Prone positioning and high-frequency oscillatory ventilation in early paediatric acute respiratory distress syndrome (PROSpect): an international, two-by-two factorial, response-adaptive, phase 3, randomised controlled trial

Martha A Q Curley, Martin C J Kneyber, Ira M Cheifetz, Michele Kong, Sidharth Mahapatra, Adam J Schwarz, Suwannee Phumeetham, Katherine Irby, Natalie Napolitano, Onella S Dawkins-Henry, Emily E Birch, Corrine F Elliott, Lindsay R Berry, Kevin J Downes, Aruna Natarajan, Michelle A Detry, Kert Viele, Todd L Graves, Michael Matthay, Lisa A Asaro, David Wypij, Michele Kong, Sidharth Mahapatra, Martin C.J. Kneyber, Adam J. Schwarz, Suwannee Phumeetham, Musaab Ramsi, Rujipat Samransamruajkit, Nattachai Anantasit, Andrew K. Feng, Regina Grigolli Cesar, José Colleti Junior, Courtney M. Rowan, Katherine Irby, Anupama Yerra, Sapna R. Kudchadkar, Heidi R. Flori, Emilie Henry, Kari Wellnitz, James B. Schneider, Simon J. Erickson, Guillaume Emeriaud, Jasmine C. Dowell, Diane Peng, Himanshu Aneja, Elizabeth E. Zivick, Lauren R. Sorce, Bria Coates, Peter M. Luckett, Neal J. Thomas, Chin Seng Gan, Soo Lin Chuah, Cristina Giugni, Palen Mallory, Reinout J. Mildner, Matteo Di Nardo, Camilla Micalizzi, Ezra Weinblatt, Charles Bergstrom, Melissa B. Porter, Matei Petrescu, Niveditha Balakumar, Timothy T. Cornell, Katja Masjosthusmann, Neelima Marupudi, Jorge Selandari, G. Kris Bysani, Shweta Murthi, Jeremy Tong, Rana Sharara-Chami

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DOI: 10.1016/s0140-6736(26)01949-5
Published: 2026-10
Container: The Lancet
Publisher: Elsevier BV
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1016/s0140-6736-26-01949-5,
title = {Prone positioning and high-frequency oscillatory ventilation in early paediatric acute respiratory distress syndrome (PROSpect): an international, two-by-two factorial, response-adaptive, phase 3, randomised controlled trial},
author = {Martha A Q Curley and Martin C J Kneyber and Ira M Cheifetz and Michele Kong and Sidharth Mahapatra and Adam J Schwarz and Suwannee Phumeetham and Katherine Irby and Natalie Napolitano and Onella S Dawkins-Henry and Emily E Birch and Corrine F Elliott and Lindsay R Berry and Kevin J Downes and Aruna Natarajan and Michelle A Detry and Kert Viele and Todd L Graves and Michael Matthay and Lisa A Asaro and David Wypij and Michele Kong and Sidharth Mahapatra and Martin C.J. Kneyber and Adam J. Schwarz and Suwannee Phumeetham and Musaab Ramsi and Rujipat Samransamruajkit and Nattachai Anantasit and Andrew K. Feng and Regina Grigolli Cesar and José Colleti Junior and Courtney M. Rowan and Katherine Irby and Anupama Yerra and Sapna R. Kudchadkar and Heidi R. Flori and Emilie Henry and Kari Wellnitz and James B. Schneider and Simon J. Erickson and Guillaume Emeriaud and Jasmine C. Dowell and Diane Peng and Himanshu Aneja and Elizabeth E. Zivick and Lauren R. Sorce and Bria Coates and Peter M. Luckett and Neal J. Thomas and Chin Seng Gan and Soo Lin Chuah and Cristina Giugni and Palen Mallory and Reinout J. Mildner and Matteo Di Nardo and Camilla Micalizzi and Ezra Weinblatt and Charles Bergstrom and Melissa B. Porter and Matei Petrescu and Niveditha Balakumar and Timothy T. Cornell and Katja Masjosthusmann and Neelima Marupudi and Jorge Selandari and G. Kris Bysani and Shweta Murthi and Jeremy Tong and Rana Sharara-Chami},
year = {2026},
journal = {The Lancet},
doi = {10.1016/s0140-6736(26)01949-5},
url = {https://doi.org/10.1016/s0140-6736(26)01949-5}
}

