Bedside identification of subphenotypes in acute respiratory failure (PHIND): a multicentre, observational cohort study

Kiran Reddy, Pratik Sinha, David B Antcliffe, Clíona McDowell, Pauline A Bradley, Laura Black, Lynn Murphy, Judit Barbaras, John Conlon, Luigi Camporota, Marlies Ostermann, Phillip Hopkins, Tamas Szakmany, Shiney Cherian, Ingeborg Welters, David Brealey, Dhruv Parekh, Anthony J Rostron, Lieuwe D J Bos, Alistair Nichol, Manu Shankar-Hari, Anthony C Gordon, Kevin Delucchi, Cecilia M O'Kane, Michael A Matthay, Carolyn S Calfee, Daniel F McAuley, Barry Williams, Duncan Young, Maurice O'Kane, Christine McNally, Joanne Thompson, Judith McRory, Kevin Devlin, Lesley-Anne Dougan, Nuala Hannaway, Patricia Rafferty, Rejina Verghis, Roisin Thompson, Sean Reid, Peter Fitzgerald, Alisha Bothwell, Aoife McGreevy, Caolan Vaughan, Cecilia Fortugno, Huw Stacey, Jeremy Parker, John Lamont, Lauren Slater, Phil Robinson, Scott McKeown, Sophie McColgan, Ger Curley, Michelle Smyth, Sasha Keil, Gavin Perkins, Celinamma Maliaykal, Eleanor Reeves, Helen Taylor, Joanne Gresty, Lesley Horton, Teresa Melody, Will Leach, Nikitas Nikitas, Bethan Stowe, Elaine Freeman, Harry Lang, Helen McMillan, Kayleigh Spencer, Lauren Kimpton, Liana Stapleton, Michael Gillies, Matthew Faulds, Kathryn Puxty, Andrew Hurst, Callum Taylor, Dominic Rimmer, Beatriz Amaro de Jesus, Benjie Cendreda, Carolin Engelhard, Eirini Kosifidou, Eleanor Hendrie, Fabiola D'Amato, Gill Arbane, Kyma Morera, Sarah Fordyce, Shelley Lorah, Tahmina Matin, Caiomhe O'Dwyer, Maie Templeton, Roceld Rojo, Sonia Sousa Arias, Ziortza Fernandez de Pinedo Artaraz, Jeremy Henning, Burt Vergara, Clare Finney, Kevin O'Reilly, John Smith, Jonathan Bannard-Smith, Charlotte Taylor, Deborah Paripoorani, Katharine Wylie, Rachael Quayle, Richard Clark, Richard Innes, Amanda Groves, Ashly Thomas, Marc Chikhani, Alexandra Gibbins, Alice Baddeley, Alistair Morris, Anju Thomas, Catherine Walton, Cecilia Peters, David Ford, Julia Sampson, Stuart McKechnie, Grace Polley, Jean Wilson, Neil Davidson, Sally Beer, Brendan Sloan, Abigail Crew, Alexandra Metcalfe, Amy Major, Sarah Buckley, Dave Pogson, Andrew Walden, Haroon Waqar Uddin, Aayesha Kazi, Jillian Fitchett, Nicholas Truman, Michael Spivey, Carol Richards, Charlotte Barker Kirby, Eve Fletcher, Karen Burt, Kate Ralph, Rachel Chapman, Sarah Bean, Thomas Clark, Alexandra Carins, Arra Mahiya, David Shaw, Karen Williams, Maria Lopez Martinez, Maria Norris, Syamlan Ali, Victoria Waugh, Zachary Thomas, Aisling O'Neill, Chris Wright, Christine Turley, Erin Collins, Jackie Green, Kathryn Ward, Peter Pereira, Rebecca Cusack, Anne Harrison, Aidan Lingwood, Alice Baker, Belinda Roberts, Eloise Summerton, Jonathan Biss, Karen Salmon, Elankumaran Paramasivam, Liz Wilby, Susan Trott, Zoe Friar, Biji Thomas, Kathy Brickell, Lorna Murphy, Niamh Mahon, Lindsey Woods, Sarah Cornell, Alex Zapata, Anna Rowena Reyes, Deborah Smyth, Georgia Bercades, Gladys Martir, Ingrid Hass, Laura Gallagher, Caroline Dooley, Hazel Smith, Lisa Moody, Matt Wise, Alice Swindell, Carl Hawkins, Geraldine Ward, John Laffey, Lauren Ferguson, Martina Carey, Ritu Negi, Dominic Strachan, Kirsten Moar, Suzanne Clements, Valerie Page, Elvira Hoxha, Xiao Bei Zhao, Andrew Bentley

