Sacituzumab tirumotecan versus treatment of physician's choice in previously treated endometrial cancer (TroFuse-005/ENGOT-en23/GOG-3095): a randomised, open-label, phase 3 trial

BibTeX

@article{allodium:10.1016/s0140-6736-26-02099-4,
  title = {Sacituzumab tirumotecan versus treatment of physician's choice in previously treated endometrial cancer (TroFuse-005/ENGOT-en23/GOG-3095): a randomised, open-label, phase 3 trial},
  author = {Domenica Lorusso and Jérôme Martin-Babau and Floor Backes and Maria Pilar Barretina Ginesta and Jacob Korach and Shibani Nicum and Julian Wampfler and Jianqing Zhu and Monika Ducceschi and Toon Van Gorp and Magnus Frödin-Bolling and Flora Zagouri and Judith R Kroep and Isabelle Ray-Coquard and Vanda Salutari and Michelle D S Lightfoot and Todd Tillmanns and David M O’Malley and Kosei Hasegawa and Jung-Yun Lee and Gonzalo H Giornelli and Vanessa Samouëlian and Yoland Antill and Jundong Li and Shin Nishio and Jack Junjie Chan and Bradley J Monk and Chenxiang Li and Kristina Woodhouse and Robert Orlowski and Carmen García-Duran and Bhavana Pothuri and Cyril Abdeddaim and Ana Fonseca Alves and Yunting An and Sumitra Ananda and Raul Andrade-Moreno and Yoland Antill and Eder Arango-Bravo and Kazuya Ariyoshi and Annika Auranen and Tsukasa Baba and Floor Backes and Pilar Barretina Ginesta and Michele Bartoletti and Maria Bell and Mariusz Bidzinski and Destin Black and Stephanie Blank and Lubomir Bodnar and Alessandra Bologna and Rachel Bramblet and Donal Brennan and Joseph Buscema and Maria Caceres and Karen Cadoo and Fernanda Casarotto and Julio Cesar Prestes and John Chan and Junjie Jack Chan and Dana Chase and Christos Christodoulou and Athina Christopoulou and David Cibula and Andrew Clamp and Dearbhaile Collins and Ilaria Colombo and Nicoletta Colombo and Pierre Combe and Sarah Crafton and Juan Cundom and Marlies De Bock and Nikolaus de Gregorio and Joseph de la Garza and Thibault de la Motte Rouge and Maximo De la Vega and Hannelore Denys and Connie Diakos and Christina Duncan-Lothamer and Ram Eitan and Mostafa El Naggar and Tobias Engler and Annamaria Ferrero and Suzanne Fortin and Gisela Franco and Magnus Frödin-Bolling and Akiko Furusawa and Carlos Gallardo and Alejandro Gallego Martinez and Bo Gao and Carmen García Durán and Sharad Ghamande and Prafull Ghatage and Marta Gil Martin and Lucy Gilbert and Gonzalo Giornelli and Laurence Gladieff and Jeffrey Goh and Gonzalo Gomez Abuin and Martina Gropp-Meier and Michael Halaska and Melissa Hardesty and Kosei Hasegawa and Ursula Hasler-Strub and Viola Heinzelmann-Schwarz and Florian Heitz and Stéphanie Henry and Rebecca Herbertson and Sakari Hietanen and Robert Higgins and Robert Holloway and Atsushi Horiike and Ebony Hoskins and Yan Hu and Yi Huang and Carolina Ibanez and Vibeke Anett Ingebrigtsen and Amanda Jackson and Mary Tilley Jenkins Vogel and Amelia Jernigan and Nate Jones and Diego Kaen and Margaux Kanis and Ashleigh Kerr and Akira Kikuchi and Jae-Weon Kim and Yong Beom Kim and Miho Kitai and Jacob Korach and Anjila Koul and Rebecca Kristeleit and Kristina Kristoffersen and Judith Kroep and Jan Kummel and Heini Lassus and Coriolan Lebreton and Christine Lee