Niraparib in patients with metastatic castration-resistant prostate cancer and DNA repair gene defects (GALAHAD): a multicentre, open-label, phase 2 trial

Matthew R Smith, Howard I Scher, Shahneen Sandhu, Eleni Efstathiou, Primo N Lara, Evan Y Yu, Daniel J George, Kim N Chi, Fred Saad, Olof Ståhl, David Olmos, Daniel C Danila, Gary E Mason, Byron M Espina, Xin Zhao, Karen A Urtishak, Peter Francis, Angela Lopez-Gitlitz, Karim Fizazi, Francis Parnis, Anthony M. Joshua, Lisa G. Horvath, Christopher Steer, Gavin Marx, Shahneen Sandhu, Howard Gurney, Thomas Ferguson, Siska Van Bruwaene, Daisy Luyten, Peter Schatteman, Nicolaas Lumen, Luc Dirix, Jean-Charles Goeminne, Thierry Gil, Emmanuel Seront, Christof Vulsteke, Celio Kussumoto, Fabio A. Franke, Fabricio Augusto Martinelli de Oliveira, Andrea Juliana Pereira de Santana Gomes, Hélio Pinczowski, Daniel D'Almeida Preto, Luis Eduardo Zucca, Giuliano Santos Borges, Andre M. Murad, Fred Saad, Kim N. Chi, Yves Fradet, Neil E. Fleshner, Urban Emmenegger, Klaus Brasso, Karim Fizazi, Stephane Culine, Antoine Thiery-Vuillemin, Florence Joly, Aude Fléchon, Werner Hilgers, Jean-Christophe Eymard, Delphine Borchiellini, Philippe Barthélémy, Raanan Berger, Raya Leibowitz-Amit, Wilmosh Mermershtain, Keren Rouvinov, Avivit Peer, Svetlana Kovel, Avishay Sella, Martijn P. Lolkema, Alfonsus J.M. van den Eertwegh, Johannes Voortman, Maureen J. Aarts, Jourik A. Gietema, Choung-Soo Kim, Young-Deuk Choi, Byung-Ha Chung, Rustem A. Gafanov, Evgeniy Kopyltsov, Evgeny A. Usynin, Joan Carles, Begoña Mellado, José Pablo Maroto, Jesús García-Donás, Juan Francisco Rodríguez Moreno, Ignacio Durán, Begoña Pérez-Valderrama, Elena Castro, David Olmos, María José Méndez-Vidal, David Lorente Estellés, Regina Gironés Sarrió, José Muñoz-Langa, Urbano Anido Herranz, Javier Puente Vázquez, Enrique Castellanos, Martin Hellström, Anders Widmark, Ingela Franck Lissbrant, Åsa Jellvert, Cecilia Külich, René Blom, Olof Ståhl, Po-Hui Chiang, Chih-Hsiung Kang, Yen-Chuan Ou, Shian-Shiang Wang, Hsi-Chin Wu, Yu-Chuan Lu, Gerhardt Attard, Vincent Khoo, Amit Bahl, Prasad Kellati, Omi Parikh, Rajaguru Srinivasan, Jason F. Lester, John N. Staffurth, Heather H. Cheng, Eleni Efstathiou, Patrick G. Pilié, Daniel J. George, Lawrence I. Karsh, W. Kevin Kelly, Daniel C. Danila, Paul R. Sieber, Matthew R. Smith, Elisabeth I. Heath, Ulka N. Vaishampayan, Thomas W. Flaig, Hamid Emamekhoo, Jacek K. Pinski, Arash Rezazadeh Kalebasty, Joseph J. Maly, Helen Moon

Open source

DOI
10.1016/s1470-2045(21)00757-9
Published
2022-03
Container
The Lancet Oncology
Publisher
Elsevier BV
Open access
unknown

