Safety and efficacy of zilucoplan in patients with generalised myasthenia gravis (RAISE): a randomised, double-blind, placebo-controlled, phase 3 study

BibTeX

@article{allodium:10.1016/s1474-4422-23-00080-7,
  title = {Safety and efficacy of zilucoplan in patients with generalised myasthenia gravis (RAISE): a randomised, double-blind, placebo-controlled, phase 3 study},
  author = {James F Howard and Saskia Bresch and Angela Genge and Channa Hewamadduma and John Hinton and Yessar Hussain and Raul Juntas-Morales and Henry J Kaminski and Angelina Maniaol and Renato Mantegazza and Masayuki Masuda and Kumaraswamy Sivakumar and Marek Śmiłowski and Kimiaki Utsugisawa and Tuan Vu and Michael D Weiss and Małgorzata Zajda and Babak Boroojerdi and Melissa Brock and Guillemette de la Borderie and Petra W Duda and Romana Lowcock and Mark Vanderkelen and M Isabel Leite and Dylan Sembinelli and Jeanne Teitelbaum and Michael Nicolle and Emilien Bernard and Juliette Svahn and Marco Spinazzi and Tanya Stojkovic and Sophie Demeret and Nicolas Weiss and Loïc Le Guennec and Sihame Messai and Christine Tranchant and Aleksandra Nadaj-Pakleza and Jean-Baptiste Chanson and Muhtadi Suliman and Leila Zaidi and Celine Tard and Peggy Lecointe and Jana Zschüntzsch and Jens Schmidt and Stefanie Glaubitz and Rachel Zeng and Matthias Scholl and Markus Kowarik and Ulf Ziemann and Markus Krumbholz and Pascal Martin and Christoph Ruschil and Jutta Dünschede and Roswitha Kemmner and Natalie Rumpel and Benjamin Berger and Andreas Totzeck and Tim Hagenacker and Benjamin Stolte and Raffaele Iorio and Amelia Evoli and Silvia Falso and Carlo Antozzi and Rita Frangiamore and Fiammetta Vanoli and Elena Rinaldi and Kazushi Deguchi and Naoya Minami and Yuriko Nagane and Yasushi Suzuki and Sayaka Ishida and Shigeaki Suzuki and Jin Nakahara and Astushi Nagaoka and Shunsuke Yoshimura and Shingo Konno and Youko Tsuya and Akiyuki Uzawa and Tomoya Kubota and Masanori Takahashi and Tatsusada Okuno and Hiroyuki Murai and Nils Erik Gilhus and Marion Boldingh and Tone Hakvåg Rønning and Urszula Chyrchel-Paszkiewicz and Klaudiusz Kumor and Tomasz Zielinski and Krzysztof Banaszkiewicz and Michał Błaż and Agata Kłósek and Mariola Świderek-Matysiak and Andrzej Szczudlik and Aneta Paśko and Lech Szczechowski and Marta Banach and Jan Ilkowski and Solange Kapetanovic Garcia and Patricia Ortiz Bagan and Ana Belén Cánovas Segura and Joana Turon Sans and Nuria Vidal Fernandez and Elena Cortes Vicente and Patricia Rodrigo Armenteros and Mohammad Ashraghi and Ana Cavey and Liam Haslam and Anna Emery and Kore Liow and Sharon Yegiaian and Alexandru Barboi and Rosa Maria Vazquez and Joshua Lennon and Robert M Pascuzzi and Cynthia Bodkin and Sandra Guingrich and Adam Comer and Mark Bromberg and Teresa Janecki and Sami Saba and Marco Tellez