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DOI: 10.1016/s2213-2600(26)00040-8
Published: 2026-07
Container: The Lancet Respiratory Medicine
Publisher: Elsevier BV
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1016/s2213-2600-26-00040-8,
  title = {Bedside identification of subphenotypes in acute respiratory failure (PHIND): a multicentre, observational cohort study},
  author = {Kiran Reddy and Pratik Sinha and David B Antcliffe and Clíona McDowell and Pauline A Bradley and Laura Black and Lynn Murphy and Judit Barbaras and John Conlon and Luigi Camporota and Marlies Ostermann and Phillip Hopkins and Tamas Szakmany and Shiney Cherian and Ingeborg Welters and David Brealey and Dhruv Parekh and Anthony J Rostron and Lieuwe D J Bos and Alistair Nichol and Manu Shankar-Hari and Anthony C Gordon and Kevin Delucchi and Cecilia M O'Kane and Michael A Matthay and Carolyn S Calfee and Daniel F McAuley and Barry Williams and Duncan Young and Maurice O'Kane and Christine McNally and Joanne Thompson and Judith McRory and Kevin Devlin and Lesley-Anne Dougan and Nuala Hannaway and Patricia Rafferty and Rejina Verghis and Roisin Thompson and Sean Reid and Peter Fitzgerald and Alisha Bothwell and Aoife McGreevy and Caolan Vaughan and Cecilia Fortugno and Huw Stacey and Jeremy Parker and John Lamont and Lauren Slater and Phil Robinson and Scott McKeown and Sophie McColgan and Ger Curley and Michelle Smyth and Sasha Keil and Gavin Perkins and Celinamma Maliaykal and Eleanor Reeves and Helen Taylor and Joanne Gresty and Lesley Horton and Teresa Melody and Will Leach and Nikitas Nikitas and Bethan Stowe and Elaine Freeman and Harry Lang and Helen McMillan and Kayleigh Spencer and Lauren Kimpton and Liana Stapleton and Michael Gillies and Matthew Faulds and Kathryn Puxty and Andrew Hurst and Callum Taylor and Dominic Rimmer and Beatriz Amaro de Jesus and Benjie Cendreda and Carolin Engelhard and Eirini Kosifidou and Eleanor Hendrie and Fabiola D'Amato and Gill Arbane and Kyma Morera and Sarah Fordyce and Shelley Lorah and Tahmina Matin and Caiomhe O'Dwyer and Maie Templeton and Roceld Rojo and Sonia Sousa Arias and Ziortza Fernandez de Pinedo Artaraz and Jeremy Henning and Burt Vergara and Clare Finney and Kevin O'Reilly and John Smith and Jonathan Bannard-Smith and Charlotte Taylor and Deborah Paripoorani and Katharine Wylie and Rachael Quayle and Richard Clark and Richard Innes and Amanda Groves and Ashly Thomas and Marc Chikhani and Alexandra Gibbins and Alice Baddeley and Alistair Morris and Anju Thomas and Catherine Walton and Cecilia Peters and David Ford and Julia Sampson and Stuart McKechnie and Grace Polley and Jean Wilson and