Cangrelor versus crushed ticagrelor in acute myocardial infarction complicated by cardiogenic shock (DAPT-SHOCK-AMI): a randomised, double-blind trial

Zuzana Motovska, Ota Hlinomaz, Jan Mrozek, Ibrahim Akin, Petr Kala, Gilles Montalescot, Milan Hromadka, Tobias Geisler, Jan Precek, Jiri Kettner, Pavel Cervinka, Stanislav Katina, Jan Pudil, Christoph B Olivier, Josef Bis, Jan Matejka, Stanislaw Bartus, Jiri Jarkovsky, Alexandra Vodzinska, Pavol Tomasov, Ahmad Zohoor, Andrea Andrasova, Ales Kovarik, Janusz Kochman, Lenka Souckova, Petr Tousek, Ivan Vulev, Jacek Kubica, Petr Ostadal, Gregory Ducrocq, Zdenek Coufal, Richard Rokyta, Iuri Marinov, Regina Demlova, Michal Karpisek, Zdenek Klimsa, Martin Hudec, Petr Widimsky, Deepak L Bhatt, Martin Kozel, Tamilla Muzafarova, Michal Mihalovic, Veronika Dantlingerova, Pavel Osmancik, Jakub Sulzenko, David Bauer, Dalibor Herman, Petr Stros, Josef Kroupa, Denisa Odvodyova, Katerina Pilikova, Frantisek Bednar, Andreas Kruger, Dagmar Vondrakova, Marek Janotka, Jan Naar, Jitka Myskova, Martin Kleissner, Marek Sramko, Martin Holek, Michal Pazdernik, Aleš Benak, Predrag Stojadinovic, Martin Blaha, Vladimir Karmazin, Marek Hrncarek, Michael Zelizko, Vladimir Porizka, Bronislav Janek, Anna Kuprova, Jana Frantova, Alena Tajovska, Jan Belohlavek, Jana Smalcova, Petr Kuchynka, Stanislav Simek, Marketa Hubatova, Martin Novak, Michal Rezek, Jan Sitar, Jiri Semenka, Ladislav Groch, Petra Kramarikova, Marketa Beranova, Rober Cyprian, Tomas Ondrus, Otakar Bocek, Petr Jerabek, Jan Kanovsky, Jiri Parenica, Martin Poloczek, Roman Stipal, Hana Jakubickova, Jirina Jecminkova, Katarina Marcinechova, Jaroslav Dusek, Miroslav Brtko, Petr Zdrahal, Jana Cervena, Abdulwasya Al Mawiri, Pavel Polansky, Josef Stasek, Jiri Karasek, Jiri Seiner, Matej Strycek, Lenka Kristofova, Martin Hutyra, Miroslav Spacek, Dagmar Hetclova, Jan Baxa, Jan Lhotsky, Ondrej Sirotek, Jitka Stocesova, Jan Mrozek, Ales Kosan, Martin Porzer, Leos Pleva, Pavel Kukla, Tomas Grezl, Josef Lastuvka, Eva Zvolankova, Vladimír Hrabos, Maryna Salomanina, Dominik Flak, Alexander Schee, Ahmad Zohoor, Petr Syrovatka, Jana Bernatova, Martin Griva, Jan Malek, Martin Rachela, Veronika Kuncova, Zdeněk Klimsa, Petr Simek, Ivan Hornacek, Miroslava Rybnickova, Radka Vondrakova, František Tousek, Tomas Sattran, David Foral, Karolina Lavickova, Libor Sknouril, Libor Gajdusek, Alexandra Vodzinska, Jakub Balusik, Jan Indrak, Jaroslav Januska, Jindrich Cerny, Jiri Fismol, Miroslav Hudec, Roman Miklik, Sarka Konderlova, Karla Netopilova, Pavlina Kufova, Tobias Geisler, Michal Droppa, Dominik Rath, Timea Keller, Isabella Kast, Monika Wensing, Christoph B. Olivier, Diona Gjermeni, Mariya Maslarska, Ibrahim Akin, Lucas Bacmeister, Adrian Heidenreich, Carina Juelch, Joana