and Jeong-Won Lee and Jung-Yun Lee and Shin Wha Lee and Yi-Chun Lee and Talia Levy and Sharyn Lewin and Congzhu Li and Guiling Li and Jundong Li and Xiumin Li and Sihai Liao and Michelle Lightfoot and Peter Lim and An Lin and Kristina Lindemann and Revital Linder and Domenica Lorusso and Jose Luiz Guimaraes and Xuezhen Luo and Weiguo Lv and Beata Mackowiak-Matejczyk and Manuel Magallanes Maciel and Luis Manso Sanchez and Laura Mansi and Frederik Marmè and Christian Marth and Jerome Martin-Babau and Cicero Martins and Hanne Mathiesen and Corinne Maurice and John McGrane and Donna McNamara and Bohuslav Melichar and Renata Meneguetti and Jinwei Miao and Bradley Monk and Mariana Monteiro and Lea Moukarzel and Emanuele Naglieri and Kazuto Nakamura and Toshiaki Nakamura and Shibani Nicum and Shin Nishio and Matthew Oliver and Petronella Ottevanger and Jose Perez Fidalgo and Klaus Pietzner and Carmela Pisano and Stephan Polterauer and Stanislas Quesada and Nicoline Raaschou-Jensen and Pedro Ramirez and Francesco Raspagliesi and Isabelle-Laure Ray-Coquard and Andres Redondo Sanchez and Adriana Regina and Roberto Romero Diaz and Maria Romero Lagunes and Ignacio Romero Noguera and Ora Rosengarten and Maria Jesus Rubio Perez and Jeanelle Sabourin and Tamar Safra and Pamela Salazar and Vanda Salutari and Vanessa Samouelian and Alessandro Santin and Andrea Santin and Armando Santoro and Luis Santos-Reyes and Toyomi Satoh and Angeles Secord and Frederic Selle and Greg Sfakianos and Brian Slomovitz and Vicky Soomers and Shiro Suzuki and Ioannis Syrios and Kazuhiro Takehara and Jie Tang and Alexandra Taylor and Nana Tchabo and Meaghan Tenney and Premal Thaker and Todd Tillmanns and Vojtech Tlusty and Germana Tognon and Federica Tomao and Cecilie Torkildsen and Fabian Trillsch and Jacqueline Tromp and Marjo Tuppurainen and Luigi Carlo Turco and Bartosz Urbanski and Tomoka Usami and Toon Van Gorp and Hector Velez-Cortes and Karina Vera and Ingvild Vistad and Christof Vulsteke and Julian Wampfler and Zamaniah Wan Ishak Wan and Li Wang and Luanhong Wang and Wuliang Wang and Yaxian Wang and Yu Wang and Hidemichi Watari and Xiaowei Wei and Vit Weinberger and Lyndsay Willmott and Pauline Wimberger and Wataru Yamagami and Eduardo Yanez Ruiz and Haihua Yang and Xielan Yang and Rutie Yin and Daniel Yokom and Kan Yonemori and Jianlin Yuan and Mayu Yunokawa and Mastura Md Yusof and Flora Zagouri and Claudio Zamagni and Bingzhong Zhang and Guonan Zhang and Jieqing Zhang and Mingjun Zhang and Yu Zhang and Yunyan Zhang and Genhai Zhu and Jianqing Zhu and Michal Zikan and Susan Zweizig},
  year = {2026},
  journal = {The Lancet},
  doi = {10.1016/s0140-6736(26)02099-4},
  url = {https://doi.org/10.1016/s0140-6736(26)02099-4}
}

RIS

TY  - JOUR
TI  - Sacituzumab tirumotecan versus treatment of physician's choice in previously treated endometrial cancer (TroFuse-005/ENGOT-en23/GOG-3095): a randomised, open-label, phase 3 trial
AU  - Domenica Lorusso
AU  - Jérôme Martin-Babau
AU  - Floor Backes
AU  - Maria Pilar Barretina Ginesta
AU  - Jacob Korach
AU  - Shibani Nicum
AU  - Julian Wampfler
AU  - Jianqing Zhu
AU  - Monika Ducceschi
AU  - Toon Van Gorp
AU  - Magnus Frödin-Bolling
