Effectiveness of the RTS,S/AS01E malaria vaccine in a real-world setting over 1 year of follow-up after the three-dose primary schedule: an interim analysis of a phase 4 study in Ghana, Kenya, and Malawi

Latif Ndeketa, Valérie Haine, Muriel Debois, Kwaku Poku Asante, Prince Darko Agyapong, Seyram Kaali, Raghavendra Devadiga, Samuel B E Harrison, Owusu Boahen, Neil French, Kingsley Kayan, Bernhards Ogutu, Elisha Adeniji, Simon Kariuki, Seth Owusu-Agyei, Fredrick Olewe, Tikhala Makhaza Jere, Kenneth Maleta, Donnie Mategula, Phylis Mzanga, Vincent Katunga Phiri, Patrick Odum Ansah, John Orimbo, Nana Akosua Ansah, Mattea Orsini, John Michael Ong'echa, Abraham Rexford Oduro, Peter M Sifuna, Daniel K Azongo, Walter Otieno, Oscar Bangre, Michael Bandasua Kaburise, Lucy Osei Ababio, Janet Nyawira Oyieko, Valentine Sing'oei, Stellah Kevyne Amoit, Wongani Nyangulu, Lode Schuerman, Denis Awuni, Benard Omondi Ochieng, Irene Onyango, Patricia Odera-Ojwang, Esther Achieng Oguk, Yolanda Guerra Mendoza, Reuben Yego Cherop, George Odhiambo Okoth, Cristina Cravcenco, Raphael Chipatala, François Roman, Martina Oneko, Miloje Savic, Oscar Agyei, Joseph Ayimbila Ana-Aro, Seth Arthur, Cynthia Aton, Yvonne Afrah Berko, Dennis Bii, Miriam Chomba, David Dosoo, Clifford Kwarteng Kyeremateng, Jane Masinde, Paul Njika, James Nyagechanga, Angelina Odila, Daniel Omollo, Samuel Osei-Owusu, Sarah Otieno, Kephas Otieno, Daniel Ouko, Ronald Owino, Emmanuel Yirenkyi

Open source

DOI: 10.1016/s2214-109x(25)00415-2
Published: 2026-01
Container: The Lancet Global Health
Publisher: Elsevier BV
Open access: unknown

Credibility signals

uncertain Score 64/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

supportingDOI registered: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
supportingDOI resolves: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredOpen access status: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
supportingMetadata completeness: All 6 scored descriptive metadata groups are present. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1016/s2214-109x-25-00415-2,
  title = {Effectiveness of the RTS,S/AS01E malaria vaccine in a real-world setting over 1 year of follow-up after the three-dose primary schedule: an interim analysis of a phase 4 study in Ghana, Kenya, and Malawi},
  author = {Latif Ndeketa and Valérie Haine and Muriel Debois and Kwaku Poku Asante and Prince Darko Agyapong and Seyram Kaali and Raghavendra Devadiga and Samuel B E Harrison and Owusu Boahen and Neil French and Kingsley Kayan and Bernhards Ogutu and Elisha Adeniji and Simon Kariuki and Seth Owusu-Agyei and Fredrick Olewe and Tikhala Makhaza Jere and Kenneth Maleta and Donnie Mategula and Phylis Mzanga and Vincent Katunga Phiri and Patrick Odum Ansah and John Orimbo and Nana Akosua Ansah and Mattea Orsini and John Michael Ong'echa and Abraham Rexford Oduro and Peter M Sifuna and Daniel K Azongo and Walter Otieno and Oscar Bangre and Michael Bandasua Kaburise and Lucy Osei Ababio and Janet Nyawira Oyieko and Valentine Sing'oei and Stellah Kevyne Amoit and Wongani Nyangulu and Lode Schuerman and Denis Awuni and Benard Omondi Ochieng and Irene Onyango and Patricia Odera-Ojwang and Esther Achieng Oguk and Yolanda Guerra Mendoza and Reuben Yego Cherop and George Odhiambo Okoth and Cristina Cravcenco and Raphael Chipatala and François Roman and Martina Oneko and Miloje Savic and Oscar Agyei and Joseph Ayimbila Ana-Aro and Seth Arthur and Cynthia Aton and Yvonne Afrah Berko and Dennis Bii and Miriam Chomba and David Dosoo and Clifford Kwarteng Kyeremateng and Jane Masinde and Paul Njika and James Nyagechanga and Angelina Odila and Daniel Omollo and Samuel Osei-Owusu and Sarah Otieno and Kephas Otieno and Daniel Ouko and Ronald Owino and Emmanuel Yirenkyi},
  year = {2026},
  journal = {The Lancet Global Health},
  doi = {10.1016/s2214-109x(25)00415-2},
  url = {https://doi.org/10.1016/s2214-109x(25)00415-2}
}

