Pembrolizumab plus chemotherapy versus placebo plus chemotherapy for HER2-negative advanced gastric cancer (KEYNOTE-859): a multicentre, randomised, double-blind, phase 3 trial

BibTeX

@article{allodium:10.1016/s1470-2045-23-00515-6,
  title = {Pembrolizumab plus chemotherapy versus placebo plus chemotherapy for HER2-negative advanced gastric cancer (KEYNOTE-859): a multicentre, randomised, double-blind, phase 3 trial},
  author = {Sun Young Rha and Do-Youn Oh and Patricio Yañez and Yuxian Bai and Min-Hee Ryu and Jeeyun Lee and Fernando Rivera and Gustavo Vasconcelos Alves and Marcelo Garrido and Kai-Keen Shiu and Manuel González Fernández and Jin Li and Maeve A Lowery and Timuçin Çil and Felipe Melo Cruz and Shukui Qin and Suxia Luo and Hongming Pan and Zev A Wainberg and Lina Yin and Sonal Bordia and Pooja Bhagia and Lucjan S Wyrwicz and Guillermo Mendez and Juan Manuel O'Connor and Alvaro Yanzi Castilla and Juan Cundom and Diego Kaen and Rachel Wong and Weng Ng and Morteza Aghmesheh and Mauricio Peressoni and Carlos Andrade and Fabio Franke and Gustavo Alves and Felipe Jose Cruz and Karina Vianna and Maria Marcela Monteiro and Michael Raphael and Scott Berry and Raymond Jang and Ann Tan and Jamil Asselah and Patricio Yanez Weber and Mauricio Mahave and Cesar Sanchez and Pamela Salman and Yuxian Bai and Jin Li and Xiaochun Zhang and Tianshu Liu and Xiaoyan Lin and Shukui Qin and Jianwei Yang and Suxia Luo and Wei Li and Jieer Ying and Xi Chen and Shan Zeng and Yanli Qu and Lin Yang and Lin Zhao and Ping Chen and Hongming Pan and Enxiao Li and Feng Ye and Jianwei Lu and Xinjun Liang and Qun Zhao and Xianli Yin and Junhe Li and Yang Ling and Guoqing Lv and Shouguo Li and Alvaro Guerrero and Juan Rubiano and Manuel Gonzalez Fernandez and Ray Manneh Kopp and Adrian Guzman Ramirez and Luis Corrales and Ileana Gonzalez Herrera and Bohuslav Melichar and Tomas Buchler and Tomas Svoboda and Radka Obermannova and David Vrana and Jakub Cvek and Per Pfeiffer and Lene Baeksgaard and Mette Yilmaz and Valerie Boige and Daniel Lopez-Trabada and Christophe Borg and Diane Pannier and Sandrine Hiret and Frederic Di Fiore and Jean-Philippe Metges and Dirk Arnold and Uwe Martens and Florian Lordick and Alexander Stein and Hugo Castro and Karla Lopez and Julio Ramirez and Mynor Aguilar and Marco Chivalan and Wendy Chan and Ashley Cheng and Winnie Yeo and Peter Arkosy and Tibor Csoszi and Erika Hitre and Zsolt Horvath and Maeve Lowery and Ray McDermott and Patrick Morris and Ayala Hubert and Baruch Brenner and Irit Ben-Aharon and Einat Shacham-Shmueli and Sofia Man and Sharon Pelles Avraham and Ronen Brenner and Moshe Mishaeli and Maria Di Bartolomeo and Nicola Fazio and Sara Lonardi and Carlo Garufi and Taroh Satoh and Hiroki Hara and Shiro Iwagami and Hisateru Yasui and Masahiro Tsuda and Tatsu Shimoyama and Hirokazu Shoji and Naotoshi Sugimoto and Nobuhiro Shibata and Kensei Yamaguchi and Kenji Amagai and Yasuhiro Choda and Taito Esaki and Hiroshi Yabusaki and Takashi Oshima and Akihito Tsuji and Hisato Kawakami and Akihito Kawazoe and Kenji Ishido and Shigenori Kadowaki and Jorge Martinez Rodriguez and Marytere Herrera Martinez and Fidel Huitzil Melendez and Francisco Ramirez Godinez