Meisenzahl, Aydin Huseynov, Michael Behnes, Gökhan Yücel, Mohammad Abumayyaleh, Stefan Bauman, Heike Dietz, Stefanie Dorn, Chantal Chevalard, Brigitte Kircher, Mathieu Kerneis, Olivier Barthelemy, Stephane Manzo-Silberman, Johanne Silvain, Arnaud Ferrante, Jean-Philippe Collet, Niki Procopi, Paul Guedeney, Tomy Salloum, Michel Zeitouni, Delphine Brugier, Karine Brochard, Guillaume Roger, Sandra Zendjebil, Helene Abergel, Axelle Fuentes, Artur Dziewierz, Tomasz Rakowski, Roman Wojdyla, Agnieszka Lenik, Alexandra Gasecka van der Pol, Ewelina Błażejowska, Agnieszka Kacperska, Piotr Niezgoda, Michal Kasprzak, Adam Sukiennik, Tomasz Bialoszynski, Lukasz Bednarczyk, Zbigniew Serafin, Przemyslaw Ratajczak, Ewa Laskowska, Elżbieta Zawada, Peter Obona, Jana Hoffmanova, Marek Strachan, Andrej Kupec, Jana Snopkova, David Liska, Peter Michalek, Denisa Brozmanova, Marian Kostelny, Marian Piestansky, Ludovit Baldovsky, Katarina Plevova

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DOI
10.1016/s0140-6736(26)00976-1
Published
2026-11
Container
The Lancet
Publisher
Elsevier BV
Open access
unknown

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@article{allodium:10.1016/s0140-6736-26-00976-1,
  title = {Cangrelor versus crushed ticagrelor in acute myocardial infarction complicated by cardiogenic shock (DAPT-SHOCK-AMI): a randomised, double-blind trial},
  author = {Zuzana Motovska and Ota Hlinomaz and Jan Mrozek and Ibrahim Akin and Petr Kala and Gilles Montalescot and Milan Hromadka and Tobias Geisler and Jan Precek and Jiri Kettner and Pavel Cervinka and Stanislav Katina and Jan Pudil and Christoph B Olivier and Josef Bis and Jan Matejka and Stanislaw Bartus and Jiri Jarkovsky and Alexandra Vodzinska and Pavol Tomasov and Ahmad Zohoor and Andrea Andrasova and Ales Kovarik and Janusz Kochman and Lenka Souckova and Petr Tousek and Ivan Vulev and Jacek Kubica and Petr Ostadal and Gregory Ducrocq and Zdenek Coufal and Richard Rokyta and Iuri Marinov and Regina Demlova and Michal Karpisek and Zdenek Klimsa and Martin Hudec and Petr Widimsky and Deepak L Bhatt and Martin Kozel and Tamilla Muzafarova and Michal Mihalovic and Veronika Dantlingerova and Pavel Osmancik and Jakub Sulzenko and David Bauer and Dalibor Herman and Petr Stros and Josef Kroupa and Denisa Odvodyova and Katerina Pilikova and Frantisek Bednar and Andreas Kruger and Dagmar Vondrakova and Marek Janotka and Jan Naar and Jitka Myskova and Martin Kleissner and Marek Sramko and Martin Holek and Michal Pazdernik and Aleš Benak and Predrag Stojadinovic and Martin Blaha and Vladimir Karmazin and Marek Hrncarek and Michael Zelizko and Vladimir Porizka and Bronislav Janek and Anna Kuprova and Jana Frantova and Alena Tajovska and Jan Belohlavek and Jana Smalcova and Petr Kuchynka and Stanislav