Neil Davidson and Sally Beer and Brendan Sloan and Abigail Crew and Alexandra Metcalfe and Amy Major and Sarah Buckley and Dave Pogson and Andrew Walden and Haroon Waqar Uddin and Aayesha Kazi and Jillian Fitchett and Nicholas Truman and Michael Spivey and Carol Richards and Charlotte Barker Kirby and Eve Fletcher and Karen Burt and Kate Ralph and Rachel Chapman and Sarah Bean and Thomas Clark and Alexandra Carins and Arra Mahiya and David Shaw and Karen Williams and Maria Lopez Martinez and Maria Norris and Syamlan Ali and Victoria Waugh and Zachary Thomas and Aisling O'Neill and Chris Wright and Christine Turley and Erin Collins and Jackie Green and Kathryn Ward and Peter Pereira and Rebecca Cusack and Anne Harrison and Aidan Lingwood and Alice Baker and Belinda Roberts and Eloise Summerton and Jonathan Biss and Karen Salmon and Elankumaran Paramasivam and Liz Wilby and Susan Trott and Zoe Friar and Biji Thomas and Kathy Brickell and Lorna Murphy and Niamh Mahon and Lindsey Woods and Sarah Cornell and Alex Zapata and Anna Rowena Reyes and Deborah Smyth and Georgia Bercades and Gladys Martir and Ingrid Hass and Laura Gallagher and Caroline Dooley and Hazel Smith and Lisa Moody and Matt Wise and Alice Swindell and Carl Hawkins and Geraldine Ward and John Laffey and Lauren Ferguson and Martina Carey and Ritu Negi and Dominic Strachan and Kirsten Moar and Suzanne Clements and Valerie Page and Elvira Hoxha and Xiao Bei Zhao and Andrew Bentley},
  year = {2026},
  journal = {The Lancet Respiratory Medicine},
  doi = {10.1016/s2213-2600(26)00040-8},
  url = {https://doi.org/10.1016/s2213-2600(26)00040-8}
}

RIS

TY  - JOUR
TI  - Bedside identification of subphenotypes in acute respiratory failure (PHIND): a multicentre, observational cohort study
AU  - Kiran Reddy
AU  - Pratik Sinha
AU  - David B Antcliffe
AU  - Clíona McDowell
AU  - Pauline A Bradley
AU  - Laura Black
AU  - Lynn Murphy
AU  - Judit Barbaras
AU  - John Conlon
AU  - Luigi Camporota
AU  - Marlies Ostermann
AU  - Phillip Hopkins
AU  - Tamas Szakmany
AU  - Shiney Cherian
AU  - Ingeborg Welters
AU  - David Brealey
AU  - Dhruv Parekh
AU  - Anthony J Rostron
AU  - Lieuwe D J Bos
AU  - Alistair Nichol
AU  - Manu Shankar-Hari
AU  - Anthony C Gordon
AU  - Kevin Delucchi
AU  - Cecilia M O'Kane
AU  - Michael A Matthay
AU  - Carolyn S Calfee
AU  - Daniel F McAuley
AU  - Barry Williams
AU  - Duncan Young
AU  - Maurice O'Kane
AU  - Christine McNally
AU  - Joanne Thompson
AU  - Judith McRory
AU  - Kevin Devlin
AU  - Lesley-Anne Dougan
AU  - Nuala Hannaway
AU  - Patricia Rafferty
AU  - Rejina Verghis
AU  - Roisin Thompson
AU  - Sean Reid
AU  - Peter Fitzgerald
AU  - Alisha Bothwell
AU  - Aoife McGreevy
AU  - Caolan Vaughan
AU  - Cecilia Fortugno
AU  - Huw Stacey
AU  - Jeremy Parker
AU  - John Lamont
AU  - Lauren Slater
AU  - Phil Robinson
AU  - Scott McKeown
AU  - Sophie McColgan
AU  - Ger Curley
AU  - Michelle Smyth
AU  - Sasha Keil
AU  - Gavin Perkins
AU  - Celinamma Maliaykal