AU  - Flora Zagouri
AU  - Judith R Kroep
AU  - Isabelle Ray-Coquard
AU  - Vanda Salutari
AU  - Michelle D S Lightfoot
AU  - Todd Tillmanns
AU  - David M O’Malley
AU  - Kosei Hasegawa
AU  - Jung-Yun Lee
AU  - Gonzalo H Giornelli
AU  - Vanessa Samouëlian
AU  - Yoland Antill
AU  - Jundong Li
AU  - Shin Nishio
AU  - Jack Junjie Chan
AU  - Bradley J Monk
AU  - Chenxiang Li
AU  - Kristina Woodhouse
AU  - Robert Orlowski
AU  - Carmen García-Duran
AU  - Bhavana Pothuri
AU  - Cyril Abdeddaim
AU  - Ana Fonseca Alves
AU  - Yunting An
AU  - Sumitra Ananda
AU  - Raul Andrade-Moreno
AU  - Yoland Antill
AU  - Eder Arango-Bravo
AU  - Kazuya Ariyoshi
AU  - Annika Auranen
AU  - Tsukasa Baba
AU  - Floor Backes
AU  - Pilar Barretina Ginesta
AU  - Michele Bartoletti
AU  - Maria Bell
AU  - Mariusz Bidzinski
AU  - Destin Black
AU  - Stephanie Blank
AU  - Lubomir Bodnar
AU  - Alessandra Bologna
AU  - Rachel Bramblet
AU  - Donal Brennan
AU  - Joseph Buscema
AU  - Maria Caceres
AU  - Karen Cadoo
AU  - Fernanda Casarotto
AU  - Julio Cesar Prestes
AU  - John Chan
AU  - Junjie Jack Chan
AU  - Dana Chase
AU  - Christos Christodoulou
AU  - Athina Christopoulou
AU  - David Cibula
AU  - Andrew Clamp
AU  - Dearbhaile Collins
AU  - Ilaria Colombo
AU  - Nicoletta Colombo
AU  - Pierre Combe
AU  - Sarah Crafton
AU  - Juan Cundom
AU  - Marlies De Bock
AU  - Nikolaus de Gregorio
AU  - Joseph de la Garza
AU  - Thibault de la Motte Rouge
AU  - Maximo De la Vega
AU  - Hannelore Denys
AU  - Connie Diakos
AU  - Christina Duncan-Lothamer
AU  - Ram Eitan
AU  - Mostafa El Naggar
AU  - Tobias Engler
AU  - Annamaria Ferrero
AU  - Suzanne Fortin
AU  - Gisela Franco
AU  - Magnus Frödin-Bolling
AU  - Akiko Furusawa
AU  - Carlos Gallardo
AU  - Alejandro Gallego Martinez
AU  - Bo Gao
AU  - Carmen García Durán
AU  - Sharad Ghamande
AU  - Prafull Ghatage
AU  - Marta Gil Martin
AU  - Lucy Gilbert
AU  - Gonzalo Giornelli
AU  - Laurence Gladieff
AU  - Jeffrey Goh
AU  - Gonzalo Gomez Abuin
AU  - Martina Gropp-Meier
AU  - Michael Halaska
AU  - Melissa Hardesty
AU  - Kosei Hasegawa
AU  - Ursula Hasler-Strub
AU  - Viola Heinzelmann-Schwarz
AU  - Florian Heitz
AU  - Stéphanie Henry
AU  - Rebecca Herbertson
AU  - Sakari Hietanen
AU  - Robert Higgins
AU  - Robert Holloway
AU  - Atsushi Horiike
AU  - Ebony Hoskins
AU  - Yan Hu
AU  - Yi Huang
AU  - Carolina Ibanez
AU  - Vibeke Anett Ingebrigtsen
AU  - Amanda Jackson
AU  - Mary Tilley Jenkins Vogel
AU  - Amelia Jernigan
AU  - Nate Jones
AU  - Diego Kaen
AU  - Margaux Kanis
AU  - Ashleigh Kerr
AU  - Akira Kikuchi
AU  - Jae-Weon Kim
AU  - Yong Beom Kim
AU  - Miho Kitai
AU  - Jacob Korach
AU  - Anjila Koul
AU  - Rebecca Kristeleit
AU  - Kristina Kristoffersen
AU  - Judith Kroep
AU  - Jan Kummel
AU  - Heini Lassus
AU  - Coriolan Lebreton
AU  - Christine Lee
AU  - Jeong-Won Lee
AU  - Jung-Yun Lee
AU  - Shin Wha Lee
AU  - Yi-Chun Lee
AU  - Talia Levy
AU  - Sharyn Lewin
AU  - Congzhu Li
AU  - Guiling Li
AU  - Jundong Li
AU  - Xiumin Li
AU  - Sihai Liao
AU  - Michelle Lightfoot
AU  - Peter Lim
AU  - An Lin
AU  - Kristina Lindemann
AU  - Revital Linder
AU  - Domenica Lorusso
AU  - Jose Luiz Guimaraes
AU  - Xuezhen Luo
AU  - Weiguo Lv
AU  - Beata Mackowiak-Matejczyk