Simek and Marketa Hubatova and Martin Novak and Michal Rezek and Jan Sitar and Jiri Semenka and Ladislav Groch and Petra Kramarikova and Marketa Beranova and Rober Cyprian and Tomas Ondrus and Otakar Bocek and Petr Jerabek and Jan Kanovsky and Jiri Parenica and Martin Poloczek and Roman Stipal and Hana Jakubickova and Jirina Jecminkova and Katarina Marcinechova and Jaroslav Dusek and Miroslav Brtko and Petr Zdrahal and Jana Cervena and Abdulwasya Al Mawiri and Pavel Polansky and Josef Stasek and Jiri Karasek and Jiri Seiner and Matej Strycek and Lenka Kristofova and Martin Hutyra and Miroslav Spacek and Dagmar Hetclova and Jan Baxa and Jan Lhotsky and Ondrej Sirotek and Jitka Stocesova and Jan Mrozek and Ales Kosan and Martin Porzer and Leos Pleva and Pavel Kukla and Tomas Grezl and Josef Lastuvka and Eva Zvolankova and Vladimír Hrabos and Maryna Salomanina and Dominik Flak and Alexander Schee and Ahmad Zohoor and Petr Syrovatka and Jana Bernatova and Martin Griva and Jan Malek and Martin Rachela and Veronika Kuncova and Zdeněk Klimsa and Petr Simek and Ivan Hornacek and Miroslava Rybnickova and Radka Vondrakova and František Tousek and Tomas Sattran and David Foral and Karolina Lavickova and Libor Sknouril and Libor Gajdusek and Alexandra Vodzinska and Jakub Balusik and Jan Indrak and Jaroslav Januska and Jindrich Cerny and Jiri Fismol and Miroslav Hudec and Roman Miklik and Sarka Konderlova and Karla Netopilova and Pavlina Kufova and Tobias Geisler and Michal Droppa and Dominik Rath and Timea Keller and Isabella Kast and Monika Wensing and Christoph B. Olivier and Diona Gjermeni and Mariya Maslarska and Ibrahim Akin and Lucas Bacmeister and Adrian Heidenreich and Carina Juelch and Joana Meisenzahl and Aydin Huseynov and Michael Behnes and Gökhan Yücel and Mohammad Abumayyaleh and Stefan Bauman and Heike Dietz and Stefanie Dorn and Chantal Chevalard and Brigitte Kircher and Mathieu Kerneis and Olivier Barthelemy and Stephane Manzo-Silberman and Johanne Silvain and Arnaud Ferrante and Jean-Philippe Collet and Niki Procopi and Paul Guedeney and Tomy Salloum and Michel Zeitouni and Delphine Brugier and Karine Brochard and Guillaume Roger and Sandra Zendjebil and Helene Abergel and Axelle Fuentes and Artur Dziewierz and Tomasz Rakowski and Roman Wojdyla and Agnieszka Lenik and Alexandra Gasecka van der Pol and Ewelina Błażejowska and Agnieszka Kacperska and Piotr Niezgoda and Michal Kasprzak and Adam Sukiennik and Tomasz Bialoszynski and Lukasz Bednarczyk and Zbigniew Serafin and Przemyslaw Ratajczak and Ewa Laskowska and Elżbieta Zawada and Peter Obona and Jana Hoffmanova and Marek Strachan and Andrej Kupec and Jana Snopkova and David Liska and Peter Michalek and Denisa Brozmanova and Marian Kostelny and Marian Piestansky and Ludovit Baldovsky and Katarina Plevova},