AU  - Eleanor Reeves
AU  - Helen Taylor
AU  - Joanne Gresty
AU  - Lesley Horton
AU  - Teresa Melody
AU  - Will Leach
AU  - Nikitas Nikitas
AU  - Bethan Stowe
AU  - Elaine Freeman
AU  - Harry Lang
AU  - Helen McMillan
AU  - Kayleigh Spencer
AU  - Lauren Kimpton
AU  - Liana Stapleton
AU  - Michael Gillies
AU  - Matthew Faulds
AU  - Kathryn Puxty
AU  - Andrew Hurst
AU  - Callum Taylor
AU  - Dominic Rimmer
AU  - Beatriz Amaro de Jesus
AU  - Benjie Cendreda
AU  - Carolin Engelhard
AU  - Eirini Kosifidou
AU  - Eleanor Hendrie
AU  - Fabiola D'Amato
AU  - Gill Arbane
AU  - Kyma Morera
AU  - Sarah Fordyce
AU  - Shelley Lorah
AU  - Tahmina Matin
AU  - Caiomhe O'Dwyer
AU  - Maie Templeton
AU  - Roceld Rojo
AU  - Sonia Sousa Arias
AU  - Ziortza Fernandez de Pinedo Artaraz
AU  - Jeremy Henning
AU  - Burt Vergara
AU  - Clare Finney
AU  - Kevin O'Reilly
AU  - John Smith
AU  - Jonathan Bannard-Smith
AU  - Charlotte Taylor
AU  - Deborah Paripoorani
AU  - Katharine Wylie
AU  - Rachael Quayle
AU  - Richard Clark
AU  - Richard Innes
AU  - Amanda Groves
AU  - Ashly Thomas
AU  - Marc Chikhani
AU  - Alexandra Gibbins
AU  - Alice Baddeley
AU  - Alistair Morris
AU  - Anju Thomas
AU  - Catherine Walton
AU  - Cecilia Peters
AU  - David Ford
AU  - Julia Sampson
AU  - Stuart McKechnie
AU  - Grace Polley
AU  - Jean Wilson
AU  - Neil Davidson
AU  - Sally Beer
AU  - Brendan Sloan
AU  - Abigail Crew
AU  - Alexandra Metcalfe
AU  - Amy Major
AU  - Sarah Buckley
AU  - Dave Pogson
AU  - Andrew Walden
AU  - Haroon Waqar Uddin
AU  - Aayesha Kazi
AU  - Jillian Fitchett
AU  - Nicholas Truman
AU  - Michael Spivey
AU  - Carol Richards
AU  - Charlotte Barker Kirby
AU  - Eve Fletcher
AU  - Karen Burt
AU  - Kate Ralph
AU  - Rachel Chapman
AU  - Sarah Bean
AU  - Thomas Clark
AU  - Alexandra Carins
AU  - Arra Mahiya
AU  - David Shaw
AU  - Karen Williams
AU  - Maria Lopez Martinez
AU  - Maria Norris
AU  - Syamlan Ali
AU  - Victoria Waugh
AU  - Zachary Thomas
AU  - Aisling O'Neill
AU  - Chris Wright
AU  - Christine Turley
AU  - Erin Collins
AU  - Jackie Green
AU  - Kathryn Ward
AU  - Peter Pereira
AU  - Rebecca Cusack
AU  - Anne Harrison
AU  - Aidan Lingwood
AU  - Alice Baker
AU  - Belinda Roberts
AU  - Eloise Summerton
AU  - Jonathan Biss
AU  - Karen Salmon
AU  - Elankumaran Paramasivam
AU  - Liz Wilby
AU  - Susan Trott
AU  - Zoe Friar
AU  - Biji Thomas
AU  - Kathy Brickell
AU  - Lorna Murphy
AU  - Niamh Mahon
AU  - Lindsey Woods
AU  - Sarah Cornell
AU  - Alex Zapata
AU  - Anna Rowena Reyes
AU  - Deborah Smyth
AU  - Georgia Bercades
AU  - Gladys Martir
AU  - Ingrid Hass
AU  - Laura Gallagher
AU  - Caroline Dooley
AU  - Hazel Smith
AU  - Lisa Moody
AU  - Matt Wise
AU  - Alice Swindell
AU  - Carl Hawkins
AU  - Geraldine Ward
AU  - John Laffey
AU  - Lauren Ferguson
AU  - Martina Carey
AU  - Ritu Negi
AU  - Dominic Strachan
AU  - Kirsten Moar
AU  - Suzanne Clements
AU  - Valerie Page
AU  - Elvira Hoxha
AU  - Xiao Bei Zhao
AU  - Andrew Bentley
PY  - 2026
