Pharmacological blood-pressure lowering for the prevention of cardiovascular disease and death across the full spectrum of chronic kidney disease severity: an individual-participant data meta-analysis

Guyu Zeng, Zeinab Bidel, Qianqian Yang, Dexter Canoy, Mark Woodward, Julia Lewis, Sverre E Kjeldsen, William C Cushman, Jinqing Yuan, Koon Teo, Barry R Davis, John Chalmers, Carl J Pepine, Kazem Rahimi, Milad Nazarzadeh, Amanda Adler, Larry Agodoa, Ale Algra, Craig Anderson, Folkert W Asselbergs, Colin Baigent, Nigel S Beckett, Eivind Berge, Henry Black, Eric Boersma, Barry Morton Brenner, Frank P J Brouwers, Morris Brown, Jasper J Brugts, Christopher J Bulpitt, Robert P Byington, John Chalmers, Rory Collins, Jeffrey Cutler, Barry R Davis, Richard B Devereaux, Jamie P Dwyer, Ray Estacio, Robert Fagard, Kim Fox, Tsuguya Fukui, Wiek H van Gilst, Ajay K Gupta, Rury R Holman, Yutaka Imai, Masao Ishii, Stevo Julius, Yoshihiko Kanno, Sverre E Kjeldsen, John Kostis, Kizuku Kuramoto, Jan Lanke, Edmund Lewis, Julia B Lewis, Michel Lievre, Lars H Lindholm, Jacobus Lubsen, Stephan Lueders, Stephen MacMahon, Ettore Malacco, Giuseppe Mancia, Masunori Matsuzaki, Richard J McManus, Maria H Mehlum, Bruce Neal, Steven Nissen, Hiroshi Ogawa, Toshio Ogihara, Takayoshi Ohkubo, Christopher R Palmer, Anushka Patel, Carl J Pepine, Vlado Perkovic, Marc Allan Pfeffer, Bertram Pitt, Neil R Poulter, Hiromi Rakugi, Gianpaolo Reboldi, Christopher Reid, Giuseppe Remuzzi, Anthony Rodgers, Peter Rothwell, Piero Ruggenenti, Gholamreza Salimi-Khorshidi, Takao Saruta, Joachim Schrader, Robert Schrier, Peter Sever, Peter Sleight, Jan A Staessen, Johan Sundström, Hiromichi Suzuki, Lutgarde Thijs, Fiona Turnbull, Kenji Ueshima, Seiji Umemoto, Paolo Verdecchia, Giancarlo Viberti, Kristian Wachtell, Jiguang Wang, Paul Whelton, Lindon Wing, Yoshiki Yui, Salim Yusuf, Alberto Zanchetti, Dick de Zeeuw, Zhen-Yu Zhang

