Parkinson's disease genetics across diverse ancestries: an observational genetic study of causal and risk variants with translational implications

BibTeX

@article{allodium:10.1016/s1474-4422-26-00198-5,
  title = {Parkinson's disease genetics across diverse ancestries: an observational genetic study of causal and risk variants with translational implications},
  author = {Lara M Lange and Zih-Hua Fang and Mary B Makarious and Nicole Kuznetsov and Kajsa Atterling Brolin and Shannon Ballard and Soraya Bardien and Maria Leila Doquenia and Peter Heutink and Henry Houlden and Hirotaka Iwaki and Simona Jasaityte and Lietsel Jones and Johanna Junker and Rauan Kaiyrzhanov and Mathew J Koretsky and Kishore R Kumar and Emilia Mabel Gatto and Claudia Perandones and Martin Radrizani and Gustavo DaPrat and Natalia Gonzalez Rojas and Melisa Espindola and Martin Cesarini and Maria Valentina Muller and Carlos Matias López Razquin and Bibiana Pizarro and Lucia Wang and Clarisa Marchetti and Cesar Avila and Griselda Alvarado and Luciana Rojas-Vazquez and Juan Pablo Diaz-Rearte and Marcelo Kauffman and Sergio Rodriguez and Dolores Gonzales and Pavel Alejandro Hernandez and Belen Ceballos and Florencia Echeverria and Gabriela Costa and Marcelo Merello and Federico Capparelli and Florencia Wainberg and Tomas Poklepovich and Florencia Mallou and Denise De Belder and Erick Gonzalez and Enrique Wagner and Robin Rodriguez and Alexander Quecana Janco and Bruno Lopes Santos-Lobato and Gracivane Lopes Eufraseo and Juliana Duarte and Marcella Montenegro and Tatiane Souza and Camille Sena and Ândrea Ribeiro-dos-Santos and Pedro Braga-Neto and Deborah Rangel and Marconny Cavalcante and Mateus Balsells and Vitor Tumas and Angela Vieira Pìmentel and Vanderci Borges and Carolina Candeias da Silva and Henrique Ballali Ferraz and Dayany Leonel Boone and Mariana Cavalcanti Costa and Egberto Reis Barbosa and Grace Letro and Artur F Schumacher-Schuh and Carlos R M Rieder and Gabriela Magalhães Pereira and Deise Cristine Friedrich and Thalya Osmilda Alves de Carvalho and Isabella Fonseca Benati and Jullivan Käfer Pasin and Vitor Picanço Lima Gomes and Marcelo Somma Tessari and Ingrid Lorena da Silva Gomes and Juan Sebastián Sánchez León and Paula Saffie-Awad and Gabriel Alves Marconi and Manoella Guatimuzim Testa da Silva and Gonzalo Arboleda and Oscar Bernal Pacheco and Tatiana Lopez Gonzalez and Humberto Arboleda and Carlos Eduardo Arboleda Bustos and Hebert Bernal Castro and Juan David Caicedo Narvaez and Kelly Bonilla Vargas and Jorge Orozco and Beatriz Munoz Ospina and Harold Londono and David Aguillon and Sonia Moreno and Omar Buritica and David Pineda and Marlene Jimenez Del Rio and Carlos Vélez Pardo and Sarita Firstman and Pedro Chana-Cuevas and Ximena Pizarro Correa and Consuelo Moos and Natalia Rojas and Patricio Olguin and Alicia Colombo and Juan Cristobal Nuñez and Andres De la Cerda and María Francisca Canals and Gonzalo Farías and Valentina Bessa and Mérida Terán and Pen Cheng Zhongxomg and Paula Saffie and Eduardo Perez and Dominga Berrios and Elías Fernandez and Marlene Valenzuela and Mario Fuentealba Sandoval and Susana Pineda and Floria Pancetti and Maria Eugenia Contreras Pinto and Benjamin Soto Flores and Gabriel Torrealba Acosta