and Paola Balancan and Dragan Damianovich and Victor Castro Oliden and Julio Grados and Cesar Torres and Lucjan Wyrwicz and Piotr Wysocki and Lukasz Hajac and Jakub Zolnierek and Boguslawa Karaszewska and Sun Young Rha and Jeeyun Lee and Min-Hee Ryu and Do-Youn Oh and Rashida Orlova and Sergey Tjulandin and Natalia Fadeeva and Yulia Makarycheva and Dmitry Nosov and Maria Smagina and Sze Chan and Conrad Jacobs and Peter Kraus and Gregory Landers and Barbara Robertson and Paul Ruff and Elizabeth Schoeman and Jean-Marc Maurel and Marc Diez Garcia and Paula Jimenez Fonseca and Javier Gallego Plazas and Fernando Rivera Herrero and Jesus Miranda Poma and Laura Layos Romero and Ralph Fritsch and Sara Bastian and Ralph Winterhalder and Sara De Dosso and Thibaud Kossler and Kun-Huei Yeh and Chia-Jui Yen and Yen-Yang Chen and Johnson Lin and Mehmet Bilici and Mustafa Ozguroglu and Timucin Cil and Berna Oksuzoglu and Hakan Harputluoglu and Aziz Karaoglu and Ilhan Hacibekiroglu and Bulent Erdogan and Suayib Yalcin and Hryhoriy Adamchuk and Igor Bondarenko and Oleksii Kolesnik and Yuriy Ostapenko and Anna Kryzhanivska and Lurii Leshchenko and Ievgen Ilin and Yaroslav Shparyk and Dmytro Trukhin and Nataliia Voitko and Rajarshi Roy and Anna-Mary Young and Louise Medley and Kai-Keen Shiu and Paul Celano and Lindsay Overton and Moses Raj and Richard Dunne and Zev Wainberg and Farshid Dayyani and Timothy Larson and Mark Kochenderfer},
  year = {2023},
  journal = {The Lancet Oncology},
  doi = {10.1016/s1470-2045(23)00515-6},
  url = {https://doi.org/10.1016/s1470-2045(23)00515-6}
}

RIS

TY  - JOUR
TI  - Pembrolizumab plus chemotherapy versus placebo plus chemotherapy for HER2-negative advanced gastric cancer (KEYNOTE-859): a multicentre, randomised, double-blind, phase 3 trial
AU  - Sun Young Rha
AU  - Do-Youn Oh
AU  - Patricio Yañez
AU  - Yuxian Bai
AU  - Min-Hee Ryu
AU  - Jeeyun Lee
AU  - Fernando Rivera
AU  - Gustavo Vasconcelos Alves
AU  - Marcelo Garrido
AU  - Kai-Keen Shiu
AU  - Manuel González Fernández
AU  - Jin Li
AU  - Maeve A Lowery
AU  - Timuçin Çil
AU  - Felipe Melo Cruz
AU  - Shukui Qin
AU  - Suxia Luo
AU  - Hongming Pan
AU  - Zev A Wainberg
AU  - Lina Yin
AU  - Sonal Bordia
AU  - Pooja Bhagia
AU  - Lucjan S Wyrwicz
AU  - Guillermo Mendez
AU  - Juan Manuel O'Connor
AU  - Alvaro Yanzi Castilla
AU  - Juan Cundom
AU  - Diego Kaen
AU  - Rachel Wong
AU  - Weng Ng
AU  - Morteza Aghmesheh
AU  - Mauricio Peressoni
AU  - Carlos Andrade
AU  - Fabio Franke
AU  - Gustavo Alves
AU  - Felipe Jose Cruz
AU  - Karina Vianna
AU  - Maria Marcela Monteiro
AU  - Michael Raphael
AU  - Scott Berry
AU  - Raymond Jang
AU  - Ann Tan
AU  - Jamil Asselah
AU  - Patricio Yanez Weber
AU  - Mauricio Mahave
AU  - Cesar Sanchez
AU  - Pamela Salman
AU  - Yuxian Bai
AU  - Jin Li
AU  - Xiaochun Zhang
AU  - Tianshu Liu
AU  - Xiaoyan Lin
AU  - Shukui Qin
AU  - Jianwei Yang
AU  - Suxia Luo
AU  - Wei Li
AU  - Jieer Ying
AU  - Xi Chen
AU  - Shan Zeng
AU  - Yanli Qu
AU  - Lin Yang
AU  - Lin Zhao
AU  - Ping Chen
AU  - Hongming Pan
AU  - Enxiao Li
AU  - Feng Ye
AU  - Jianwei Lu
AU  - Xinjun Liang
AU  - Qun Zhao
AU  - Xianli Yin
AU  - Junhe Li
AU  - Yang Ling
AU  - Guoqing Lv
AU  - Shouguo Li
AU  - Alvaro Guerrero
