Efficacy and safety of nerinetide in acute ischaemic stroke in patients undergoing endovascular thrombectomy without previous thrombolysis (ESCAPE-NEXT): a multicentre, double-blind, randomised controlled trial.

Hill MD, Goyal M, Demchuk AM, Menon BK, Field TS, Guest WC, Berrouschot J, Bormann A, Pham M, Haeusler KG, Dippel DWJ, van Doormaal PJ, Dorn F, Bode FJ, van Adel BA, Sahlas DJ, Swartz RH, Da Costa L, Ospel JM, McDonough RV, Ryckborst KJ, Almekhlafi MA, Heard KJ, Garman DJ, Adams C, Kohli Y, Schoon BA, Buck BH, Muto M, Zafar A, Schneider H, Grossberg JA, Yeo LLL, Tarpley JW, Psychogios MN, Coutinho JM, Limbucci N, Puetz V, Kelly ME, Campbell BCV, Poli S, Poppe AY, Shankar JJ, Chandra R, Dowlatshahi D, Lopez GA, Cirillo L, Moussaddy A, Devlin M, Garcia-Bermejo P, Mandzia JL, Skjelland M, Aamodt AH, Silver FL, Kleinig TJ, Pero G, Minnerup J, McTaggart RA, Puri AS, Chiu AHY, Reimann G, Gubitz GJ, Camden MC, Lee SK, Sauvageau E, Mundiyanapurath S, Frei DF, Choe H, Rocha M, Gralla J, Bailey P, Fischer S, Liebig T, Dimitriadis K, Gandhi D, Chapot R, Jin A, Hassan AE, Zwam WV, Maier IL, Wiesmann M, Niesen WD, Advani R, Eltoft A, Asdaghi N, Murphy C, Remonda L, Ghia D, Jansen O, Holtmannspoetter M, Hellstern V, Witt K, Fromme A, Nimjee SM, Turkel-Parella D, Michalski D, Maegerlein C, Tham CH, Tymianski M, ESCAPE-NEXT Investigators

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DOI: 10.1016/s0140-6736(25)00194-1
Published: 2025 Feb 15
Container: Lancet (London, England)
Publisher: Not recorded
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1016/s0140-6736-25-00194-1,
  title = {Efficacy and safety of nerinetide in acute ischaemic stroke in patients undergoing endovascular thrombectomy without previous thrombolysis (ESCAPE-NEXT): a multicentre, double-blind, randomised controlled trial.},
  author = {Hill MD and Goyal M and Demchuk AM and Menon BK and Field TS and Guest WC and Berrouschot J and Bormann A and Pham M and Haeusler KG and Dippel DWJ and van Doormaal PJ and Dorn F and Bode FJ and van Adel BA and Sahlas DJ and Swartz RH and Da Costa L and Ospel JM and McDonough RV and Ryckborst KJ and Almekhlafi MA and Heard KJ and Garman DJ and Adams C and Kohli Y and Schoon BA and Buck BH and Muto M and Zafar A and Schneider H and Grossberg JA and Yeo LLL and Tarpley JW and Psychogios MN and Coutinho JM and Limbucci N and Puetz V and Kelly ME and Campbell BCV and Poli S and Poppe AY and Shankar JJ and Chandra R and Dowlatshahi D and Lopez GA and Cirillo L and Moussaddy A and Devlin M and Garcia-Bermejo P and Mandzia JL and Skjelland M and Aamodt AH and Silver FL and Kleinig TJ and Pero G and Minnerup J and McTaggart RA and Puri AS and Chiu AHY and Reimann G and Gubitz GJ and Camden MC and Lee SK and Sauvageau E and Mundiyanapurath S and Frei DF and Choe H and Rocha M and Gralla J and Bailey P and Fischer S and Liebig T and Dimitriadis K and Gandhi D and Chapot R and Jin A and Hassan AE and Zwam WV and Maier IL and Wiesmann M and Niesen WD and Advani R and Eltoft A and Asdaghi N and Murphy C and Remonda L and Ghia D and Jansen O and Holtmannspoetter M and Hellstern V and Witt K and Fromme A and Nimjee SM and Turkel-Parella D and Michalski D and Maegerlein C and Tham CH and Tymianski M and ESCAPE-NEXT Investigators},
  year = {2025},
  journal = {Lancet (London, England)},
  doi = {10.1016/s0140-6736(25)00194-1},
  url = {https://doi.org/10.1016/s0140-6736(25)00194-1}
}