AU  - Manuel Magallanes Maciel
AU  - Luis Manso Sanchez
AU  - Laura Mansi
AU  - Frederik Marmè
AU  - Christian Marth
AU  - Jerome Martin-Babau
AU  - Cicero Martins
AU  - Hanne Mathiesen
AU  - Corinne Maurice
AU  - John McGrane
AU  - Donna McNamara
AU  - Bohuslav Melichar
AU  - Renata Meneguetti
AU  - Jinwei Miao
AU  - Bradley Monk
AU  - Mariana Monteiro
AU  - Lea Moukarzel
AU  - Emanuele Naglieri
AU  - Kazuto Nakamura
AU  - Toshiaki Nakamura
AU  - Shibani Nicum
AU  - Shin Nishio
AU  - Matthew Oliver
AU  - Petronella Ottevanger
AU  - Jose Perez Fidalgo
AU  - Klaus Pietzner
AU  - Carmela Pisano
AU  - Stephan Polterauer
AU  - Stanislas Quesada
AU  - Nicoline Raaschou-Jensen
AU  - Pedro Ramirez
AU  - Francesco Raspagliesi
AU  - Isabelle-Laure Ray-Coquard
AU  - Andres Redondo Sanchez
AU  - Adriana Regina
AU  - Roberto Romero Diaz
AU  - Maria Romero Lagunes
AU  - Ignacio Romero Noguera
AU  - Ora Rosengarten
AU  - Maria Jesus Rubio Perez
AU  - Jeanelle Sabourin
AU  - Tamar Safra
AU  - Pamela Salazar
AU  - Vanda Salutari
AU  - Vanessa Samouelian
AU  - Alessandro Santin
AU  - Andrea Santin
AU  - Armando Santoro
AU  - Luis Santos-Reyes
AU  - Toyomi Satoh
AU  - Angeles Secord
AU  - Frederic Selle
AU  - Greg Sfakianos
AU  - Brian Slomovitz
AU  - Vicky Soomers
AU  - Shiro Suzuki
AU  - Ioannis Syrios
AU  - Kazuhiro Takehara
AU  - Jie Tang
AU  - Alexandra Taylor
AU  - Nana Tchabo
AU  - Meaghan Tenney
AU  - Premal Thaker
AU  - Todd Tillmanns
AU  - Vojtech Tlusty
AU  - Germana Tognon
AU  - Federica Tomao
AU  - Cecilie Torkildsen
AU  - Fabian Trillsch
AU  - Jacqueline Tromp
AU  - Marjo Tuppurainen
AU  - Luigi Carlo Turco
AU  - Bartosz Urbanski
AU  - Tomoka Usami
AU  - Toon Van Gorp
AU  - Hector Velez-Cortes
AU  - Karina Vera
AU  - Ingvild Vistad
AU  - Christof Vulsteke
AU  - Julian Wampfler
AU  - Zamaniah Wan Ishak Wan
AU  - Li Wang
AU  - Luanhong Wang
AU  - Wuliang Wang
AU  - Yaxian Wang
AU  - Yu Wang
AU  - Hidemichi Watari
AU  - Xiaowei Wei
AU  - Vit Weinberger
AU  - Lyndsay Willmott
AU  - Pauline Wimberger
AU  - Wataru Yamagami
AU  - Eduardo Yanez Ruiz
AU  - Haihua Yang
AU  - Xielan Yang
AU  - Rutie Yin
AU  - Daniel Yokom
AU  - Kan Yonemori
AU  - Jianlin Yuan
AU  - Mayu Yunokawa
AU  - Mastura Md Yusof
AU  - Flora Zagouri
AU  - Claudio Zamagni
AU  - Bingzhong Zhang
AU  - Guonan Zhang
AU  - Jieqing Zhang
AU  - Mingjun Zhang
AU  - Yu Zhang
AU  - Yunyan Zhang
AU  - Genhai Zhu
AU  - Jianqing Zhu
AU  - Michal Zikan
AU  - Susan Zweizig
PY  - 2026
JO  - The Lancet
DO  - 10.1016/s0140-6736(26)02099-4
UR  - https://doi.org/10.1016/s0140-6736(26)02099-4
ER  - 

APA

Lorusso, D., Martin-Babau, J., Backes, F., Ginesta, M. P. B., Korach, J., Nicum, S., Wampfler, J., Zhu, J., Ducceschi, M., Gorp, T. V., Frödin-Bolling, M., Zagouri, F., Kroep, J. R., Ray-Coquard, I., Salutari, V., Lightfoot, M. D. S., Tillmanns, T., O’Malley, D. M., Hasegawa, K., Lee, J., Giornelli, G. H., Samouëlian, V., Antill, Y., Li, J., Nishio, S., Chan, J. J., Monk, B. J., Li, C., Woodhouse, K., Orlowski, R., García-Duran, C., Pothuri, B., Abdeddaim, C., Alves, A. F., An, Y., Ananda, S., Andrade-Moreno, R., Antill, Y., Arango-Bravo, E., Ariyoshi, K., Auranen, A., Baba, T., Backes, F., Ginesta, P. B., Bartoletti, M., Bell, M., Bidzinski, M., Black, D., Blank, S., Bodnar, L., Bologna, A., Bramblet, R., Brennan, D., Buscema, J., Caceres, M., Cadoo, K., Casarotto, F., Prestes, J. C., Chan, J., Chan, J. J., Chase, D., Christodoulou, C., Christopoulou, A., Cibula, D., Clamp, A., Collins, D., Colombo, I., Colombo, N., Combe, P., Crafton, S., Cundom, J., Bock, M. D., Gregorio, N. D., Garza, J. D. L., Rouge, T. D. L. M., Vega, M. D. L., Denys, H., Diakos, C., Duncan-Lothamer, C., Eitan, R., Naggar, M. E., Engler, T., Ferrero, A., Fortin, S., Franco, G., Frödin-Bolling, M., Furusawa, A., Gallardo, C., Martinez, A. G., Gao, B., Durán, C. G., Ghamande, S., Ghatage, P., Martin, M. G., Gilbert, L., Giornelli, G., Gladieff, L., Goh, J., Abuin, G. G., Gropp-Meier, M., Halaska, M., Hardesty, M., Hasegawa, K., Hasler-Strub, U., Heinzelmann-Schwarz, V., Heitz, F., Henry, S., Herbertson, R., Hietanen, S., Higgins, R., Holloway, R., Horiike, A., Hoskins, E., Hu, Y., Huang, Y., Ibanez, C., Ingebrigtsen, V. A., Jackson, A., Vogel, M. T. J., Jernigan, A., Jones, N., Kaen, D., Kanis, M., Kerr, A., Kikuchi, A., Kim, J., Kim, Y. B., Kitai, M., Korach, J., Koul, A., Kristeleit, R., Kristoffersen, K., Kroep, J., Kummel, J., Lassus, H., Lebreton, C., Lee, C., Lee, J., Lee, J., Lee, S. W., Lee, Y., Levy, T., Lewin, S., Li, C., Li, G., Li, J., Li, X., Liao, S., Lightfoot, M., Lim, P., Lin, A., Lindemann, K., Linder, R., Lorusso, D., Guimaraes, J. L., Luo, X., Lv, W., Mackowiak-Matejczyk, B., Maciel, M. M., Sanchez, L. M., Mansi, L., Marmè, F., Marth, C., Martin-Babau, J., Martins, C., Mathiesen, H., Maurice, C., McGrane, J., McNamara, D., Melichar, B., Meneguetti, R., Miao, J., Monk, B., Monteiro, M., Moukarzel, L., Naglieri, E., Nakamura, K., Nakamura, T., Nicum, S., Nishio, S., Oliver, M., Ottevanger, P., Fidalgo, J. P., Pietzner, K., Pisano, C., Polterauer, S., Quesada, S., Raaschou-Jensen, N., Ramirez, P., Raspagliesi, F., Ray-Coquard, I., Sanchez, A. R., Regina, A., Diaz, R. R., Lagunes, M. R., Noguera, I. R., Rosengarten, O., Perez, M. J. R., Sabourin, J., Safra, T., Salazar, P., Salutari, V., Samouelian, V., Santin, A., Santin, A., Santoro, A., Santos-Reyes, L., Satoh, T., Secord, A., Selle, F., Sfakianos, G., Slomovitz, B., Soomers, V., Suzuki, S., Syrios, I., Takehara, K., Tang, J., Taylor, A., Tchabo, N., Tenney, M., Thaker, P., Tillmanns, T., Tlusty, V., Tognon, G., Tomao, F., Torkildsen, C., Trillsch, F., Tromp, J., Tuppurainen, M., Turco, L. C., Urbanski, B., Usami, T., Gorp, T. V., Velez-Cortes, H., Vera, K., Vistad, I., Vulsteke, C., Wampfler, J., Wan, Z. W. I., Wang, L., Wang, L., Wang, W., Wang, Y., Wang, Y., Watari, H., Wei, X., Weinberger, V., Willmott, L., Wimberger, P., Yamagami, W., Ruiz, E. Y., Yang, H., Yang, X., Yin, R., Yokom, D., Yonemori, K., Yuan, J., Yunokawa, M., Yusof, M. M., Zagouri, F., Zamagni, C., Zhang, B., Zhang, G., Zhang, J., Zhang, M., Zhang, Y., Zhang, Y., Zhu, G., Zhu, J., Zikan, M., & Zweizig, S. (2026). Sacituzumab tirumotecan versus treatment of physician's choice in previously treated endometrial cancer (TroFuse-005/ENGOT-en23/GOG-3095): a randomised, open-label, phase 3 trial. The Lancet. https://doi.org/10.1016/s0140-6736(26)02099-4