Safety and efficacy of individualised exercise and NAD<sup>+</sup> precursor supplementation in patients with Friedreich's ataxia in the USA: a single-centre, 2 × 2 factorial, randomised controlled trial.

Lin KY, Bucha A, McSweeney K, Wade KL, Karaj A, Tamaroff J, O'Malley S, Chung NM, Cilenti NA, Wanner J, Adzika GK, Mesaros C, Blair IA, Rojsajjakul T, Serai S, Farmer J, Bryant K, Lu Y, Harhay MO, Weber DR, Paridon SM, Seifert EL, Putt ME, Zamani P, Baur JA, Lynch DR, McCormack SE.

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DOI: 10.1016/s1474-4422(26)00082-7
Published: 2026-05-01
Container: Lancet Neurol
Publisher: Not recorded
Open access: no

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limited evidence Score 43/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

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Cite this work

BibTeX

@article{allodium:10.1016/s1474-4422-26-00082-7,
  title = {Safety and efficacy of individualised exercise and NAD\&lt;sup\&gt;+\&lt;/sup\&gt; precursor supplementation in patients with Friedreich's ataxia in the USA: a single-centre, 2 × 2 factorial, randomised controlled trial.},
  author = {Lin KY and  Bucha A and  McSweeney K and  Wade KL and  Karaj A and  Tamaroff J and  O'Malley S and  Chung NM and  Cilenti NA and  Wanner J and  Adzika GK and  Mesaros C and  Blair IA and  Rojsajjakul T and  Serai S and  Farmer J and  Bryant K and  Lu Y and  Harhay MO and  Weber DR and  Paridon SM and  Seifert EL and  Putt ME and  Zamani P and  Baur JA and  Lynch DR and  McCormack SE.},
  year = {2026},
  journal = {Lancet Neurol},
  doi = {10.1016/s1474-4422(26)00082-7},
  url = {https://doi.org/10.1016/s1474-4422(26)00082-7}
}

RIS

TY  - JOUR
TI  - Safety and efficacy of individualised exercise and NAD&lt;sup&gt;+&lt;/sup&gt; precursor supplementation in patients with Friedreich's ataxia in the USA: a single-centre, 2 × 2 factorial, randomised controlled trial.
AU  - Lin KY
AU  -  Bucha A
AU  -  McSweeney K
AU  -  Wade KL
AU  -  Karaj A
AU  -  Tamaroff J
AU  -  O'Malley S
AU  -  Chung NM
AU  -  Cilenti NA
AU  -  Wanner J
AU  -  Adzika GK
AU  -  Mesaros C
AU  -  Blair IA
AU  -  Rojsajjakul T
AU  -  Serai S
AU  -  Farmer J
AU  -  Bryant K
AU  -  Lu Y
AU  -  Harhay MO
AU  -  Weber DR
AU  -  Paridon SM
AU  -  Seifert EL
AU  -  Putt ME
AU  -  Zamani P
AU  -  Baur JA
AU  -  Lynch DR
AU  -  McCormack SE.
PY  - 2026
JO  - Lancet Neurol
DO  - 10.1016/s1474-4422(26)00082-7
UR  - https://doi.org/10.1016/s1474-4422(26)00082-7
ER  -

APA

KY, L., A, B., K, M., KL, W., A, K., J, T., S, O., NM, C., NA, C., J, W., GK, A., C, M., IA, B., T, R., S, S., J, F., K, B., Y, L., MO, H., DR, W., SM, P., EL, S., ME, P., P, Z., JA, B., DR, L., & SE., M. (2026). Safety and efficacy of individualised exercise and NAD<sup>+</sup> precursor supplementation in patients with Friedreich's ataxia in the USA: a single-centre, 2 × 2 factorial, randomised controlled trial.. Lancet Neurol. https://doi.org/10.1016/s1474-4422(26)00082-7

Source records

europe-pmc · retrieved 2026-09-26T02:00:52.135Z

Safety and efficacy of individualised exercise and NAD&lt;sup&gt;+&lt;/sup&gt; precursor supplementation in patients with Friedreich's ataxia in the USA: a single-centre, 2 × 2 factorial, randomised controlled trial.

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APA

Source records

Safety and efficacy of individualised exercise and NAD<sup>+</sup> precursor supplementation in patients with Friedreich's ataxia in the USA: a single-centre, 2 × 2 factorial, randomised controlled trial.