and Tanya Lobo-Prada and Jaime Fornaguera Trías and Álvaro Hernandez Guillen and Roger Rodríguez and Rossy Cruz Vicioso and Ernestina Castro and Alpher Perez and Sergio Mosquera and Cesarina Torres and Janfreisy Carbonell and Reyna M Durón and Alex Medina and Heike Hesse and Evelin Alvarez Herrera and Eduardo P Murillo and Glenda Oliva and Susana Pena and Tatiana Ascencio and Oscar Peña Rodas and Faryd Llerena Toro and Michael Castelo and Carlos Rodriguez and Mayela Rodríguez-Violante and Ana Jimena Hernández-Medrano and Amin Cervantes-Arriaga and Daniel Martinez Ramirez and Sarael Alcauter and Alejandra Medina Rivera and Alejandra E Ruiz-Contreras and Miguel E Rentería and Alejandra Lázaro Figueroa and Juan Manuel Esquivias-Farias and Andrés Morales de-Arcia and Alejandra Zayas Del Moral and Damaris Vazquez-Guevara and Yamil Matuk-Pérez and Carlos Manuel Guerra-Galicia and Ildefonso Rodriguez-Leyva and Karla Salinas-Barboza and Eugenia Morelos Figaredo and Omar Cardenas-Saenz and Nadia A Gandarilla-Martínez and Sara Isais Millán and Teresa Pérez-Torres and Domingo Martinez and Ingrid Estada Bellmann and Roberto Trejo-Ayala and Carlos Alberto Ponce-Fernández and Dane Oropeza and Mario Cornejo Olivas and Julia Rios Pinto and Angel Medina and Ivan Cornejo Herrera and Koni Mejia-Rojas and Cintia Armas Puente and Edward Ochoa Valle and Marcela Alvarado Morales and Elison Sarapura Castro and Andrea Rivera-Valdivia and Maryenela Illanes Manrique and Carla Manrique Enciso and Victoria Marca Ysabel and Olimpio Ortega Dávila and Freddy Requejo-Navarro and Alid Manrique Palomino and Gabriela Gushiken Oshiro and Laura Zelada Rios and Elena Dieguez and Victor Raggio and Andres Lescano and Angel Vinuela and Esther Colon and Thiago P Leal and Emily Waldo and Felipe Duarte Zambrano and Miguel Inca-Martinez and Janvi Ramchandra and Kamilah Stark and Henry Mauricio Chaparro-Solano and Daniel Teixeira-dos-Santos and Emily Leininger and Nicolas Gutierrez and Valerie Rico and Paula Reyes Pérez and Ignacio F Mata and Karen Nuytemans and Anisley Martinez and Liena Infante and Hampton L Leonard and Kristin S Levine and Shen-Yang Lim and Niccoló E Mencacci and Wael M Y Mohamed and Mike A Nalls and Alastair J Noyce and Rajeev Ojha and Njideka U Okubadejo and Shoaib ur Rehman and Laurel Screven and Chingiz Shashkin and Sophia Sopromadze and Eleanor J Stafford and Ai Huey Tan and Manuela Tan and Zaruhi Tavadyan and Joanne Trinh and Bayasgalan Tserensodnom and Enza Maria Valente and Dan Vitale and Nazira Zharkinbekova and Katja Lohmann and Sara Bandres-Ciga and Cornelis Blauwendraat and Andrew B Singleton and Huw R Morris and Christine Klein},
  year = {2026},
  journal = {The Lancet Neurology},
  doi = {10.1016/s1474-4422(26)00198-5},
  url = {https://doi.org/10.1016/s1474-4422(26)00198-5}
}

RIS

TY  - JOUR
TI  - Parkinson's disease genetics across diverse ancestries: an observational genetic study of causal and risk variants with translational implications
AU  - Lara M Lange
AU  - Zih-Hua Fang
AU  - Mary B Makarious
AU  - Nicole Kuznetsov
AU  - Kajsa Atterling Brolin
AU  - Shannon Ballard
AU  - Soraya Bardien
AU  - Maria Leila Doquenia
AU  - Peter Heutink
AU  - Henry Houlden
AU  - Hirotaka Iwaki
AU  - Simona Jasaityte
AU  - Lietsel Jones