and Bakri Elsheikh and Miriam Freimer and Sarah Heintzman and Raghav Govindarajan and Jeffrey Guptill and Janice M Massey and Vern Juel and Natalia Gonzalez and Ali A Habib and Tahseen Mozaffar and Manisha Korb and Namita Goyal and Hannah Machemehl and Georgios Manousakis and Jeffrey Allen and Emily Harper and Constantine Farmakidis and Lilli Saavedra and Mazen Dimachkie and Mamatha Pasnoor and Salma Akhter and Said Beydoun and Courtney McIlduff and Joan Nye and Bhaskar Roy and Bailey Munro Sheldon and Richard Nowak and Benjamin Barnes and Michael Rivner and Niraja Suresh and Jessica Shaw and Brittany Harvey and Lucy Lam and Nikki Thomas and Manisha Chopra and Rebecca E Traub and Sarah Jones and Mary Wagoner and Sejla Smajic and Radwa Aly and Jonathan Katz and Henry Chen and Robert G Miller and Liberty Jenkins and Shaida Khan and Bhupendra Khatri and Lisa Sershon and Pantelis Pavlakis and Shara Holzberg and Yuebing Li and Irys B Caristo and Robert Marquardt and Debbie Hastings and Jacob Rube and Robert P Lisak and Aparna Choudhury and Katherine Ruzhansky and Amit Sachdev and Susan Shin and Joan Bratton and Mary Fetter and Naya McKinnon and Jonathan McKinnon and Laura Sissons-Ross and Amos Sahu and B Jane Distad},
  year = {2023},
  journal = {The Lancet Neurology},
  doi = {10.1016/s1474-4422(23)00080-7},
  url = {https://doi.org/10.1016/s1474-4422(23)00080-7}
}

RIS

TY  - JOUR
TI  - Safety and efficacy of zilucoplan in patients with generalised myasthenia gravis (RAISE): a randomised, double-blind, placebo-controlled, phase 3 study
AU  - James F Howard
AU  - Saskia Bresch
AU  - Angela Genge
AU  - Channa Hewamadduma
AU  - John Hinton
AU  - Yessar Hussain
AU  - Raul Juntas-Morales
AU  - Henry J Kaminski
AU  - Angelina Maniaol
AU  - Renato Mantegazza
AU  - Masayuki Masuda
AU  - Kumaraswamy Sivakumar
AU  - Marek Śmiłowski
AU  - Kimiaki Utsugisawa
AU  - Tuan Vu
AU  - Michael D Weiss
AU  - Małgorzata Zajda
AU  - Babak Boroojerdi
AU  - Melissa Brock
AU  - Guillemette de la Borderie
AU  - Petra W Duda
AU  - Romana Lowcock
AU  - Mark Vanderkelen
AU  - M Isabel Leite
AU  - Dylan Sembinelli
AU  - Jeanne Teitelbaum
AU  - Michael Nicolle
AU  - Emilien Bernard
AU  - Juliette Svahn
AU  - Marco Spinazzi
AU  - Tanya Stojkovic
AU  - Sophie Demeret
AU  - Nicolas Weiss
AU  - Loïc Le Guennec
AU  - Sihame Messai
AU  - Christine Tranchant
AU  - Aleksandra Nadaj-Pakleza
AU  - Jean-Baptiste Chanson
AU  - Muhtadi Suliman
AU  - Leila Zaidi
AU  - Celine Tard
AU  - Peggy Lecointe
AU  - Jana Zschüntzsch
AU  - Jens Schmidt
AU  - Stefanie Glaubitz
AU  - Rachel Zeng
AU  - Matthias Scholl
AU  - Markus Kowarik
AU  - Ulf Ziemann
AU  - Markus Krumbholz
AU  - Pascal Martin
AU  - Christoph Ruschil
AU  - Jutta Dünschede
AU  - Roswitha Kemmner
AU  - Natalie Rumpel
AU  - Benjamin Berger
AU  - Andreas Totzeck