AU  - Juan Rubiano
AU  - Manuel Gonzalez Fernandez
AU  - Ray Manneh Kopp
AU  - Adrian Guzman Ramirez
AU  - Luis Corrales
AU  - Ileana Gonzalez Herrera
AU  - Bohuslav Melichar
AU  - Tomas Buchler
AU  - Tomas Svoboda
AU  - Radka Obermannova
AU  - David Vrana
AU  - Jakub Cvek
AU  - Per Pfeiffer
AU  - Lene Baeksgaard
AU  - Mette Yilmaz
AU  - Valerie Boige
AU  - Daniel Lopez-Trabada
AU  - Christophe Borg
AU  - Diane Pannier
AU  - Sandrine Hiret
AU  - Frederic Di Fiore
AU  - Jean-Philippe Metges
AU  - Dirk Arnold
AU  - Uwe Martens
AU  - Florian Lordick
AU  - Alexander Stein
AU  - Hugo Castro
AU  - Karla Lopez
AU  - Julio Ramirez
AU  - Mynor Aguilar
AU  - Marco Chivalan
AU  - Wendy Chan
AU  - Ashley Cheng
AU  - Winnie Yeo
AU  - Peter Arkosy
AU  - Tibor Csoszi
AU  - Erika Hitre
AU  - Zsolt Horvath
AU  - Maeve Lowery
AU  - Ray McDermott
AU  - Patrick Morris
AU  - Ayala Hubert
AU  - Baruch Brenner
AU  - Irit Ben-Aharon
AU  - Einat Shacham-Shmueli
AU  - Sofia Man
AU  - Sharon Pelles Avraham
AU  - Ronen Brenner
AU  - Moshe Mishaeli
AU  - Maria Di Bartolomeo
AU  - Nicola Fazio
AU  - Sara Lonardi
AU  - Carlo Garufi
AU  - Taroh Satoh
AU  - Hiroki Hara
AU  - Shiro Iwagami
AU  - Hisateru Yasui
AU  - Masahiro Tsuda
AU  - Tatsu Shimoyama
AU  - Hirokazu Shoji
AU  - Naotoshi Sugimoto
AU  - Nobuhiro Shibata
AU  - Kensei Yamaguchi
AU  - Kenji Amagai
AU  - Yasuhiro Choda
AU  - Taito Esaki
AU  - Hiroshi Yabusaki
AU  - Takashi Oshima
AU  - Akihito Tsuji
AU  - Hisato Kawakami
AU  - Akihito Kawazoe
AU  - Kenji Ishido
AU  - Shigenori Kadowaki
AU  - Jorge Martinez Rodriguez
AU  - Marytere Herrera Martinez
AU  - Fidel Huitzil Melendez
AU  - Francisco Ramirez Godinez
AU  - Paola Balancan
AU  - Dragan Damianovich
AU  - Victor Castro Oliden
AU  - Julio Grados
AU  - Cesar Torres
AU  - Lucjan Wyrwicz
AU  - Piotr Wysocki
AU  - Lukasz Hajac
AU  - Jakub Zolnierek
AU  - Boguslawa Karaszewska
AU  - Sun Young Rha
AU  - Jeeyun Lee
AU  - Min-Hee Ryu
AU  - Do-Youn Oh
AU  - Rashida Orlova
AU  - Sergey Tjulandin
AU  - Natalia Fadeeva
AU  - Yulia Makarycheva
AU  - Dmitry Nosov
AU  - Maria Smagina
AU  - Sze Chan
AU  - Conrad Jacobs
AU  - Peter Kraus
AU  - Gregory Landers
AU  - Barbara Robertson
AU  - Paul Ruff
AU  - Elizabeth Schoeman
AU  - Jean-Marc Maurel
AU  - Marc Diez Garcia
AU  - Paula Jimenez Fonseca
AU  - Javier Gallego Plazas
AU  - Fernando Rivera Herrero
AU  - Jesus Miranda Poma
AU  - Laura Layos Romero
AU  - Ralph Fritsch
AU  - Sara Bastian
AU  - Ralph Winterhalder
AU  - Sara De Dosso
AU  - Thibaud Kossler
AU  - Kun-Huei Yeh
AU  - Chia-Jui Yen
AU  - Yen-Yang Chen
AU  - Johnson Lin
AU  - Mehmet Bilici
AU  - Mustafa Ozguroglu
AU  - Timucin Cil
AU  - Berna Oksuzoglu
AU  - Hakan Harputluoglu
AU  - Aziz Karaoglu
AU  - Ilhan Hacibekiroglu
AU  - Bulent Erdogan
AU  - Suayib Yalcin
AU  - Hryhoriy Adamchuk
AU  - Igor Bondarenko
AU  - Oleksii Kolesnik
AU  - Yuriy Ostapenko
AU  - Anna Kryzhanivska
AU  - Lurii Leshchenko
AU  - Ievgen Ilin
AU  - Yaroslav Shparyk
AU  - Dmytro Trukhin
AU  - Nataliia Voitko
AU  - Rajarshi Roy
AU  - Anna-Mary Young
AU  - Louise Medley
AU  - Kai-Keen Shiu
AU  - Paul Celano
AU  - Lindsay Overton
AU  - Moses Raj
AU  - Richard Dunne
AU  - Zev Wainberg
AU  - Farshid Dayyani
AU  - Timothy Larson
AU  - Mark Kochenderfer
PY  - 2023
JO  - The Lancet Oncology
DO  - 10.1016/s1470-2045(23)00515-6
UR  - https://doi.org/10.1016/s1470-2045(23)00515-6
ER  - 

APA

Rha, S. Y., Oh, D., Yañez, P., Bai, Y., Ryu, M., Lee, J., Rivera, F., Alves, G. V., Garrido, M., Shiu, K., Fernández, M. G., Li, J., Lowery, M. A., Çil, T., Cruz, F. M., Qin, S., Luo, S., Pan, H., Wainberg, Z. A., Yin, L., Bordia, S., Bhagia, P., Wyrwicz, L. S., Mendez, G., O'Connor, J. M., Castilla, A. Y., Cundom, J., Kaen, D., Wong, R., Ng, W., Aghmesheh, M., Peressoni, M., Andrade, C., Franke, F., Alves, G., Cruz, F. J., Vianna, K., Monteiro, M. M., Raphael, M., Berry, S., Jang, R., Tan, A., Asselah, J., Weber, P. Y., Mahave, M., Sanchez, C., Salman, P., Bai, Y., Li, J., Zhang, X., Liu, T., Lin, X., Qin, S., Yang, J., Luo, S., Li, W., Ying, J., Chen, X., Zeng, S., Qu, Y., Yang, L., Zhao, L., Chen, P., Pan, H., Li, E., Ye, F., Lu, J., Liang, X., Zhao, Q., Yin, X., Li, J., Ling, Y., Lv, G., Li, S., Guerrero, A., Rubiano, J., Fernandez, M. G., Kopp, R. M., Ramirez, A. G., Corrales, L., Herrera, I. G., Melichar, B., Buchler, T., Svoboda, T., Obermannova, R., Vrana, D., Cvek, J., Pfeiffer, P., Baeksgaard, L., Yilmaz, M., Boige, V., Lopez-Trabada, D., Borg, C., Pannier, D., Hiret, S., Fiore, F. D., Metges, J., Arnold, D., Martens, U., Lordick, F., Stein, A., Castro, H., Lopez, K., Ramirez, J., Aguilar, M., Chivalan, M., Chan, W., Cheng, A., Yeo, W., Arkosy, P., Csoszi, T., Hitre, E., Horvath, Z., Lowery, M., McDermott, R., Morris, P., Hubert, A., Brenner, B., Ben-Aharon, I., Shacham-Shmueli, E., Man, S., Avraham, S. P., Brenner, R., Mishaeli, M., Bartolomeo, M. D., Fazio, N., Lonardi, S., Garufi, C., Satoh, T., Hara, H., Iwagami, S., Yasui, H., Tsuda, M., Shimoyama, T., Shoji, H., Sugimoto, N., Shibata, N., Yamaguchi, K., Amagai, K., Choda, Y., Esaki, T., Yabusaki, H., Oshima, T., Tsuji, A., Kawakami, H., Kawazoe, A., Ishido, K., Kadowaki, S., Rodriguez, J. M., Martinez, M. H., Melendez, F. H., Godinez, F. R., Balancan, P., Damianovich, D., Oliden, V. C., Grados, J., Torres, C., Wyrwicz, L., Wysocki, P., Hajac, L., Zolnierek, J., Karaszewska, B., Rha, S. Y., Lee, J., Ryu, M., Oh, D., Orlova, R., Tjulandin, S., Fadeeva, N., Makarycheva, Y., Nosov, D., Smagina, M., Chan, S., Jacobs, C., Kraus, P., Landers, G., Robertson, B., Ruff, P., Schoeman, E., Maurel, J., Garcia, M. D., Fonseca, P. J., Plazas, J. G., Herrero, F. R., Poma, J. M., Romero, L. L., Fritsch, R., Bastian, S., Winterhalder, R., Dosso, S. D., Kossler, T., Yeh, K., Yen, C., Chen, Y., Lin, J., Bilici, M., Ozguroglu, M., Cil, T., Oksuzoglu, B., Harputluoglu, H., Karaoglu, A., Hacibekiroglu, I., Erdogan, B., Yalcin, S., Adamchuk, H., Bondarenko, I., Kolesnik, O., Ostapenko, Y., Kryzhanivska, A., Leshchenko, L., Ilin, I., Shparyk, Y., Trukhin, D., Voitko, N., Roy, R., Young, A., Medley, L., Shiu, K., Celano, P., Overton, L., Raj, M., Dunne, R., Wainberg, Z., Dayyani, F., Larson, T., & Kochenderfer, M. (2023). Pembrolizumab plus chemotherapy versus placebo plus chemotherapy for HER2-negative advanced gastric cancer (KEYNOTE-859): a multicentre, randomised, double-blind, phase 3 trial. The Lancet Oncology. https://doi.org/10.1016/s1470-2045(23)00515-6