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DOI: 10.1016/s0140-6736(26)00367-3
Published: 2026-04
Container: The Lancet
Publisher: Elsevier BV
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1016/s0140-6736-26-00367-3,
  title = {Pharmacological blood-pressure lowering for the prevention of cardiovascular disease and death across the full spectrum of chronic kidney disease severity: an individual-participant data meta-analysis},
  author = {Guyu Zeng and Zeinab Bidel and Qianqian Yang and Dexter Canoy and Mark Woodward and Julia Lewis and Sverre E Kjeldsen and William C Cushman and Jinqing Yuan and Koon Teo and Barry R Davis and John Chalmers and Carl J Pepine and Kazem Rahimi and Milad Nazarzadeh and Amanda Adler and Larry Agodoa and Ale Algra and Craig Anderson and Folkert W Asselbergs and Colin Baigent and Nigel S Beckett and Eivind Berge and Henry Black and Eric Boersma and Barry Morton Brenner and Frank P J Brouwers and Morris Brown and Jasper J Brugts and Christopher J Bulpitt and Robert P Byington and John Chalmers and Rory Collins and Jeffrey Cutler and Barry R Davis and Richard B Devereaux and Jamie P Dwyer and Ray Estacio and Robert Fagard and Kim Fox and Tsuguya Fukui and Wiek H van Gilst and Ajay K Gupta and Rury R Holman and Yutaka Imai and Masao Ishii and Stevo Julius and Yoshihiko Kanno and Sverre E Kjeldsen and John Kostis and Kizuku Kuramoto and Jan Lanke and Edmund Lewis and Julia B Lewis and Michel Lievre and Lars H Lindholm and Jacobus Lubsen and Stephan Lueders and Stephen MacMahon and Ettore Malacco and Giuseppe Mancia and Masunori Matsuzaki and Richard J McManus and Maria H Mehlum and Bruce Neal and Steven Nissen and Hiroshi Ogawa and Toshio Ogihara and Takayoshi Ohkubo and Christopher R Palmer and Anushka Patel and Carl J Pepine and Vlado Perkovic and Marc Allan Pfeffer and Bertram Pitt and Neil R Poulter and Hiromi Rakugi and Gianpaolo Reboldi and Christopher Reid and Giuseppe Remuzzi and Anthony Rodgers and Peter Rothwell and Piero Ruggenenti and Gholamreza Salimi-Khorshidi and Takao Saruta and Joachim Schrader and Robert Schrier and Peter Sever and Peter Sleight and Jan A Staessen and Johan Sundström and Hiromichi Suzuki and Lutgarde Thijs and Fiona Turnbull and Kenji Ueshima and Seiji Umemoto and Paolo Verdecchia and Giancarlo Viberti and Kristian Wachtell and Jiguang Wang and Paul Whelton and Lindon Wing and Yoshiki Yui and Salim Yusuf and Alberto Zanchetti and Dick de Zeeuw and Zhen-Yu Zhang},
  year = {2026},
  journal = {The Lancet},
  doi = {10.1016/s0140-6736(26)00367-3},
  url = {https://doi.org/10.1016/s0140-6736(26)00367-3}
}

RIS

TY  - JOUR
TI  - Pharmacological blood-pressure lowering for the prevention of cardiovascular disease and death across the full spectrum of chronic kidney disease severity: an individual-participant data meta-analysis
AU  - Guyu Zeng
AU  - Zeinab Bidel
AU  - Qianqian Yang
AU  - Dexter Canoy
AU  - Mark Woodward
AU  - Julia Lewis
AU  - Sverre E Kjeldsen
AU  - William C Cushman
AU  - Jinqing Yuan
AU  - Koon Teo
AU  - Barry R Davis
AU  - John Chalmers
AU  - Carl J Pepine
AU  - Kazem Rahimi
AU  - Milad Nazarzadeh
AU  - Amanda Adler
AU  - Larry Agodoa
AU  - Ale Algra
AU  - Craig Anderson
AU  - Folkert W Asselbergs
AU  - Colin Baigent
AU  - Nigel S Beckett
AU  - Eivind Berge
AU  - Henry Black
AU  - Eric Boersma
AU  - Barry Morton Brenner
AU  - Frank P J Brouwers
AU  - Morris Brown
AU  - Jasper J Brugts
AU  - Christopher J Bulpitt
AU  - Robert P Byington
AU  - John Chalmers
AU  - Rory Collins
AU  - Jeffrey Cutler
AU  - Barry R Davis
AU  - Richard B Devereaux
AU  - Jamie P Dwyer
AU  - Ray Estacio
AU  - Robert Fagard
AU  - Kim Fox
AU  - Tsuguya Fukui
AU  - Wiek H van Gilst
AU  - Ajay K Gupta
AU  - Rury R Holman
AU  - Yutaka Imai
AU  - Masao Ishii
AU  - Stevo Julius
AU  - Yoshihiko Kanno
AU  - Sverre E Kjeldsen
AU  - John Kostis
AU  - Kizuku Kuramoto
AU  - Jan Lanke
AU  - Edmund Lewis
AU  - Julia B Lewis
AU  - Michel Lievre
AU  - Lars H Lindholm
AU  - Jacobus Lubsen
AU  - Stephan Lueders
AU  - Stephen MacMahon
AU  - Ettore Malacco
AU  - Giuseppe Mancia
AU  - Masunori Matsuzaki
AU  - Richard J McManus
AU  - Maria H Mehlum
AU  - Bruce Neal
AU  - Steven Nissen
AU  - Hiroshi Ogawa
AU  - Toshio Ogihara
AU  - Takayoshi Ohkubo
AU  - Christopher R Palmer
AU  - Anushka Patel
AU  - Carl J Pepine
AU  - Vlado Perkovic
AU  - Marc Allan Pfeffer
AU  - Bertram Pitt
AU  - Neil R Poulter
AU  - Hiromi Rakugi
AU  - Gianpaolo Reboldi
AU  - Christopher Reid
AU  - Giuseppe Remuzzi
AU  - Anthony Rodgers
AU  - Peter Rothwell
AU  - Piero Ruggenenti
AU  - Gholamreza Salimi-Khorshidi
AU  - Takao Saruta
AU  - Joachim Schrader
AU  - Robert Schrier
AU  - Peter Sever
AU  - Peter Sleight
AU  - Jan A Staessen
AU  - Johan Sundström
AU  - Hiromichi Suzuki
AU  - Lutgarde Thijs
AU  - Fiona Turnbull
AU  - Kenji Ueshima
AU  - Seiji Umemoto
AU  - Paolo Verdecchia
AU  - Giancarlo Viberti
AU  - Kristian Wachtell
AU  - Jiguang Wang
AU  - Paul Whelton
AU  - Lindon Wing
AU  - Yoshiki Yui
AU  - Salim Yusuf
AU  - Alberto Zanchetti
AU  - Dick de Zeeuw
AU  - Zhen-Yu Zhang
PY  - 2026
JO  - The Lancet
DO  - 10.1016/s0140-6736(26)00367-3
UR  - https://doi.org/10.1016/s0140-6736(26)00367-3
ER  -