Credibility signals

uncertain Score 64/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

Cite this work

BibTeX

@article{allodium:10.1016/s1470-2045-21-00757-9,
  title = {Niraparib in patients with metastatic castration-resistant prostate cancer and DNA repair gene defects (GALAHAD): a multicentre, open-label, phase 2 trial},
  author = {Matthew R Smith and Howard I Scher and Shahneen Sandhu and Eleni Efstathiou and Primo N Lara and Evan Y Yu and Daniel J George and Kim N Chi and Fred Saad and Olof Ståhl and David Olmos and Daniel C Danila and Gary E Mason and Byron M Espina and Xin Zhao and Karen A Urtishak and Peter Francis and Angela Lopez-Gitlitz and Karim Fizazi and Francis Parnis and Anthony M. Joshua and Lisa G. Horvath and Christopher Steer and Gavin Marx and Shahneen Sandhu and Howard Gurney and Thomas Ferguson and Siska Van Bruwaene and Daisy Luyten and Peter Schatteman and Nicolaas Lumen and Luc Dirix and Jean-Charles Goeminne and Thierry Gil and Emmanuel Seront and Christof Vulsteke and Celio Kussumoto and Fabio A. Franke and Fabricio Augusto Martinelli de Oliveira and Andrea Juliana Pereira de Santana Gomes and Hélio Pinczowski and Daniel D'Almeida Preto and Luis Eduardo Zucca and Giuliano Santos Borges and Andre M. Murad and Fred Saad and Kim N. Chi and Yves Fradet and Neil E. Fleshner and Urban Emmenegger and Klaus Brasso and Karim Fizazi and Stephane Culine and Antoine Thiery-Vuillemin and Florence Joly and Aude Fléchon and Werner Hilgers and Jean-Christophe Eymard and Delphine Borchiellini and Philippe Barthélémy and Raanan Berger and Raya Leibowitz-Amit and Wilmosh Mermershtain and Keren Rouvinov and Avivit Peer and Svetlana Kovel and Avishay Sella and Martijn P. Lolkema and Alfonsus J.M. van den Eertwegh and Johannes Voortman and Maureen J. Aarts and Jourik A. Gietema and Choung-Soo Kim and Young-Deuk Choi and Byung-Ha Chung and Rustem A. Gafanov and Evgeniy Kopyltsov and Evgeny A. Usynin and Joan Carles and Begoña Mellado and José Pablo Maroto and Jesús García-Donás and Juan Francisco Rodríguez Moreno and Ignacio Durán and Begoña Pérez-Valderrama and Elena Castro and David Olmos and María José Méndez-Vidal and David Lorente Estellés and Regina Gironés Sarrió and José Muñoz-Langa and Urbano Anido Herranz and Javier Puente Vázquez and Enrique Castellanos and Martin Hellström and Anders Widmark and Ingela Franck Lissbrant and Åsa Jellvert and Cecilia Külich and René Blom and Olof Ståhl and Po-Hui Chiang and Chih-Hsiung Kang and Yen-Chuan Ou and Shian-Shiang Wang and Hsi-Chin Wu and Yu-Chuan Lu and Gerhardt Attard and Vincent Khoo and Amit Bahl and Prasad Kellati and Omi Parikh and Rajaguru Srinivasan and Jason F. Lester and John N. Staffurth and Heather H. Cheng and Eleni Efstathiou and Patrick G. Pilié and Daniel J. George and Lawrence I. Karsh and W. Kevin Kelly and Daniel C. Danila and Paul R. Sieber and Matthew R. Smith and Elisabeth I. Heath and Ulka N. Vaishampayan and Thomas W. Flaig and Hamid Emamekhoo and Jacek K. Pinski and Arash Rezazadeh Kalebasty and Joseph J. Maly and Helen Moon},
  year = {2022},
  journal = {The Lancet Oncology},
  doi = {10.1016/s1470-2045(21)00757-9},
  url = {https://doi.org/10.1016/s1470-2045(21)00757-9}
}