AU  - Tim Hagenacker
AU  - Benjamin Stolte
AU  - Raffaele Iorio
AU  - Amelia Evoli
AU  - Silvia Falso
AU  - Carlo Antozzi
AU  - Rita Frangiamore
AU  - Fiammetta Vanoli
AU  - Elena Rinaldi
AU  - Kazushi Deguchi
AU  - Naoya Minami
AU  - Yuriko Nagane
AU  - Yasushi Suzuki
AU  - Sayaka Ishida
AU  - Shigeaki Suzuki
AU  - Jin Nakahara
AU  - Astushi Nagaoka
AU  - Shunsuke Yoshimura
AU  - Shingo Konno
AU  - Youko Tsuya
AU  - Akiyuki Uzawa
AU  - Tomoya Kubota
AU  - Masanori Takahashi
AU  - Tatsusada Okuno
AU  - Hiroyuki Murai
AU  - Nils Erik Gilhus
AU  - Marion Boldingh
AU  - Tone Hakvåg Rønning
AU  - Urszula Chyrchel-Paszkiewicz
AU  - Klaudiusz Kumor
AU  - Tomasz Zielinski
AU  - Krzysztof Banaszkiewicz
AU  - Michał Błaż
AU  - Agata Kłósek
AU  - Mariola Świderek-Matysiak
AU  - Andrzej Szczudlik
AU  - Aneta Paśko
AU  - Lech Szczechowski
AU  - Marta Banach
AU  - Jan Ilkowski
AU  - Solange Kapetanovic Garcia
AU  - Patricia Ortiz Bagan
AU  - Ana Belén Cánovas Segura
AU  - Joana Turon Sans
AU  - Nuria Vidal Fernandez
AU  - Elena Cortes Vicente
AU  - Patricia Rodrigo Armenteros
AU  - Mohammad Ashraghi
AU  - Ana Cavey
AU  - Liam Haslam
AU  - Anna Emery
AU  - Kore Liow
AU  - Sharon Yegiaian
AU  - Alexandru Barboi
AU  - Rosa Maria Vazquez
AU  - Joshua Lennon
AU  - Robert M Pascuzzi
AU  - Cynthia Bodkin
AU  - Sandra Guingrich
AU  - Adam Comer
AU  - Mark Bromberg
AU  - Teresa Janecki
AU  - Sami Saba
AU  - Marco Tellez
AU  - Bakri Elsheikh
AU  - Miriam Freimer
AU  - Sarah Heintzman
AU  - Raghav Govindarajan
AU  - Jeffrey Guptill
AU  - Janice M Massey
AU  - Vern Juel
AU  - Natalia Gonzalez
AU  - Ali A Habib
AU  - Tahseen Mozaffar
AU  - Manisha Korb
AU  - Namita Goyal
AU  - Hannah Machemehl
AU  - Georgios Manousakis
AU  - Jeffrey Allen
AU  - Emily Harper
AU  - Constantine Farmakidis
AU  - Lilli Saavedra
AU  - Mazen Dimachkie
AU  - Mamatha Pasnoor
AU  - Salma Akhter
AU  - Said Beydoun
AU  - Courtney McIlduff
AU  - Joan Nye
AU  - Bhaskar Roy
AU  - Bailey Munro Sheldon
AU  - Richard Nowak
AU  - Benjamin Barnes
AU  - Michael Rivner
AU  - Niraja Suresh
AU  - Jessica Shaw
AU  - Brittany Harvey
AU  - Lucy Lam
AU  - Nikki Thomas
AU  - Manisha Chopra
AU  - Rebecca E Traub
AU  - Sarah Jones
AU  - Mary Wagoner
AU  - Sejla Smajic
AU  - Radwa Aly
AU  - Jonathan Katz
AU  - Henry Chen
AU  - Robert G Miller
AU  - Liberty Jenkins
AU  - Shaida Khan
AU  - Bhupendra Khatri
AU  - Lisa Sershon
AU  - Pantelis Pavlakis
AU  - Shara Holzberg
AU  - Yuebing Li
AU  - Irys B Caristo
AU  - Robert Marquardt
AU  - Debbie Hastings
AU  - Jacob Rube
AU  - Robert P Lisak
AU  - Aparna Choudhury
AU  - Katherine Ruzhansky
AU  - Amit Sachdev
AU  - Susan Shin
AU  - Joan Bratton
AU  - Mary Fetter
AU  - Naya McKinnon
AU  - Jonathan McKinnon
AU  - Laura Sissons-Ross
AU  - Amos Sahu
AU  - B Jane Distad
PY  - 2023
JO  - The Lancet Neurology
