Efficacy and safety of tezepelumab versus placebo in adults with moderate to very severe chronic obstructive pulmonary disease (COURSE): a randomised, placebo-controlled, phase 2a trial
- DOI
- 10.1016/s2213-2600(24)00324-2
- Published
- 2025-01
- Container
- The Lancet Respiratory Medicine
- Publisher
- Elsevier BV
- Open access
- unknown
Credibility signals
uncertain Score 64/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.
Show all credibility signals
- supportingDOI registered: A matching record was returned by Crossref.
- supportingDOI resolves: A matching record was returned by Crossref.
- not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility.
- not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made.
- not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made.
- not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made.
- not scoredROR affiliation: Not checked or no result supplied; no credibility inference made.
- not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete.
- not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete.
- not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete.
- not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete.
- not scoredOpen access status: Not checked or no result supplied; no credibility inference made.
- not scoredPublication license: Not checked or no result supplied; no credibility inference made.
- not scoredPublication version: A publication version was supplied but is not scored.
- supportingMetadata completeness: All 6 scored descriptive metadata groups are present.
Cite this work
BibTeX
@article{allodium:10.1016/s2213-2600-24-00324-2,
title = {Efficacy and safety of tezepelumab versus placebo in adults with moderate to very severe chronic obstructive pulmonary disease (COURSE): a randomised, placebo-controlled, phase 2a trial},
author = {Dave Singh and Christopher E Brightling and Klaus F Rabe and MeiLan K Han and Stephanie A Christenson and M Bradley Drummond and Alberto Papi and Ian D Pavord and Nestor A Molfino and Gun Almqvist and Ales Kotalik and Åsa Hellqvist and Monika Gołąbek and Navreet S Sindhwani and Sandhia S Ponnarambil and Jasmin Belle-Isle and Jerome Nadeau and William Killorn and Bruno Francoeur and Emilie Millaire and Bonavuth Pek and Murdo Ferguson and Francois Maltais and Kieran Killian and Giuseppe Mazza and Lyle Melenka and Brandie Walker and Celine Bergeron and John FitzGerald and Ulla Møller Weinreich and Elisabeth Bendstrup and Celeste Porsbjerg and Charlotte Ulrik and Ingrid Titlestad and Christian Meyer and Ole Hilberg and Francis Couturaud and Claire Andrejak and Arnaud Bourdin and Gilles Devouassoux and Jean-Louis Pepin and Pascal Chanez and Arnaud Cavailles and Andreas Eich and Andrea Ludwig-Sengpiel and Henrik Watz and Thomas Schultz and Amir Bar-Shai and Ori Wand and Yochai Adir and Neville Berkman and Gershon Fink and David Shitrit and Gabriel Izbicki and Yael Raviv and Pascal Wielders and Martijn Goosens and Roxane Heller-Baan and Johannes in't Veen and Frank Custers and Yeon-Mok Oh and YongChul Lee and Jaeyeol Kim and Kwang-Ha Yoo and Jung-Won Park and Sang Haak Lee and Joong Hyun Ahn and Sook Young Lee and Jin Woo Kim and Kwan Ho Lee and Luis Mateos Caballero and Elsa Naval Sendra and David Ramos Barbón and José Luis Velasco Garrido and Bernardino Alcázar Navarrete and Dinesh Saralaya and Michael Crooks and Pallav Shah and Rekha Chaudhuri and Anthony de Soyza and Monica Nordstrom and Akshay Dwarakanath and Steven Weinstein and David Pham and John Mitchell and Selwyn Spangenthal and Sever Surdulescu and Michael Denenberg and Sady Alpizar and David Maybee and Timothy Moriarty and Faisal Fakih and Richard Beasley and Marvin Heuer and Amit Patel and Jeffrey Dorf and Rafael Martinez and Shahrukh Kureishy and Ryan Klein and Mitzie Hewitt and Jeremy Cole and Emory Robinette and Edward Cordasco and Robert Garver and Gerard Criner and Frank Sciurba and Edward Kerwin and Gregg Lucksinger and John Delgado and David Russian and Geoffrey Chupp},
year = {2025},
journal = {The Lancet Respiratory Medicine},
doi = {10.1016/s2213-2600(24)00324-2},
url = {https://doi.org/10.1016/s2213-2600(24)00324-2}
}RIS