RIS

TY  - JOUR
TI  - Niraparib in patients with metastatic castration-resistant prostate cancer and DNA repair gene defects (GALAHAD): a multicentre, open-label, phase 2 trial
AU  - Matthew R Smith
AU  - Howard I Scher
AU  - Shahneen Sandhu
AU  - Eleni Efstathiou
AU  - Primo N Lara
AU  - Evan Y Yu
AU  - Daniel J George
AU  - Kim N Chi
AU  - Fred Saad
AU  - Olof Ståhl
AU  - David Olmos
AU  - Daniel C Danila
AU  - Gary E Mason
AU  - Byron M Espina
AU  - Xin Zhao
AU  - Karen A Urtishak
AU  - Peter Francis
AU  - Angela Lopez-Gitlitz
AU  - Karim Fizazi
AU  - Francis Parnis
AU  - Anthony M. Joshua
AU  - Lisa G. Horvath
AU  - Christopher Steer
AU  - Gavin Marx
AU  - Shahneen Sandhu
AU  - Howard Gurney
AU  - Thomas Ferguson
AU  - Siska Van Bruwaene
AU  - Daisy Luyten
AU  - Peter Schatteman
AU  - Nicolaas Lumen
AU  - Luc Dirix
AU  - Jean-Charles Goeminne
AU  - Thierry Gil
AU  - Emmanuel Seront
AU  - Christof Vulsteke
AU  - Celio Kussumoto
AU  - Fabio A. Franke
AU  - Fabricio Augusto Martinelli de Oliveira
AU  - Andrea Juliana Pereira de Santana Gomes
AU  - Hélio Pinczowski
AU  - Daniel D'Almeida Preto
AU  - Luis Eduardo Zucca
AU  - Giuliano Santos Borges
AU  - Andre M. Murad
AU  - Fred Saad
AU  - Kim N. Chi
AU  - Yves Fradet
AU  - Neil E. Fleshner
AU  - Urban Emmenegger
AU  - Klaus Brasso
AU  - Karim Fizazi
AU  - Stephane Culine
AU  - Antoine Thiery-Vuillemin
AU  - Florence Joly
AU  - Aude Fléchon
AU  - Werner Hilgers
AU  - Jean-Christophe Eymard
AU  - Delphine Borchiellini
AU  - Philippe Barthélémy
AU  - Raanan Berger
AU  - Raya Leibowitz-Amit
AU  - Wilmosh Mermershtain
AU  - Keren Rouvinov
AU  - Avivit Peer
AU  - Svetlana Kovel
AU  - Avishay Sella
AU  - Martijn P. Lolkema
AU  - Alfonsus J.M. van den Eertwegh
AU  - Johannes Voortman
AU  - Maureen J. Aarts
AU  - Jourik A. Gietema
AU  - Choung-Soo Kim
AU  - Young-Deuk Choi
AU  - Byung-Ha Chung
AU  - Rustem A. Gafanov
AU  - Evgeniy Kopyltsov
AU  - Evgeny A. Usynin
AU  - Joan Carles
AU  - Begoña Mellado
AU  - José Pablo Maroto
AU  - Jesús García-Donás
AU  - Juan Francisco Rodríguez Moreno
AU  - Ignacio Durán
AU  - Begoña Pérez-Valderrama
AU  - Elena Castro
AU  - David Olmos
AU  - María José Méndez-Vidal
AU  - David Lorente Estellés
AU  - Regina Gironés Sarrió
AU  - José Muñoz-Langa
AU  - Urbano Anido Herranz
AU  - Javier Puente Vázquez
AU  - Enrique Castellanos
AU  - Martin Hellström
AU  - Anders Widmark
AU  - Ingela Franck Lissbrant
AU  - Åsa Jellvert
AU  - Cecilia Külich
AU  - René Blom
AU  - Olof Ståhl
AU  - Po-Hui Chiang
AU  - Chih-Hsiung Kang
AU  - Yen-Chuan Ou
AU  - Shian-Shiang Wang
AU  - Hsi-Chin Wu
AU  - Yu-Chuan Lu
AU  - Gerhardt Attard
AU  - Vincent Khoo
AU  - Amit Bahl
AU  - Prasad Kellati
AU  - Omi Parikh
AU  - Rajaguru Srinivasan
AU  - Jason F. Lester
AU  - John N. Staffurth
AU  - Heather H. Cheng
AU  - Eleni Efstathiou
AU  - Patrick G. Pilié
AU  - Daniel J. George
AU  - Lawrence I. Karsh
AU  - W. Kevin Kelly
AU  - Daniel C. Danila
AU  - Paul R. Sieber
AU  - Matthew R. Smith
AU  - Elisabeth I. Heath
AU  - Ulka N. Vaishampayan
AU  - Thomas W. Flaig
AU  - Hamid Emamekhoo
AU  - Jacek K. Pinski
AU  - Arash Rezazadeh Kalebasty
AU  - Joseph J. Maly
AU  - Helen Moon
PY  - 2022
JO  - The Lancet Oncology
DO  - 10.1016/s1470-2045(21)00757-9
UR  - https://doi.org/10.1016/s1470-2045(21)00757-9
ER  - 