APA

Zeng, G., Bidel, Z., Yang, Q., Canoy, D., Woodward, M., Lewis, J., Kjeldsen, S. E., Cushman, W. C., Yuan, J., Teo, K., Davis, B. R., Chalmers, J., Pepine, C. J., Rahimi, K., Nazarzadeh, M., Adler, A., Agodoa, L., Algra, A., Anderson, C., Asselbergs, F. W., Baigent, C., Beckett, N. S., Berge, E., Black, H., Boersma, E., Brenner, B. M., Brouwers, F. P. J., Brown, M., Brugts, J. J., Bulpitt, C. J., Byington, R. P., Chalmers, J., Collins, R., Cutler, J., Davis, B. R., Devereaux, R. B., Dwyer, J. P., Estacio, R., Fagard, R., Fox, K., Fukui, T., Gilst, W. H. V., Gupta, A. K., Holman, R. R., Imai, Y., Ishii, M., Julius, S., Kanno, Y., Kjeldsen, S. E., Kostis, J., Kuramoto, K., Lanke, J., Lewis, E., Lewis, J. B., Lievre, M., Lindholm, L. H., Lubsen, J., Lueders, S., MacMahon, S., Malacco, E., Mancia, G., Matsuzaki, M., McManus, R. J., Mehlum, M. H., Neal, B., Nissen, S., Ogawa, H., Ogihara, T., Ohkubo, T., Palmer, C. R., Patel, A., Pepine, C. J., Perkovic, V., Pfeffer, M. A., Pitt, B., Poulter, N. R., Rakugi, H., Reboldi, G., Reid, C., Remuzzi, G., Rodgers, A., Rothwell, P., Ruggenenti, P., Salimi-Khorshidi, G., Saruta, T., Schrader, J., Schrier, R., Sever, P., Sleight, P., Staessen, J. A., Sundström, J., Suzuki, H., Thijs, L., Turnbull, F., Ueshima, K., Umemoto, S., Verdecchia, P., Viberti, G., Wachtell, K., Wang, J., Whelton, P., Wing, L., Yui, Y., Yusuf, S., Zanchetti, A., Zeeuw, D. D., & Zhang, Z. (2026). Pharmacological blood-pressure lowering for the prevention of cardiovascular disease and death across the full spectrum of chronic kidney disease severity: an individual-participant data meta-analysis. The Lancet. https://doi.org/10.1016/s0140-6736(26)00367-3

Source records

crossref · retrieved 2026-09-26T23:13:46.164Z