AU  - Johanna Junker
AU  - Rauan Kaiyrzhanov
AU  - Mathew J Koretsky
AU  - Kishore R Kumar
AU  - Emilia Mabel Gatto
AU  - Claudia Perandones
AU  - Martin Radrizani
AU  - Gustavo DaPrat
AU  - Natalia Gonzalez Rojas
AU  - Melisa Espindola
AU  - Martin Cesarini
AU  - Maria Valentina Muller
AU  - Carlos Matias López Razquin
AU  - Bibiana Pizarro
AU  - Lucia Wang
AU  - Clarisa Marchetti
AU  - Cesar Avila
AU  - Griselda Alvarado
AU  - Luciana Rojas-Vazquez
AU  - Juan Pablo Diaz-Rearte
AU  - Marcelo Kauffman
AU  - Sergio Rodriguez
AU  - Dolores Gonzales
AU  - Pavel Alejandro Hernandez
AU  - Belen Ceballos
AU  - Florencia Echeverria
AU  - Gabriela Costa
AU  - Marcelo Merello
AU  - Federico Capparelli
AU  - Florencia Wainberg
AU  - Tomas Poklepovich
AU  - Florencia Mallou
AU  - Denise De Belder
AU  - Erick Gonzalez
AU  - Enrique Wagner
AU  - Robin Rodriguez
AU  - Alexander Quecana Janco
AU  - Bruno Lopes Santos-Lobato
AU  - Gracivane Lopes Eufraseo
AU  - Juliana Duarte
AU  - Marcella Montenegro
AU  - Tatiane Souza
AU  - Camille Sena
AU  - Ândrea Ribeiro-dos-Santos
AU  - Pedro Braga-Neto
AU  - Deborah Rangel
AU  - Marconny Cavalcante
AU  - Mateus Balsells
AU  - Vitor Tumas
AU  - Angela Vieira Pìmentel
AU  - Vanderci Borges
AU  - Carolina Candeias da Silva
AU  - Henrique Ballali Ferraz
AU  - Dayany Leonel Boone
AU  - Mariana Cavalcanti Costa
AU  - Egberto Reis Barbosa
AU  - Grace Letro
AU  - Artur F Schumacher-Schuh
AU  - Carlos R M Rieder
AU  - Gabriela Magalhães Pereira
AU  - Deise Cristine Friedrich
AU  - Thalya Osmilda Alves de Carvalho
AU  - Isabella Fonseca Benati
AU  - Jullivan Käfer Pasin
AU  - Vitor Picanço Lima Gomes
AU  - Marcelo Somma Tessari
AU  - Ingrid Lorena da Silva Gomes
AU  - Juan Sebastián Sánchez León
AU  - Paula Saffie-Awad
AU  - Gabriel Alves Marconi
AU  - Manoella Guatimuzim Testa da Silva
AU  - Gonzalo Arboleda
AU  - Oscar Bernal Pacheco
AU  - Tatiana Lopez Gonzalez
AU  - Humberto Arboleda
AU  - Carlos Eduardo Arboleda Bustos
AU  - Hebert Bernal Castro
AU  - Juan David Caicedo Narvaez
AU  - Kelly Bonilla Vargas
AU  - Jorge Orozco
AU  - Beatriz Munoz Ospina
AU  - Harold Londono
AU  - David Aguillon
AU  - Sonia Moreno
AU  - Omar Buritica
AU  - David Pineda
AU  - Marlene Jimenez Del Rio
AU  - Carlos Vélez Pardo
AU  - Sarita Firstman
AU  - Pedro Chana-Cuevas
AU  - Ximena Pizarro Correa
AU  - Consuelo Moos
AU  - Natalia Rojas
AU  - Patricio Olguin
AU  - Alicia Colombo
AU  - Juan Cristobal Nuñez
AU  - Andres De la Cerda
AU  - María Francisca Canals
AU  - Gonzalo Farías
AU  - Valentina Bessa
AU  - Mérida Terán
AU  - Pen Cheng Zhongxomg
AU  - Paula Saffie
AU  - Eduardo Perez
AU  - Dominga Berrios
AU  - Elías Fernandez
AU  - Marlene Valenzuela
AU  - Mario Fuentealba Sandoval
AU  - Susana Pineda
AU  - Floria Pancetti
AU  - Maria Eugenia Contreras Pinto
AU  - Benjamin Soto Flores
AU  - Gabriel Torrealba Acosta
AU  - Tanya Lobo-Prada
AU  - Jaime Fornaguera Trías
AU  - Álvaro Hernandez Guillen
AU  - Roger Rodríguez
AU  - Rossy Cruz Vicioso
AU  - Ernestina Castro
AU  - Alpher Perez
AU  - Sergio Mosquera
AU  - Cesarina Torres
AU  - Janfreisy Carbonell
AU  - Reyna M Durón
AU  - Alex Medina
AU  - Heike Hesse
AU  - Evelin Alvarez Herrera
AU  - Eduardo P Murillo
AU  - Glenda Oliva
AU  - Susana Pena
AU  - Tatiana Ascencio