RIS

TY  - JOUR
TI  - Efficacy and safety of nerinetide in acute ischaemic stroke in patients undergoing endovascular thrombectomy without previous thrombolysis (ESCAPE-NEXT): a multicentre, double-blind, randomised controlled trial.
AU  - Hill MD
AU  - Goyal M
AU  - Demchuk AM
AU  - Menon BK
AU  - Field TS
AU  - Guest WC
AU  - Berrouschot J
AU  - Bormann A
AU  - Pham M
AU  - Haeusler KG
AU  - Dippel DWJ
AU  - van Doormaal PJ
AU  - Dorn F
AU  - Bode FJ
AU  - van Adel BA
AU  - Sahlas DJ
AU  - Swartz RH
AU  - Da Costa L
AU  - Ospel JM
AU  - McDonough RV
AU  - Ryckborst KJ
AU  - Almekhlafi MA
AU  - Heard KJ
AU  - Garman DJ
AU  - Adams C
AU  - Kohli Y
AU  - Schoon BA
AU  - Buck BH
AU  - Muto M
AU  - Zafar A
AU  - Schneider H
AU  - Grossberg JA
AU  - Yeo LLL
AU  - Tarpley JW
AU  - Psychogios MN
AU  - Coutinho JM
AU  - Limbucci N
AU  - Puetz V
AU  - Kelly ME
AU  - Campbell BCV
AU  - Poli S
AU  - Poppe AY
AU  - Shankar JJ
AU  - Chandra R
AU  - Dowlatshahi D
AU  - Lopez GA
AU  - Cirillo L
AU  - Moussaddy A
AU  - Devlin M
AU  - Garcia-Bermejo P
AU  - Mandzia JL
AU  - Skjelland M
AU  - Aamodt AH
AU  - Silver FL
AU  - Kleinig TJ
AU  - Pero G
AU  - Minnerup J
AU  - McTaggart RA
AU  - Puri AS
AU  - Chiu AHY
AU  - Reimann G
AU  - Gubitz GJ
AU  - Camden MC
AU  - Lee SK
AU  - Sauvageau E
AU  - Mundiyanapurath S
AU  - Frei DF
AU  - Choe H
AU  - Rocha M
AU  - Gralla J
AU  - Bailey P
AU  - Fischer S
AU  - Liebig T
AU  - Dimitriadis K
AU  - Gandhi D
AU  - Chapot R
AU  - Jin A
AU  - Hassan AE
AU  - Zwam WV
AU  - Maier IL
AU  - Wiesmann M
AU  - Niesen WD
AU  - Advani R
AU  - Eltoft A
AU  - Asdaghi N
AU  - Murphy C
AU  - Remonda L
AU  - Ghia D
AU  - Jansen O
AU  - Holtmannspoetter M
AU  - Hellstern V
AU  - Witt K
AU  - Fromme A
AU  - Nimjee SM
AU  - Turkel-Parella D
AU  - Michalski D
AU  - Maegerlein C
AU  - Tham CH
AU  - Tymianski M
AU  - ESCAPE-NEXT Investigators
PY  - 2025
JO  - Lancet (London, England)
DO  - 10.1016/s0140-6736(25)00194-1
UR  - https://doi.org/10.1016/s0140-6736(25)00194-1
ER  -

APA

MD, H., M, G., AM, D., BK, M., TS, F., WC, G., J, B., A, B., M, P., KG, H., DWJ, D., PJ, V. D., F, D., FJ, B., BA, V. A., DJ, S., RH, S., L, D. C., JM, O., RV, M., KJ, R., MA, A., KJ, H., DJ, G., C, A., Y, K., BA, S., BH, B., M, M., A, Z., H, S., JA, G., LLL, Y., JW, T., MN, P., JM, C., N, L., V, P., ME, K., BCV, C., S, P., AY, P., JJ, S., R, C., D, D., GA, L., L, C., A, M., M, D., P, G., JL, M., M, S., AH, A., FL, S., TJ, K., G, P., J, M., RA, M., AS, P., AHY, C., G, R., GJ, G., MC, C., SK, L., E, S., S, M., DF, F., H, C., M, R., J, G., P, B., S, F., T, L., K, D., D, G., R, C., A, J., AE, H., WV, Z., IL, M., M, W., WD, N., R, A., A, E., N, A., C, M., L, R., D, G., O, J., M, H., V, H., K, W., A, F., SM, N., D, T., D, M., C, M., CH, T., M, T., & Investigators, E. (2025). Efficacy and safety of nerinetide in acute ischaemic stroke in patients undergoing endovascular thrombectomy without previous thrombolysis (ESCAPE-NEXT): a multicentre, double-blind, randomised controlled trial.. Lancet (London, England). https://doi.org/10.1016/s0140-6736(25)00194-1

Source records

pubmed · retrieved 2026-09-26T08:54:52.216Z