APA

Smith, M. R., Scher, H. I., Sandhu, S., Efstathiou, E., Lara, P. N., Yu, E. Y., George, D. J., Chi, K. N., Saad, F., Ståhl, O., Olmos, D., Danila, D. C., Mason, G. E., Espina, B. M., Zhao, X., Urtishak, K. A., Francis, P., Lopez-Gitlitz, A., Fizazi, K., Parnis, F., Joshua, A. M., Horvath, L. G., Steer, C., Marx, G., Sandhu, S., Gurney, H., Ferguson, T., Bruwaene, S. V., Luyten, D., Schatteman, P., Lumen, N., Dirix, L., Goeminne, J., Gil, T., Seront, E., Vulsteke, C., Kussumoto, C., Franke, F. A., Oliveira, F. A. M. D., Gomes, A. J. P. D. S., Pinczowski, H., Preto, D. D., Zucca, L. E., Borges, G. S., Murad, A. M., Saad, F., Chi, K. N., Fradet, Y., Fleshner, N. E., Emmenegger, U., Brasso, K., Fizazi, K., Culine, S., Thiery-Vuillemin, A., Joly, F., Fléchon, A., Hilgers, W., Eymard, J., Borchiellini, D., Barthélémy, P., Berger, R., Leibowitz-Amit, R., Mermershtain, W., Rouvinov, K., Peer, A., Kovel, S., Sella, A., Lolkema, M. P., Eertwegh, A. J. V. D., Voortman, J., Aarts, M. J., Gietema, J. A., Kim, C., Choi, Y., Chung, B., Gafanov, R. A., Kopyltsov, E., Usynin, E. A., Carles, J., Mellado, B., Maroto, J. P., García-Donás, J., Moreno, J. F. R., Durán, I., Pérez-Valderrama, B., Castro, E., Olmos, D., Méndez-Vidal, M. J., Estellés, D. L., Sarrió, R. G., Muñoz-Langa, J., Herranz, U. A., Vázquez, J. P., Castellanos, E., Hellström, M., Widmark, A., Lissbrant, I. F., Jellvert, Å., Külich, C., Blom, R., Ståhl, O., Chiang, P., Kang, C., Ou, Y., Wang, S., Wu, H., Lu, Y., Attard, G., Khoo, V., Bahl, A., Kellati, P., Parikh, O., Srinivasan, R., Lester, J. F., Staffurth, J. N., Cheng, H. H., Efstathiou, E., Pilié, P. G., George, D. J., Karsh, L. I., Kelly, W. K., Danila, D. C., Sieber, P. R., Smith, M. R., Heath, E. I., Vaishampayan, U. N., Flaig, T. W., Emamekhoo, H., Pinski, J. K., Kalebasty, A. R., Maly, J. J., & Moon, H. (2022). Niraparib in patients with metastatic castration-resistant prostate cancer and DNA repair gene defects (GALAHAD): a multicentre, open-label, phase 2 trial. The Lancet Oncology. https://doi.org/10.1016/s1470-2045(21)00757-9

Source records