sayers and Walee Sayed and Sam Abraham and Gemma Szabo and Gareth Crosbie and Jim McIlmoyle and Patricia Fearon and Kerry Courtney and Suzanne Tauro and Arun Singh and Anand Nair and Stephen Duberley and Sheeba Philip and Cath Curley and Wendy Goddard and Luke Bridge and Paul Willcoxson and Peter Wanklyn and Jennifer Owen and John France and Bryony Reed and Angie Foulds and Bella Richard and Louise Parfitt and Brendan Affley and Cristina Russo and Margaret Dsouza and Elizabeth Cruddas and David Hargroves and James Rand and Som Shekar and Yaqoob Bhat and Gail Marshall and Maxine Nash and Nasar Ahmad and Blessing Oduh Okoko and Rachel Evans and Tegan Taylor and Jesse Dawson and Elizabeth Colquhoun and Christopher James and Carlos Aguirre and Catherine MacPhee and Janet Phipps and Sissi Ispoglou and Anne Hayes and Rachel Evans},
year = {2024},
journal = {The Lancet},
doi = {10.1016/s0140-6736(24)02197-4},
url = {https://doi.org/10.1016/s0140-6736(24)02197-4}
}RIS
TY - JOUR TI - Optimal timing of anticoagulation after acute ischaemic stroke with atrial fibrillation (OPTIMAS): a multicentre, blinded-endpoint, phase 4, randomised controlled trial AU - David J Werring AU - Hakim-Moulay Dehbi AU - Norin Ahmed AU - Liz Arram AU - Jonathan G Best AU - Maryam Balogun AU - Kate Bennett AU - Ekaterina Bordea AU - Emilia Caverly AU - Marisa Chau AU - Hannah Cohen AU - Mairead Cullen AU - Caroline J Doré AU - Stefan T Engelter AU - Robert Fenner AU - Gary A Ford AU - Aneet Gill AU - Rachael Hunter AU - Martin James AU - Archana Jayanthi AU - Gregory Y H Lip AU - Sue Massingham AU - Macey L Murray AU - Iwona Mazurczak AU - Philip S Nash AU - Amalia Ndoutoumou AU - Bo Norrving AU - Hannah Sims AU - Nikola Sprigg AU - Tishok Vanniyasingam AU - Nick Freemantle AU - Benjamin Jelley AU - Tom Hughes AU - Mim Evans AU - Diego Garcia Esteban AU - Lucy Knibbs AU - Lauren Broad AU - Rebecca Price AU - Liz Hamer Griebel AU - Sian Hewson AU - Kamy Thavanesan AU - Louise Mallon AU - Anna Smith AU - Miranda White AU - Liqun Zhang AU - Brian Clarke AU - Youssif Abousleiman AU - Lauren Binnie AU - Cai Hua Sim AU - Margarida Castanheira AU - Fiona Humphries AU - Sabaa Obarey AU - Shez Feerick AU - Yee Chin Lee AU - Alex Lewis AU - Riham Muhammad AU - Nina Francia AU - Ndifreke Atang AU - Azra Banaras AU - Marilena Marinescu AU - Philip Ferdinand AU - Resti Varquez AU - Ida Ponce AU - Surabhi Saxena AU - Eoin O'Brien AU - Juliana Delos Reyes AU - Jennifer Mitchell-Douglas AU - Jobbin Francis AU - Soma Banerjee AU - Vaishali Dave AU - Sheila Mashate AU - Tulsi Patel AU - Lakshmanan Sekaran AU - Wahid Murad AU - Asokanathan Asaipillai AU - Sethuraman Sakthivel AU - Margaret Tate AU - Jane Angus AU - Lisa Reid AU - Caroline Fornolles AU - Saul Sundayi AU - Lincy Poolon AU - Francis Justin AU - Sophy Hunte AU - Mohit Bhandari AU - Jules Kho AU - Vera Cvoro AU - Ruwan Parakramawansha AU - Mandy Couser AU - Hannah Hughes AU - Aaizza Naqvi AU - Kirsty Harkness AU - Emma Richards AU - Jo Howe AU - Chris Kamara AU - Jon Gardner AU - Harjit Bains AU - Rachel Teal AU - Jeethu Joseph AU - Jithen Benjamin AU - Samer Al-Hussayni AU - George Thomas AU - Faye Robinson AU - Lynn Dixon AU - Manju Krishnan AU - Peter Slade AU - Tal Anjum AU - Sharon Storton AU - Katja Adie AU - Keren Northcott AU - Katie Morgan AU - Emilie Williams AU - Harinath Chanashekar AU - Holly Maguire AU - Claire Gabriel AU - Deborah