Switch to once-weekly, single-tablet islatravir-lenacapavir from daily standard of care for HIV-1 (ISLEND-2): a multicentre, randomised, open-label, active-controlled, phase 3 non-inferiority trial.

Colson AE, Kumar PN, Ruane PJ, Chetchotisakd P, Ratanasuwan W, Liberty A, Nahass RG, Arenas-Pinto A, Post FA, Baker DA, Cahn P, Hofmann E, Watanabe D, Lu PL, Roukens AHE, Parczewski M, Wang H, Chen K, Shihadeh F, Shaughnessy M, Dvory-Sobol H, SenGupta D, Llamoso C, Rhee M, Ogbuagu O, ISLEND-2 Study Team

Open source

DOI
10.1016/s0140-6736(26)01442-x
Published
2026 Aug 29
Container
Lancet (London, England)
Publisher
Not recorded
Open access
unknown

Credibility signals

limited evidence Score 43/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

Cite this work

BibTeX

@article{allodium:10.1016/s0140-6736-26-01442-x,
  title = {Switch to once-weekly, single-tablet islatravir-lenacapavir from daily standard of care for HIV-1 (ISLEND-2): a multicentre, randomised, open-label, active-controlled, phase 3 non-inferiority trial.},
  author = {Colson AE and Kumar PN and Ruane PJ and Chetchotisakd P and Ratanasuwan W and Liberty A and Nahass RG and Arenas-Pinto A and Post FA and Baker DA and Cahn P and Hofmann E and Watanabe D and Lu PL and Roukens AHE and Parczewski M and Wang H and Chen K and Shihadeh F and Shaughnessy M and Dvory-Sobol H and SenGupta D and Llamoso C and Rhee M and Ogbuagu O and ISLEND-2 Study Team},
  year = {2026},
  journal = {Lancet (London, England)},
  doi = {10.1016/s0140-6736(26)01442-x},
  url = {https://doi.org/10.1016/s0140-6736(26)01442-x}
}

RIS

TY  - JOUR
TI  - Switch to once-weekly, single-tablet islatravir-lenacapavir from daily standard of care for HIV-1 (ISLEND-2): a multicentre, randomised, open-label, active-controlled, phase 3 non-inferiority trial.
AU  - Colson AE
AU  - Kumar PN
AU  - Ruane PJ
AU  - Chetchotisakd P
AU  - Ratanasuwan W
AU  - Liberty A
AU  - Nahass RG
AU  - Arenas-Pinto A
AU  - Post FA
AU  - Baker DA
AU  - Cahn P
AU  - Hofmann E
AU  - Watanabe D
AU  - Lu PL
AU  - Roukens AHE
AU  - Parczewski M
AU  - Wang H
AU  - Chen K
AU  - Shihadeh F
AU  - Shaughnessy M
AU  - Dvory-Sobol H
AU  - SenGupta D
AU  - Llamoso C
AU  - Rhee M
AU  - Ogbuagu O
AU  - ISLEND-2 Study Team
PY  - 2026
JO  - Lancet (London, England)
DO  - 10.1016/s0140-6736(26)01442-x
UR  - https://doi.org/10.1016/s0140-6736(26)01442-x
ER  - 

APA

AE, C., PN, K., PJ, R., P, C., W, R., A, L., RG, N., A, A., FA, P., DA, B., P, C., E, H., D, W., PL, L., AHE, R., M, P., H, W., K, C., F, S., M, S., H, D., D, S., C, L., M, R., O, O., & Team, I. S. (2026). Switch to once-weekly, single-tablet islatravir-lenacapavir from daily standard of care for HIV-1 (ISLEND-2): a multicentre, randomised, open-label, active-controlled, phase 3 non-inferiority trial.. Lancet (London, England). https://doi.org/10.1016/s0140-6736(26)01442-x

Source records