AU  - Oscar Peña Rodas
AU  - Faryd Llerena Toro
AU  - Michael Castelo
AU  - Carlos Rodriguez
AU  - Mayela Rodríguez-Violante
AU  - Ana Jimena Hernández-Medrano
AU  - Amin Cervantes-Arriaga
AU  - Daniel Martinez Ramirez
AU  - Sarael Alcauter
AU  - Alejandra Medina Rivera
AU  - Alejandra E Ruiz-Contreras
AU  - Miguel E Rentería
AU  - Alejandra Lázaro Figueroa
AU  - Juan Manuel Esquivias-Farias
AU  - Andrés Morales de-Arcia
AU  - Alejandra Zayas Del Moral
AU  - Damaris Vazquez-Guevara
AU  - Yamil Matuk-Pérez
AU  - Carlos Manuel Guerra-Galicia
AU  - Ildefonso Rodriguez-Leyva
AU  - Karla Salinas-Barboza
AU  - Eugenia Morelos Figaredo
AU  - Omar Cardenas-Saenz
AU  - Nadia A Gandarilla-Martínez
AU  - Sara Isais Millán
AU  - Teresa Pérez-Torres
AU  - Domingo Martinez
AU  - Ingrid Estada Bellmann
AU  - Roberto Trejo-Ayala
AU  - Carlos Alberto Ponce-Fernández
AU  - Dane Oropeza
AU  - Mario Cornejo Olivas
AU  - Julia Rios Pinto
AU  - Angel Medina
AU  - Ivan Cornejo Herrera
AU  - Koni Mejia-Rojas
AU  - Cintia Armas Puente
AU  - Edward Ochoa Valle
AU  - Marcela Alvarado Morales
AU  - Elison Sarapura Castro
AU  - Andrea Rivera-Valdivia
AU  - Maryenela Illanes Manrique
AU  - Carla Manrique Enciso
AU  - Victoria Marca Ysabel
AU  - Olimpio Ortega Dávila
AU  - Freddy Requejo-Navarro
AU  - Alid Manrique Palomino
AU  - Gabriela Gushiken Oshiro
AU  - Laura Zelada Rios
AU  - Elena Dieguez
AU  - Victor Raggio
AU  - Andres Lescano
AU  - Angel Vinuela
AU  - Esther Colon
AU  - Thiago P Leal
AU  - Emily Waldo
AU  - Felipe Duarte Zambrano
AU  - Miguel Inca-Martinez
AU  - Janvi Ramchandra
AU  - Kamilah Stark
AU  - Henry Mauricio Chaparro-Solano
AU  - Daniel Teixeira-dos-Santos
AU  - Emily Leininger
AU  - Nicolas Gutierrez
AU  - Valerie Rico
AU  - Paula Reyes Pérez
AU  - Ignacio F Mata
AU  - Karen Nuytemans
AU  - Anisley Martinez
AU  - Liena Infante
AU  - Hampton L Leonard
AU  - Kristin S Levine
AU  - Shen-Yang Lim
AU  - Niccoló E Mencacci
AU  - Wael M Y Mohamed
AU  - Mike A Nalls
AU  - Alastair J Noyce
AU  - Rajeev Ojha
AU  - Njideka U Okubadejo
AU  - Shoaib ur Rehman
AU  - Laurel Screven
AU  - Chingiz Shashkin
AU  - Sophia Sopromadze
AU  - Eleanor J Stafford
AU  - Ai Huey Tan
AU  - Manuela Tan
AU  - Zaruhi Tavadyan
AU  - Joanne Trinh
AU  - Bayasgalan Tserensodnom
AU  - Enza Maria Valente
AU  - Dan Vitale
AU  - Nazira Zharkinbekova
AU  - Katja Lohmann
AU  - Sara Bandres-Ciga
AU  - Cornelis Blauwendraat
AU  - Andrew B Singleton
AU  - Huw R Morris
AU  - Christine Klein
PY  - 2026
JO  - The Lancet Neurology
DO  - 10.1016/s1474-4422(26)00198-5
UR  - https://doi.org/10.1016/s1474-4422(26)00198-5
ER  - 

APA

Lange, L. M., Fang, Z., Makarious, M. B., Kuznetsov, N., Brolin, K. A., Ballard, S., Bardien, S., Doquenia, M. L., Heutink, P., Houlden, H., Iwaki, H., Jasaityte, S., Jones, L., Junker, J., Kaiyrzhanov, R., Koretsky, M. J., Kumar, K. R., Gatto, E. M., Perandones, C., Radrizani, M., DaPrat, G., Rojas, N. G., Espindola, M., Cesarini, M., Muller, M. V., Razquin, C. M. L., Pizarro, B., Wang, L., Marchetti, C., Avila, C., Alvarado, G., Rojas-Vazquez, L., Diaz-Rearte, J. P., Kauffman, M., Rodriguez, S., Gonzales, D., Hernandez, P. A., Ceballos, B., Echeverria, F., Costa, G., Merello, M., Capparelli, F., Wainberg, F., Poklepovich, T., Mallou, F., Belder, D. D., Gonzalez, E., Wagner, E., Rodriguez, R., Janco, A. Q., Santos-Lobato, B. L., Eufraseo, G. L., Duarte, J., Montenegro, M., Souza, T., Sena, C., Ribeiro-dos-Santos, Â., Braga-Neto, P., Rangel, D., Cavalcante, M., Balsells, M., Tumas, V., Pìmentel, A. V., Borges, V., Silva, C. C. D., Ferraz, H. B., Boone, D. L., Costa, M. C., Barbosa, E. R., Letro, G., Schumacher-Schuh, A. F., Rieder, C. R. M., Pereira, G. M., Friedrich, D. C., Carvalho, T. O. A. D., Benati, I. F., Pasin, J. K., Gomes, V. P. L., Tessari, M. S., Gomes, I. L. D. S., León, J. S. S., Saffie-Awad, P., Marconi, G. A., Silva, M. G. T. D., Arboleda, G., Pacheco, O. B., Gonzalez, T. L., Arboleda, H., Bustos, C. E. A., Castro, H. B., Narvaez, J. D. C., Vargas, K. B., Orozco, J., Ospina, B. M., Londono, H., Aguillon, D., Moreno, S., Buritica, O., Pineda, D., Rio, M. J. D., Pardo, C. V., Firstman, S., Chana-Cuevas, P., Correa, X. P., Moos, C., Rojas, N., Olguin, P., Colombo, A., Nuñez, J. C., Cerda, A. D. L., Canals, M. F., Farías, G., Bessa, V., Terán, M., Zhongxomg, P. C., Saffie, P., Perez, E., Berrios, D., Fernandez, E., Valenzuela, M., Sandoval, M. F., Pineda, S., Pancetti, F., Pinto, M. E. C., Flores, B. S., Acosta, G. T., Lobo-Prada, T., Trías, J. F., Guillen, Á. H., Rodríguez, R., Vicioso, R. C., Castro, E., Perez, A., Mosquera, S., Torres, C., Carbonell, J., Durón, R. M., Medina, A., Hesse, H., Herrera, E. A., Murillo, E. P., Oliva, G., Pena, S., Ascencio, T., Rodas, O. P., Toro, F. L., Castelo, M., Rodriguez, C., Rodríguez-Violante, M., Hernández-Medrano, A. J., Cervantes-Arriaga, A., Ramirez, D. M., Alcauter, S., Rivera, A. M., Ruiz-Contreras, A. E., Rentería, M. E., Figueroa, A. L., Esquivias-Farias, J. M., de-Arcia, A. M., Moral, A. Z. D., Vazquez-Guevara, D., Matuk-Pérez, Y., Guerra-Galicia, C. M., Rodriguez-Leyva, I., Salinas-Barboza, K., Figaredo, E. M., Cardenas-Saenz, O., Gandarilla-Martínez, N. A., Millán, S. I., Pérez-Torres, T., Martinez, D., Bellmann, I. E., Trejo-Ayala, R., Ponce-Fernández, C. A., Oropeza, D., Olivas, M. C., Pinto, J. R., Medina, A., Herrera, I. C., Mejia-Rojas, K., Puente, C. A., Valle, E. O., Morales, M. A., Castro, E. S., Rivera-Valdivia, A., Manrique, M. I., Enciso, C. M., Ysabel, V. M., Dávila, O. O., Requejo-Navarro, F., Palomino, A. M., Oshiro, G. G., Rios, L. Z., Dieguez, E., Raggio, V., Lescano, A., Vinuela, A., Colon, E., Leal, T. P., Waldo, E., Zambrano, F. D., Inca-Martinez, M., Ramchandra, J., Stark, K., Chaparro-Solano, H. M., Teixeira-dos-Santos, D., Leininger, E., Gutierrez, N., Rico, V., Pérez, P. R., Mata, I. F., Nuytemans, K., Martinez, A., Infante, L., Leonard, H. L., Levine, K. S., Lim, S., Mencacci, N. E., Mohamed, W. M. Y., Nalls, M. A., Noyce, A. J., Ojha, R., Okubadejo, N. U., Rehman, S. U., Screven, L., Shashkin, C., Sopromadze, S., Stafford, E. J., Tan, A. H., Tan, M., Tavadyan, Z., Trinh, J., Tserensodnom, B., Valente, E. M., Vitale, D., Zharkinbekova, N., Lohmann, K., Bandres-Ciga, S., Blauwendraat, C., Singleton, A. B., Morris, H. R., & Klein, C. (2026). Parkinson's disease genetics across diverse ancestries: an observational genetic study of causal and risk variants with translational implications. The Lancet Neurology. https://doi.org/10.1016/s1474-4422(26)00198-5