Maren AU - Hannah David AU - Sheron Clarke AU - Kiruba Nagaratnam AU - Varun Nelatur AU - Neelima Mannava AU - Lara Blasco AU - Joseph Devine AU - Rajaram Bathula AU - Parvathy Gopi AU - Niharika Mehta AU - Sreena Sreedevi Raj AU - James Teo AU - Laszio Sztriha AU - Yee Mah AU - Sandeep Ankolekar AU - Beatrix Sari AU - Maria Tibajai AU - Alicia Morgan AU - Maria Recaman AU - Samantha Bayhonan AU - Caroline Belo AU - Sharon Finch AU - Samantha Keenan AU - Angie Bowring AU - Ashit Shetty AU - Siang Chan AU - Lucy Gray AU - Thomas Harrison AU - Oliver Spooner AU - Edward Kinsella-Perks AU - 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Kathryn Cawley AU - Jane Perez AU - Peter Anderton AU - Salem Soussi AU - Deborah Walstow AU - Rebecca Pugh AU - Aravind Manoj AU - Glynn Fletcher AU - Paula Lopez AU - Michael McCormick AU - Michael Magee AU - Grainne Tallon AU - Denise McFarland AU - Denise Cosgrove AU - Naval Shinh AU - Kneale Metcalf AU - Alina Kostyuk AU - Susan McDonald AU - Sophie Sayers AU - Walee Sayed AU - Sam Abraham AU - Gemma Szabo AU - Gareth Crosbie AU - Jim McIlmoyle AU - Patricia Fearon AU - Kerry Courtney AU - Suzanne Tauro AU - Arun Singh AU - Anand Nair AU - Stephen Duberley AU - Sheeba Philip AU - Cath Curley AU - Wendy Goddard AU - Luke Bridge AU - Paul Willcoxson AU - Peter Wanklyn AU - Jennifer Owen AU - John France AU - Bryony Reed AU - Angie Foulds AU - Bella Richard AU - Louise Parfitt AU - Brendan Affley AU - Cristina Russo AU - Margaret Dsouza AU - Elizabeth Cruddas AU - David Hargroves AU - James Rand AU - Som Shekar AU - Yaqoob Bhat AU - Gail Marshall AU - Maxine Nash AU - Nasar Ahmad AU - Blessing Oduh Okoko AU - Rachel Evans AU - Tegan Taylor AU - Jesse Dawson AU - Elizabeth Colquhoun AU - Christopher James AU - Carlos Aguirre AU - Catherine MacPhee AU - Janet Phipps AU - Sissi Ispoglou AU - Anne Hayes AU - Rachel Evans PY - 2024 JO - The Lancet DO - 10.1016/s0140-6736(24)02197-4 UR - https://doi.org/10.1016/s0140-6736(24)02197-4 ER -
APA
Werring, D. J., Dehbi, H., Ahmed, N., Arram, L., Best, J. G., Balogun, M., Bennett, K., Bordea, E., Caverly, E., Chau, M., Cohen, H., Cullen, M., Doré, C. J., Engelter, S. T., Fenner, R., Ford, G. A., Gill, A., Hunter, R., James, M., Jayanthi, A., Lip, G. Y. H., Massingham, S., Murray, M. L., Mazurczak, I., Nash, P. S., Ndoutoumou, A., Norrving, B., Sims, H., Sprigg, N., Vanniyasingam, T., Freemantle, N., Jelley, B., Hughes, T., Evans, M., Esteban, D. G., Knibbs, L., Broad, L., Price, R., Griebel, L. H., Hewson, S., Thavanesan, K., Mallon, L., Smith, A., White, M., Zhang, L., Clarke, B., Abousleiman, Y., Binnie, L., Sim, C. H., Castanheira, M., Humphries, F., Obarey, S., Feerick, S., Lee, Y. C., Lewis, A., Muhammad, R., Francia, N., Atang, N., Banaras, A., Marinescu, M., Ferdinand, P., Varquez, R., Ponce, I., Saxena, S., O'Brien, E., Reyes, J. D., Mitchell-Douglas, J., Francis, J., Banerjee, S., Dave, V., Mashate, S., Patel, T., Sekaran, L., Murad, W., Asaipillai, A., Sakthivel, S., Tate, M., Angus, J., Reid, L., Fornolles, C., Sundayi, S., Poolon, L., Justin, F., Hunte, S., Bhandari, M., Kho, J., Cvoro, V., Parakramawansha, R., Couser, M., Hughes, H., Naqvi, A., Harkness, K., Richards, E., Howe, J., Kamara, C., Gardner, J., Bains, H., Teal, R., Joseph, J., Benjamin, J., Al-Hussayni, S., Thomas, G., Robinson, F., Dixon, L., Krishnan, M., Slade, P., Anjum, T., Storton, S., Adie, K., Northcott, K