DO  - 10.1016/s1474-4422(23)00080-7
UR  - https://doi.org/10.1016/s1474-4422(23)00080-7
ER  - 

APA

Howard, J. F., Bresch, S., Genge, A., Hewamadduma, C., Hinton, J., Hussain, Y., Juntas-Morales, R., Kaminski, H. J., Maniaol, A., Mantegazza, R., Masuda, M., Sivakumar, K., Śmiłowski, M., Utsugisawa, K., Vu, T., Weiss, M. D., Zajda, M., Boroojerdi, B., Brock, M., Borderie, G. D. L., Duda, P. W., Lowcock, R., Vanderkelen, M., Leite, M. I., Sembinelli, D., Teitelbaum, J., Nicolle, M., Bernard, E., Svahn, J., Spinazzi, M., Stojkovic, T., Demeret, S., Weiss, N., Guennec, L. L., Messai, S., Tranchant, C., Nadaj-Pakleza, A., Chanson, J., Suliman, M., Zaidi, L., Tard, C., Lecointe, P., Zschüntzsch, J., Schmidt, J., Glaubitz, S., Zeng, R., Scholl, M., Kowarik, M., Ziemann, U., Krumbholz, M., Martin, P., Ruschil, C., Dünschede, J., Kemmner, R., Rumpel, N., Berger, B., Totzeck, A., Hagenacker, T., Stolte, B., Iorio, R., Evoli, A., Falso, S., Antozzi, C., Frangiamore, R., Vanoli, F., Rinaldi, E., Deguchi, K., Minami, N., Nagane, Y., Suzuki, Y., Ishida, S., Suzuki, S., Nakahara, J., Nagaoka, A., Yoshimura, S., Konno, S., Tsuya, Y., Uzawa, A., Kubota, T., Takahashi, M., Okuno, T., Murai, H., Gilhus, N. E., Boldingh, M., Rønning, T. H., Chyrchel-Paszkiewicz, U., Kumor, K., Zielinski, T., Banaszkiewicz, K., Błaż, M., Kłósek, A., Świderek-Matysiak, M., Szczudlik, A., Paśko, A., Szczechowski, L., Banach, M., Ilkowski, J., Garcia, S. K., Bagan, P. O., Segura, A. B. C., Sans, J. T., Fernandez, N. V., Vicente, E. C., Armenteros, P. R., Ashraghi, M., Cavey, A., Haslam, L., Emery, A., Liow, K., Yegiaian, S., Barboi, A., Vazquez, R. M., Lennon, J., Pascuzzi, R. M., Bodkin, C., Guingrich, S., Comer, A., Bromberg, M., Janecki, T., Saba, S., Tellez, M., Elsheikh, B., Freimer, M., Heintzman, S., Govindarajan, R., Guptill, J., Massey, J. M., Juel, V., Gonzalez, N., Habib, A. A., Mozaffar, T., Korb, M., Goyal, N., Machemehl, H., Manousakis, G., Allen, J., Harper, E., Farmakidis, C., Saavedra, L., Dimachkie, M., Pasnoor, M., Akhter, S., Beydoun, S., McIlduff, C., Nye, J., Roy, B., Sheldon, B. M., Nowak, R., Barnes, B., Rivner, M., Suresh, N., Shaw, J., Harvey, B., Lam, L., Thomas, N., Chopra, M., Traub, R. E., Jones, S., Wagoner, M., Smajic, S., Aly, R., Katz, J., Chen, H., Miller, R. G., Jenkins, L., Khan, S., Khatri, B., Sershon, L., Pavlakis, P., Holzberg, S., Li, Y., Caristo, I. B., Marquardt, R., Hastings, D., Rube, J., Lisak, R. P., Choudhury, A., Ruzhansky, K., Sachdev, A., Shin, S., Bratton, J., Fetter, M., McKinnon, N., McKinnon, J., Sissons-Ross, L., Sahu, A., & Distad, B. J. (2023). Safety and efficacy of zilucoplan in patients with generalised myasthenia gravis (RAISE): a randomised, double-blind, placebo-controlled, phase 3 study. The Lancet Neurology. https://doi.org/10.1016/s1474-4422(23)00080-7