  year = {2026},
  journal = {The Lancet},
  doi = {10.1016/s0140-6736(26)00976-1},
  url = {https://doi.org/10.1016/s0140-6736(26)00976-1}
}

RIS

TY  - JOUR
TI  - Cangrelor versus crushed ticagrelor in acute myocardial infarction complicated by cardiogenic shock (DAPT-SHOCK-AMI): a randomised, double-blind trial
AU  - Zuzana Motovska
AU  - Ota Hlinomaz
AU  - Jan Mrozek
AU  - Ibrahim Akin
AU  - Petr Kala
AU  - Gilles Montalescot
AU  - Milan Hromadka
AU  - Tobias Geisler
AU  - Jan Precek
AU  - Jiri Kettner
AU  - Pavel Cervinka
AU  - Stanislav Katina
AU  - Jan Pudil
AU  - Christoph B Olivier
AU  - Josef Bis
AU  - Jan Matejka
AU  - Stanislaw Bartus
AU  - Jiri Jarkovsky
AU  - Alexandra Vodzinska
AU  - Pavol Tomasov
AU  - Ahmad Zohoor
AU  - Andrea Andrasova
AU  - Ales Kovarik
AU  - Janusz Kochman
AU  - Lenka Souckova
AU  - Petr Tousek
AU  - Ivan Vulev
AU  - Jacek Kubica
AU  - Petr Ostadal
AU  - Gregory Ducrocq
AU  - Zdenek Coufal
AU  - Richard Rokyta
AU  - Iuri Marinov
AU  - Regina Demlova
AU  - Michal Karpisek
AU  - Zdenek Klimsa
AU  - Martin Hudec
AU  - Petr Widimsky
AU  - Deepak L Bhatt
AU  - Martin Kozel
AU  - Tamilla Muzafarova
AU  - Michal Mihalovic
AU  - Veronika Dantlingerova
AU  - Pavel Osmancik
AU  - Jakub Sulzenko
AU  - David Bauer
AU  - Dalibor Herman
AU  - Petr Stros
AU  - Josef Kroupa
AU  - Denisa Odvodyova
AU  - Katerina Pilikova
AU  - Frantisek Bednar
AU  - Andreas Kruger
AU  - Dagmar Vondrakova
AU  - Marek Janotka
AU  - Jan Naar
AU  - Jitka Myskova
AU  - Martin Kleissner
AU  - Marek Sramko
AU  - Martin Holek
AU  - Michal Pazdernik
AU  - Aleš Benak
AU  - Predrag Stojadinovic
AU  - Martin Blaha
AU  - Vladimir Karmazin
AU  - Marek Hrncarek
AU  - Michael Zelizko
AU  - Vladimir Porizka
AU  - Bronislav Janek
AU  - Anna Kuprova
AU  - Jana Frantova
AU  - Alena Tajovska
AU  - Jan Belohlavek
AU  - Jana Smalcova
AU  - Petr Kuchynka
AU  - Stanislav Simek
AU  - Marketa Hubatova
AU  - Martin Novak
AU  - Michal Rezek
AU  - Jan Sitar
AU  - Jiri Semenka
AU  - Ladislav Groch
AU  - Petra Kramarikova
AU  - Marketa Beranova
AU  - Rober Cyprian
AU  - Tomas Ondrus
AU  - Otakar Bocek
AU  - Petr Jerabek
AU  - Jan Kanovsky
AU  - Jiri Parenica
AU  - Martin Poloczek
AU  - Roman Stipal
AU  - Hana Jakubickova
AU  - Jirina Jecminkova
AU  - Katarina Marcinechova
AU  - Jaroslav Dusek
AU  - Miroslav Brtko
AU  - Petr Zdrahal
AU  - Jana Cervena
AU  - Abdulwasya Al Mawiri
AU  - Pavel Polansky
AU  - Josef Stasek
AU  - Jiri Karasek
AU  - Jiri Seiner
AU  - Matej Strycek
AU  - Lenka Kristofova
AU  - Martin Hutyra
AU  - Miroslav Spacek
AU  - Dagmar Hetclova
AU  - Jan Baxa
AU  - Jan Lhotsky
AU  - Ondrej Sirotek
AU  - Jitka Stocesova
AU  - Jan Mrozek
AU  - Ales Kosan
AU  - Martin Porzer
AU  - Leos Pleva
AU  - Pavel Kukla
AU  - Tomas Grezl