TY - JOUR TI - Efficacy and safety of tezepelumab versus placebo in adults with moderate to very severe chronic obstructive pulmonary disease (COURSE): a randomised, placebo-controlled, phase 2a trial AU - Dave Singh AU - Christopher E Brightling AU - Klaus F Rabe AU - MeiLan K Han AU - Stephanie A Christenson AU - M Bradley Drummond AU - Alberto Papi AU - Ian D Pavord AU - Nestor A Molfino AU - Gun Almqvist AU - Ales Kotalik AU - Åsa Hellqvist AU - Monika Gołąbek AU - Navreet S Sindhwani AU - Sandhia S Ponnarambil AU - Jasmin Belle-Isle AU - Jerome Nadeau AU - William Killorn AU - Bruno Francoeur AU - Emilie Millaire AU - Bonavuth Pek AU - Murdo Ferguson AU - Francois Maltais AU - Kieran Killian AU - Giuseppe Mazza AU - Lyle Melenka AU - Brandie Walker AU - Celine Bergeron AU - John FitzGerald AU - Ulla Møller Weinreich AU - Elisabeth Bendstrup AU - Celeste Porsbjerg AU - Charlotte Ulrik AU - Ingrid Titlestad AU - Christian Meyer AU - Ole Hilberg AU - Francis Couturaud AU - Claire Andrejak AU - Arnaud Bourdin AU - Gilles Devouassoux AU - Jean-Louis Pepin AU - Pascal Chanez AU - Arnaud Cavailles AU - Andreas Eich AU - Andrea Ludwig-Sengpiel AU - Henrik Watz AU - Thomas Schultz AU - Amir Bar-Shai AU - Ori Wand AU - Yochai Adir AU - Neville Berkman AU - Gershon Fink AU - David Shitrit AU - Gabriel Izbicki AU - Yael Raviv AU - Pascal Wielders AU - Martijn Goosens AU - Roxane Heller-Baan AU - Johannes in't Veen AU - Frank Custers AU - Yeon-Mok Oh AU - YongChul Lee AU - Jaeyeol Kim AU - Kwang-Ha Yoo AU - Jung-Won Park AU - Sang Haak Lee AU - Joong Hyun Ahn AU - Sook Young Lee AU - Jin Woo Kim AU - Kwan Ho Lee AU - Luis Mateos Caballero AU - Elsa Naval Sendra AU - David Ramos Barbón AU - José Luis Velasco Garrido AU - Bernardino Alcázar Navarrete AU - Dinesh Saralaya AU - Michael Crooks AU - Pallav Shah AU - Rekha Chaudhuri AU - Anthony de Soyza AU - Monica Nordstrom AU - Akshay Dwarakanath AU - Steven Weinstein AU - David Pham AU - John Mitchell AU - Selwyn Spangenthal AU - Sever Surdulescu AU - Michael Denenberg AU - Sady Alpizar AU - David Maybee AU - Timothy Moriarty AU - Faisal Fakih AU - Richard Beasley AU - Marvin Heuer AU - Amit Patel AU - Jeffrey Dorf AU - Rafael Martinez AU - Shahrukh Kureishy AU - Ryan Klein AU - Mitzie Hewitt AU - Jeremy Cole AU - Emory Robinette AU - Edward Cordasco AU - Robert Garver AU - Gerard Criner AU - Frank Sciurba AU - Edward Kerwin AU - Gregg Lucksinger AU - John Delgado AU - David Russian AU - Geoffrey Chupp PY - 2025 JO - The Lancet Respiratory Medicine DO - 10.1016/s2213-2600(24)00324-2 UR - https://doi.org/10.1016/s2213-2600(24)00324-2 ER -
APA
Singh, D., Brightling, C. E., Rabe, K. F., Han, M. K., Christenson, S. A., Drummond, M. B., Papi, A., Pavord, I. D., Molfino, N. A., Almqvist, G., Kotalik, A., Hellqvist, Å., Gołąbek, M., Sindhwani, N. S., Ponnarambil, S. S., Belle-Isle, J., Nadeau, J., Killorn, W., Francoeur, B., Millaire, E., Pek, B., Ferguson, M., Maltais, F., Killian, K., Mazza, G., Melenka, L., Walker, B., Bergeron, C., FitzGerald, J., Weinreich, U. M., Bendstrup, E., Porsbjerg, C., Ulrik, C., Titlestad, I., Meyer, C., Hilberg, O., Couturaud, F., Andrejak, C., Bourdin, A., Devouassoux, G., Pepin, J., Chanez, P., Cavailles, A., Eich, A., Ludwig-Sengpiel, A., Watz, H., Schultz, T., Bar-Shai, A., Wand, O., Adir, Y., Berkman, N., Fink, G., Shitrit, D., Izbicki, G., Raviv, Y., Wielders, P., Goosens, M., Heller-Baan, R., Veen, J. I., Custers, F., Oh, Y., Lee, Y., Kim, J., Yoo, K., Park, J., Lee, S. H., Ahn, J. H., Lee, S. Y., Kim, J. W., Lee, K. H., Caballero, L. M., Sendra, E. N., Barbón, D. R., Garrido, J. L. V., Navarrete, B. A., Saralaya, D., Crooks, M., Shah, P., Chaudhuri, R., Soyza, A. D., Nordstrom, M., Dwarakanath, A., Weinstein, S., Pham, D., Mitchell, J., Spangenthal, S., Surdulescu, S., Denenberg, M., Alpizar, S., Maybee, D., Moriarty, T., Fakih, F., Beasley, R., Heuer, M., Patel, A., Dorf, J., Martinez, R., Kureishy, S., Klein, R., Hewitt, M., Cole, J., Robinette, E., Cordasco, E., Garver, R., Criner, G., Sciurba, F., Kerwin, E., Lucksinger, G., Delgado, J., Russian, D., & Chupp, G. (2025). Efficacy and safety of tezepelumab versus placebo in adults with moderate to very severe chronic obstructive pulmonary disease (COURSE): a randomised, placebo-controlled, phase 2a trial. The Lancet Respiratory Medicine. https://doi.org/10.1016/s2213-2600(24)00324-2
Source records
- crossref · retrieved 2026-09-26T21:53:02.213Z