JO  - The Lancet Respiratory Medicine
DO  - 10.1016/s2213-2600(26)00040-8
UR  - https://doi.org/10.1016/s2213-2600(26)00040-8
ER  -

APA

Reddy, K., Sinha, P., Antcliffe, D. B., McDowell, C., Bradley, P. A., Black, L., Murphy, L., Barbaras, J., Conlon, J., Camporota, L., Ostermann, M., Hopkins, P., Szakmany, T., Cherian, S., Welters, I., Brealey, D., Parekh, D., Rostron, A. J., Bos, L. D. J., Nichol, A., Shankar-Hari, M., Gordon, A. C., Delucchi, K., O'Kane, C. M., Matthay, M. A., Calfee, C. S., McAuley, D. F., Williams, B., Young, D., O'Kane, M., McNally, C., Thompson, J., McRory, J., Devlin, K., Dougan, L., Hannaway, N., Rafferty, P., Verghis, R., Thompson, R., Reid, S., Fitzgerald, P., Bothwell, A., McGreevy, A., Vaughan, C., Fortugno, C., Stacey, H., Parker, J., Lamont, J., Slater, L., Robinson, P., McKeown, S., McColgan, S., Curley, G., Smyth, M., Keil, S., Perkins, G., Maliaykal, C., Reeves, E., Taylor, H., Gresty, J., Horton, L., Melody, T., Leach, W., Nikitas, N., Stowe, B., Freeman, E., Lang, H., McMillan, H., Spencer, K., Kimpton, L., Stapleton, L., Gillies, M., Faulds, M., Puxty, K., Hurst, A., Taylor, C., Rimmer, D., Jesus, B. A. D., Cendreda, B., Engelhard, C., Kosifidou, E., Hendrie, E., D'Amato, F., Arbane, G., Morera, K., Fordyce, S., Lorah, S., Matin, T., O'Dwyer, C., Templeton, M., Rojo, R., Arias, S. S., Artaraz, Z. F. D. P., Henning, J., Vergara, B., Finney, C., O'Reilly, K., Smith, J., Bannard-Smith, J., Taylor, C., Paripoorani, D., Wylie, K., Quayle, R., Clark, R., Innes, R., Groves, A., Thomas, A., Chikhani, M., Gibbins, A., Baddeley, A., Morris, A., Thomas, A., Walton, C., Peters, C., Ford, D., Sampson, J., McKechnie, S., Polley, G., Wilson, J., Davidson, N., Beer, S., Sloan, B., Crew, A., Metcalfe, A., Major, A., Buckley, S., Pogson, D., Walden, A., Uddin, H. W., Kazi, A., Fitchett, J., Truman, N., Spivey, M., Richards, C., Kirby, C. B., Fletcher, E., Burt, K., Ralph, K., Chapman, R., Bean, S., Clark, T., Carins, A., Mahiya, A., Shaw, D., Williams, K., Martinez, M. L., Norris, M., Ali, S., Waugh, V., Thomas, Z., O'Neill, A., Wright, C., Turley, C., Collins, E., Green, J., Ward, K., Pereira, P., Cusack, R., Harrison, A., Lingwood, A., Baker, A., Roberts, B., Summerton, E., Biss, J., Salmon, K., Paramasivam, E., Wilby, L., Trott, S., Friar, Z., Thomas, B., Brickell, K., Murphy, L., Mahon, N., Woods, L., Cornell, S., Zapata, A., Reyes, A. R., Smyth, D., Bercades, G., Martir, G., Hass, I., Gallagher, L., Dooley, C., Smith, H., Moody, L., Wise, M., Swindell, A., Hawkins, C., Ward, G., Laffey, J., Ferguson, L., Carey, M., Negi, R., Strachan, D., Moar, K., Clements, S., Page, V., Hoxha, E., Zhao, X. B., & Bentley, A. (2026). Bedside identification of subphenotypes in acute respiratory failure (PHIND): a multicentre, observational cohort study. The Lancet Respiratory Medicine. https://doi.org/10.1016/s2213-2600(26)00040-8

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crossref · retrieved 2026-09-26T01:56:15.767Z