RIS

TY  - JOUR
TI  - Effectiveness of the RTS,S/AS01E malaria vaccine in a real-world setting over 1 year of follow-up after the three-dose primary schedule: an interim analysis of a phase 4 study in Ghana, Kenya, and Malawi
AU  - Latif Ndeketa
AU  - Valérie Haine
AU  - Muriel Debois
AU  - Kwaku Poku Asante
AU  - Prince Darko Agyapong
AU  - Seyram Kaali
AU  - Raghavendra Devadiga
AU  - Samuel B E Harrison
AU  - Owusu Boahen
AU  - Neil French
AU  - Kingsley Kayan
AU  - Bernhards Ogutu
AU  - Elisha Adeniji
AU  - Simon Kariuki
AU  - Seth Owusu-Agyei
AU  - Fredrick Olewe
AU  - Tikhala Makhaza Jere
AU  - Kenneth Maleta
AU  - Donnie Mategula
AU  - Phylis Mzanga
AU  - Vincent Katunga Phiri
AU  - Patrick Odum Ansah
AU  - John Orimbo
AU  - Nana Akosua Ansah
AU  - Mattea Orsini
AU  - John Michael Ong'echa
AU  - Abraham Rexford Oduro
AU  - Peter M Sifuna
AU  - Daniel K Azongo
AU  - Walter Otieno
AU  - Oscar Bangre
AU  - Michael Bandasua Kaburise
AU  - Lucy Osei Ababio
AU  - Janet Nyawira Oyieko
AU  - Valentine Sing'oei
AU  - Stellah Kevyne Amoit
AU  - Wongani Nyangulu
AU  - Lode Schuerman
AU  - Denis Awuni
AU  - Benard Omondi Ochieng
AU  - Irene Onyango
AU  - Patricia Odera-Ojwang
AU  - Esther Achieng Oguk
AU  - Yolanda Guerra Mendoza
AU  - Reuben Yego Cherop
AU  - George Odhiambo Okoth
AU  - Cristina Cravcenco
AU  - Raphael Chipatala
AU  - François Roman
AU  - Martina Oneko
AU  - Miloje Savic
AU  - Oscar Agyei
AU  - Joseph Ayimbila Ana-Aro
AU  - Seth Arthur
AU  - Cynthia Aton
AU  - Yvonne Afrah Berko
AU  - Dennis Bii
AU  - Miriam Chomba
AU  - David Dosoo
AU  - Clifford Kwarteng Kyeremateng
AU  - Jane Masinde
AU  - Paul Njika
AU  - James Nyagechanga
AU  - Angelina Odila
AU  - Daniel Omollo
AU  - Samuel Osei-Owusu
AU  - Sarah Otieno
AU  - Kephas Otieno
AU  - Daniel Ouko
AU  - Ronald Owino
AU  - Emmanuel Yirenkyi
PY  - 2026
JO  - The Lancet Global Health
DO  - 10.1016/s2214-109x(25)00415-2
UR  - https://doi.org/10.1016/s2214-109x(25)00415-2
ER  -

APA

Ndeketa, L., Haine, V., Debois, M., Asante, K. P., Agyapong, P. D., Kaali, S., Devadiga, R., Harrison, S. B. E., Boahen, O., French, N., Kayan, K., Ogutu, B., Adeniji, E., Kariuki, S., Owusu-Agyei, S., Olewe, F., Jere, T. M., Maleta, K., Mategula, D., Mzanga, P., Phiri, V. K., Ansah, P. O., Orimbo, J., Ansah, N. A., Orsini, M., Ong'echa, J. M., Oduro, A. R., Sifuna, P. M., Azongo, D. K., Otieno, W., Bangre, O., Kaburise, M. B., Ababio, L. O., Oyieko, J. N., Sing'oei, V., Amoit, S. K., Nyangulu, W., Schuerman, L., Awuni, D., Ochieng, B. O., Onyango, I., Odera-Ojwang, P., Oguk, E. A., Mendoza, Y. G., Cherop, R. Y., Okoth, G. O., Cravcenco, C., Chipatala, R., Roman, F., Oneko, M., Savic, M., Agyei, O., Ana-Aro, J. A., Arthur, S., Aton, C., Berko, Y. A., Bii, D., Chomba, M., Dosoo, D., Kyeremateng, C. K., Masinde, J., Njika, P., Nyagechanga, J., Odila, A., Omollo, D., Osei-Owusu, S., Otieno, S., Otieno, K., Ouko, D., Owino, R., & Yirenkyi, E. (2026). Effectiveness of the RTS,S/AS01E malaria vaccine in a real-world setting over 1 year of follow-up after the three-dose primary schedule: an interim analysis of a phase 4 study in Ghana, Kenya, and Malawi. The Lancet Global Health. https://doi.org/10.1016/s2214-109x(25)00415-2

Source records

crossref · retrieved 2026-09-26T05:52:25.889Z