., Morgan, K., Williams, E., Chanashekar, H., Maguire, H., Gabriel, C., Maren, D., David, H., Clarke, S., Nagaratnam, K., Nelatur, V., Mannava, N., Blasco, L., Devine, J., Bathula, R., Gopi, P., Mehta, N., Raj, S. S., Teo, J., Sztriha, L., Mah, Y., Ankolekar, S., Sari, B., Tibajai, M., Morgan, A., Recaman, M., Bayhonan, S., Belo, C., Finch, S., Keenan, S., Bowring, A., Shetty, A., Chan, S., Gray, L., Harrison, T., Spooner, O., Kinsella-Perks, E., Erumere, E., Sanders, B., Sims, D., Willmot, M., Littleton, E., Spruce, E., Moody, L., Sheriden, C., Luxmore-Brown, S., Neal, A., Beddows, S., Tuna, M. A., Misra, A., Penn, R., Mariampillai, S., Anwar, I., Annamalai, A., Whitehouse, S., Shepherd, L., Siddle, E., Chatterjee, K., Leason, S., Davies, A., Marigold, R. J., Frank, S., Baird, A., Hannam-Penfold, T., Inacio, L., Smith, S., Eveson, D., Musarrat, K., Khan, S., Harris, T., Chowdhury, M., Alam, S., Jamieson, E., Anyankpele, E., Shalchi, F. A., Rivers, V., Bell, S., Francis, R., Beeby, D., Finch, J., Macleod, M. J., Guzman-Gutierrez, G., Carter, K., Irvine, J., Gbadamoshi, L., Costa, T., Heirons, S., Stoney, H., Shaw, L., Choulerton, J., Catibog, D., Sattar, N., Myint, M., Smith, A., Serac, K., Emsley, H., Sultan, S., Gregary, B., Brown, A., Mahmood, A., Chattha, N., Old, W., Pegg, C., Davey, M., Page, M., Sandhu, B., Phiri, E., Rashed, K., Wilson, E., Hindley, E., Board, S., Antony, S., Tanate, A., Davis, M., Holland, B., Slater, V., Fawcett, M., England, T., Scott, J., Beavan, J., Hedstrom, A., Karunatilake, D., Gillmain, K., Singh, N., Hallows, T., Barber, M., Yates, L., Micallef, C., Esson, D., Yu, W. M., New, B. J. M., Matos, A., Burt, C., Cabrelli, L., Wilkie, G., Meegada, M., Kirthivasan, R., Fox, C., Mead, V., Lyle, A., Saksena, R., Bakshi, A., O'Kelly, A., Rehan, J., Ebueka, O., Cooper, M., Wynter, I., Smith, S., Kumar, S., O'Brien, L., Parker, C., Parker, E., Khan, N., Patterson, C., Maguire, S., Quinn, O., Bellfield, R., Behnam, Y., Costa, J., Padilla-Harris, C., Moram, L., Raza, S. A., Tench, H., Sims, T., McGuinness, H., Loosley, R., Wolf-Roberts, R., Buddha, S., Salt, I., Lewis, K., Mavinamne, S., Ditchfield, C., Dealing, S., Shah, A., Crossingham, G., Mwadeyi, M., Kenton, A., Omoregie, F., Abubakar, S., Warwick, A., Hector, G., Hassan, A., Veraque, E., Farman, M., Makawa, L., Byrne, A., Kirkham, J., Blayney, G., Selwyn, J., Kakar, P., Khaddour, M. A., Dhami, R., Baker, E., Esisi, B., Clarkson, E., Fellowes, D., Kresmir, J., Guyler, P., Ngo, D., Wijenayake, I., Tysoe, S., Galliford, J., Harman, P., Garside, M., Badanahatti, M., Smith, A., Riddell, V., Gramizadeh, G., Dutta, D., Bajoriene, M., Erdogan, H., Ward, D., Doubal, F., Samarasekera, N., Risbridger, S., MacRaild, A., Azim, A., Wood, L., Tampset, R., Shekhar, R., Rai, U., Fuller, T., Joshy, A., Nadar, E., Kini, M., Ahmad, S., Robinson, M., King, L., Srinivasan, V., Karwacka-Cichomska, M., Moore, V., Smith, K., Kariyadil, B., Kong, K., Hubbard, K., Arif, S., Hasan, M., Temple, N., Arcoria, D., Horne, Z., Soe, T., Wyllie, H., Hacon, C., Sutherland, H., Menezes, B., Johnson, V., Smyth, N., Mehdi, Z., Tone, E., Bradley, A., Levell, E., Ekkert, A., Mazzucco, S., McCafferty, L., Vonoven, L., Dewan, S., Sridhar, P., Thomas, J., Coetzee, S., Icke, B., Williams, J., Saravanan, N., Bradley, P., Gibson, R. 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- crossref · retrieved 2026-09-25T23:10:54.400Z