AU  - Josef Lastuvka
AU  - Eva Zvolankova
AU  - Vladimír Hrabos
AU  - Maryna Salomanina
AU  - Dominik Flak
AU  - Alexander Schee
AU  - Ahmad Zohoor
AU  - Petr Syrovatka
AU  - Jana Bernatova
AU  - Martin Griva
AU  - Jan Malek
AU  - Martin Rachela
AU  - Veronika Kuncova
AU  - Zdeněk Klimsa
AU  - Petr Simek
AU  - Ivan Hornacek
AU  - Miroslava Rybnickova
AU  - Radka Vondrakova
AU  - František Tousek
AU  - Tomas Sattran
AU  - David Foral
AU  - Karolina Lavickova
AU  - Libor Sknouril
AU  - Libor Gajdusek
AU  - Alexandra Vodzinska
AU  - Jakub Balusik
AU  - Jan Indrak
AU  - Jaroslav Januska
AU  - Jindrich Cerny
AU  - Jiri Fismol
AU  - Miroslav Hudec
AU  - Roman Miklik
AU  - Sarka Konderlova
AU  - Karla Netopilova
AU  - Pavlina Kufova
AU  - Tobias Geisler
AU  - Michal Droppa
AU  - Dominik Rath
AU  - Timea Keller
AU  - Isabella Kast
AU  - Monika Wensing
AU  - Christoph B. Olivier
AU  - Diona Gjermeni
AU  - Mariya Maslarska
AU  - Ibrahim Akin
AU  - Lucas Bacmeister
AU  - Adrian Heidenreich
AU  - Carina Juelch
AU  - Joana Meisenzahl
AU  - Aydin Huseynov
AU  - Michael Behnes
AU  - Gökhan Yücel
AU  - Mohammad Abumayyaleh
AU  - Stefan Bauman
AU  - Heike Dietz
AU  - Stefanie Dorn
AU  - Chantal Chevalard
AU  - Brigitte Kircher
AU  - Mathieu Kerneis
AU  - Olivier Barthelemy
AU  - Stephane Manzo-Silberman
AU  - Johanne Silvain
AU  - Arnaud Ferrante
AU  - Jean-Philippe Collet
AU  - Niki Procopi
AU  - Paul Guedeney
AU  - Tomy Salloum
AU  - Michel Zeitouni
AU  - Delphine Brugier
AU  - Karine Brochard
AU  - Guillaume Roger
AU  - Sandra Zendjebil
AU  - Helene Abergel
AU  - Axelle Fuentes
AU  - Artur Dziewierz
AU  - Tomasz Rakowski
AU  - Roman Wojdyla
AU  - Agnieszka Lenik
AU  - Alexandra Gasecka van der Pol
AU  - Ewelina Błażejowska
AU  - Agnieszka Kacperska
AU  - Piotr Niezgoda
AU  - Michal Kasprzak
AU  - Adam Sukiennik
AU  - Tomasz Bialoszynski
AU  - Lukasz Bednarczyk
AU  - Zbigniew Serafin
AU  - Przemyslaw Ratajczak
AU  - Ewa Laskowska
AU  - Elżbieta Zawada
AU  - Peter Obona
AU  - Jana Hoffmanova
AU  - Marek Strachan
AU  - Andrej Kupec
AU  - Jana Snopkova
AU  - David Liska
AU  - Peter Michalek
AU  - Denisa Brozmanova
AU  - Marian Kostelny
AU  - Marian Piestansky
AU  - Ludovit Baldovsky
AU  - Katarina Plevova
PY  - 2026
JO  - The Lancet
DO  - 10.1016/s0140-6736(26)00976-1
UR  - https://doi.org/10.1016/s0140-6736(26)00976-1
ER  -

APA

Motovska, Z., Hlinomaz, O., Mrozek, J., Akin, I., Kala, P., Montalescot, G., Hromadka, M., Geisler, T., Precek, J., Kettner, J., Cervinka, P., Katina, S., Pudil, J., Olivier, C. B., Bis, J., Matejka, J., Bartus, S., Jarkovsky, J., Vodzinska, A., Tomasov, P., Zohoor, A., Andrasova, A., Kovarik, A., Kochman, J., Souckova, L., Tousek, P., Vulev, I., Kubica, J., Ostadal, P., Ducrocq, G., Coufal, Z., Rokyta, R., Marinov, I., Demlova, R., Karpisek, M., Klimsa, Z., Hudec, M., Widimsky, P., Bhatt, D. L., Kozel, M., Muzafarova, T., Mihalovic, M., Dantlingerova, V., Osmancik, P., Sulzenko, J., Bauer, D., Herman, D., Stros, P., Kroupa, J., Odvodyova, D., Pilikova, K., Bednar, F., Kruger, A., Vondrakova, D., Janotka, M., Naar, J., Myskova, J., Kleissner, M., Sramko, M., Holek, M., Pazdernik, M., Benak, A., Stojadinovic, P., Blaha, M., Karmazin, V., Hrncarek, M., Zelizko, M., Porizka, V., Janek, B., Kuprova, A., Frantova, J., Tajovska, A., Belohlavek, J., Smalcova, J., Kuchynka, P., Simek, S., Hubatova, M., Novak, M., Rezek, M., Sitar, J., Semenka, J., Groch, L., Kramarikova, P., Beranova, M., Cyprian, R., Ondrus, T., Bocek, O., Jerabek, P., Kanovsky, J., Parenica, J., Poloczek, M., Stipal, R., Jakubickova, H., Jecminkova, J., Marcinechova, K., Dusek, J., Brtko, M., Zdrahal, P., Cervena, J., Mawiri, A. A., Polansky, P., Stasek, J., Karasek, J., Seiner, J., Strycek, M., Kristofova, L., Hutyra, M., Spacek, M., Hetclova, D., Baxa, J., Lhotsky, J., Sirotek, O., Stocesova, J., Mrozek, J., Kosan, A., Porzer, M., Pleva, L., Kukla, P., Grezl, T., Lastuvka, J., Zvolankova, E., Hrabos, V., Salomanina, M., Flak, D., Schee, A., Zohoor, A., Syrovatka, P., Bernatova, J., Griva, M., Malek, J., Rachela, M., Kuncova, V., Klimsa, Z., Simek, P., Hornacek, I., Rybnickova, M., Vondrakova, R., Tousek, F., Sattran, T., Foral, D., Lavickova, K., Sknouril, L., Gajdusek, L., Vodzinska, A., Balusik, J., Indrak, J., Januska, J., Cerny, J., Fismol, J., Hudec, M., Miklik, R., Konderlova, S., Netopilova, K., Kufova, P., Geisler, T., Droppa, M., Rath, D., Keller, T., Kast, I., Wensing, M., Olivier, C. B., Gjermeni, D., Maslarska, M., Akin, I., Bacmeister, L., Heidenreich, A., Juelch, C., Meisenzahl, J., Huseynov, A., Behnes, M., Yücel, G., Abumayyaleh, M., Bauman, S., Dietz, H., Dorn, S., Chevalard, C., Kircher, B., Kerneis, M., Barthelemy, O., Manzo-Silberman, S., Silvain, J., Ferrante, A., Collet, J., Procopi, N., Guedeney, P., Salloum, T., Zeitouni, M., Brugier, D., Brochard, K., Roger, G., Zendjebil, S., Abergel, H., Fuentes, A., Dziewierz, A., Rakowski, T., Wojdyla, R., Lenik, A., Pol, A. G. V. D., Błażejowska, E., Kacperska, A., Niezgoda, P., Kasprzak, M., Sukiennik, A., Bialoszynski, T., Bednarczyk, L., Serafin, Z., Ratajczak, P., Laskowska, E., Zawada, E., Obona, P., Hoffmanova, J., Strachan, M., Kupec, A., Snopkova, J., Liska, D., Michalek, P., Brozmanova, D., Kostelny, M., Piestansky, M., Baldovsky, L., & Plevova, K. (2026). Cangrelor versus crushed ticagrelor in acute myocardial infarction complicated by cardiogenic shock (DAPT-SHOCK-AMI): a randomised, double-blind trial. The Lancet. https://doi.org/10.1016/s0140-6736(26)00976-1

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