RIS

TY  - JOUR
TI  - Prone positioning and high-frequency oscillatory ventilation in early paediatric acute respiratory distress syndrome (PROSpect): an international, two-by-two factorial, response-adaptive, phase 3, randomised controlled trial
AU  - Martha A Q Curley
AU  - Martin C J Kneyber
AU  - Ira M Cheifetz
AU  - Michele Kong
AU  - Sidharth Mahapatra
AU  - Adam J Schwarz
AU  - Suwannee Phumeetham
AU  - Katherine Irby
AU  - Natalie Napolitano
AU  - Onella S Dawkins-Henry
AU  - Emily E Birch
AU  - Corrine F Elliott
AU  - Lindsay R Berry
AU  - Kevin J Downes
AU  - Aruna Natarajan
AU  - Michelle A Detry
AU  - Kert Viele
AU  - Todd L Graves
AU  - Michael Matthay
AU  - Lisa A Asaro
AU  - David Wypij
AU  - Michele Kong
AU  - Sidharth Mahapatra
AU  - Martin C.J. Kneyber
AU  - Adam J. Schwarz
AU  - Suwannee Phumeetham
AU  - Musaab Ramsi
AU  - Rujipat Samransamruajkit
AU  - Nattachai Anantasit
AU  - Andrew K. Feng
AU  - Regina Grigolli Cesar
AU  - José Colleti Junior
AU  - Courtney M. Rowan
AU  - Katherine Irby
AU  - Anupama Yerra
AU  - Sapna R. Kudchadkar
AU  - Heidi R. Flori
AU  - Emilie Henry
AU  - Kari Wellnitz
AU  - James B. Schneider
AU  - Simon J. Erickson
AU  - Guillaume Emeriaud
AU  - Jasmine C. Dowell
AU  - Diane Peng
AU  - Himanshu Aneja
AU  - Elizabeth E. Zivick
AU  - Lauren R. Sorce
AU  - Bria Coates
AU  - Peter M. Luckett
AU  - Neal J. Thomas
AU  - Chin Seng Gan
AU  - Soo Lin Chuah
AU  - Cristina Giugni
AU  - Palen Mallory
AU  - Reinout J. Mildner
AU  - Matteo Di Nardo
AU  - Camilla Micalizzi
AU  - Ezra Weinblatt
AU  - Charles Bergstrom
AU  - Melissa B. Porter
AU  - Matei Petrescu
AU  - Niveditha Balakumar
AU  - Timothy T. Cornell
AU  - Katja Masjosthusmann
AU  - Neelima Marupudi
AU  - Jorge Selandari
AU  - G. Kris Bysani
AU  - Shweta Murthi
AU  - Jeremy Tong
AU  - Rana Sharara-Chami
PY  - 2026
JO  - The Lancet
DO  - 10.1016/s0140-6736(26)01949-5
UR  - https://doi.org/10.1016/s0140-6736(26)01949-5
ER  -

APA

Curley, M. A. Q., Kneyber, M. C. J., Cheifetz, I. M., Kong, M., Mahapatra, S., Schwarz, A. J., Phumeetham, S., Irby, K., Napolitano, N., Dawkins-Henry, O. S., Birch, E. E., Elliott, C. F., Berry, L. R., Downes, K. J., Natarajan, A., Detry, M. A., Viele, K., Graves, T. L., Matthay, M., Asaro, L. A., Wypij, D., Kong, M., Mahapatra, S., Kneyber, M. C., Schwarz, A. J., Phumeetham, S., Ramsi, M., Samransamruajkit, R., Anantasit, N., Feng, A. K., Cesar, R. G., Junior, J. C., Rowan, C. M., Irby, K., Yerra, A., Kudchadkar, S. R., Flori, H. R., Henry, E., Wellnitz, K., Schneider, J. B., Erickson, S. J., Emeriaud, G., Dowell, J. C., Peng, D., Aneja, H., Zivick, E. E., Sorce, L. R., Coates, B., Luckett, P. M., Thomas, N. J., Gan, C. S., Chuah, S. L., Giugni, C., Mallory, P., Mildner, R. J., Nardo, M. D., Micalizzi, C., Weinblatt, E., Bergstrom, C., Porter, M. B., Petrescu, M., Balakumar, N., Cornell, T. T., Masjosthusmann, K., Marupudi, N., Selandari, J., Bysani, G. K., Murthi, S., Tong, J., & Sharara-Chami, R. (2026). Prone positioning and high-frequency oscillatory ventilation in early paediatric acute respiratory distress syndrome (PROSpect): an international, two-by-two factorial, response-adaptive, phase 3, randomised controlled trial. The Lancet. https://doi.org/10.1016/s0140-6736(26)01949-5

Source records

crossref · retrieved 2026-11-10T12:40:22.080Z