Comparative effectiveness of mood stabiliser monotherapy versus second-generation antipsychotic monotherapy versus combination therapy for continuation and maintenance treatment after a first episode of psychotic mania in North America, Chile, and Spain: a target trial emulation using data from the BD-CAUSAL Collaboration

Alejandro G Szmulewicz, Yu-Hsin Liang, Gonzalo Martínez-Alés, Ryan O’Dea, Lorna E Thorpe, Sarah Conderino, José M Rubio, Kerry Smith, Deepak K Sarpal, Covadonga M Díaz-Caneja, Celso Arango, Paul A Vöhringer, Sophia A Aldunate, Ridha Joober, Jai L Shah, Ashok Malla, Diane Fredrikson, Lakshmi N Yatham, Miguel A Hernán, Dost Öngür, Ann Shinn, Joaquín Galvañ, Marina Díaz-Marsá, José Luis Ayuso-Mateos, Ángela Ibáñez, Roberto Rodríguez-Jiménez, Ainoa Muñoz-Sanjosé, María-Fe Bravo-Ortíz, Enrique Baca-García, Juan Gago, Michael Birnbaum, Kristin Candan, Philipp Watson, John Kane, Christian Kelly, Srividya Iyer, Martin Lepage, Kamyar Keramatian

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DOI
10.1016/s2215-0366(26)00239-7
Published
2026-10
Container
The Lancet Psychiatry
Publisher
Elsevier BV
Open access
unknown

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BibTeX

@article{allodium:10.1016/s2215-0366-26-00239-7,
  title = {Comparative effectiveness of mood stabiliser monotherapy versus second-generation antipsychotic monotherapy versus combination therapy for continuation and maintenance treatment after a first episode of psychotic mania in North America, Chile, and Spain: a target trial emulation using data from the BD-CAUSAL Collaboration},
  author = {Alejandro G Szmulewicz and Yu-Hsin Liang and Gonzalo Martínez-Alés and Ryan O’Dea and Lorna E Thorpe and Sarah Conderino and José M Rubio and Kerry Smith and Deepak K Sarpal and Covadonga M Díaz-Caneja and Celso Arango and Paul A Vöhringer and Sophia A Aldunate and Ridha Joober and Jai L Shah and Ashok Malla and Diane Fredrikson and Lakshmi N Yatham and Miguel A Hernán and Dost Öngür and Ann Shinn and Joaquín Galvañ and Marina Díaz-Marsá and José Luis Ayuso-Mateos and Ángela Ibáñez and Roberto Rodríguez-Jiménez and Ainoa Muñoz-Sanjosé and María-Fe Bravo-Ortíz and Enrique Baca-García and Juan Gago and Michael Birnbaum and Kristin Candan and Philipp Watson and John Kane and Christian Kelly and Srividya Iyer and Martin Lepage and Kamyar Keramatian},
  year = {2026},
  journal = {The Lancet Psychiatry},
  doi = {10.1016/s2215-0366(26)00239-7},
  url = {https://doi.org/10.1016/s2215-0366(26)00239-7}
}

RIS

TY  - JOUR
TI  - Comparative effectiveness of mood stabiliser monotherapy versus second-generation antipsychotic monotherapy versus combination therapy for continuation and maintenance treatment after a first episode of psychotic mania in North America, Chile, and Spain: a target trial emulation using data from the BD-CAUSAL Collaboration
AU  - Alejandro G Szmulewicz
AU  - Yu-Hsin Liang
AU  - Gonzalo Martínez-Alés
AU  - Ryan O’Dea
AU  - Lorna E Thorpe
AU  - Sarah Conderino
AU  - José M Rubio
AU  - Kerry Smith
AU  - Deepak K Sarpal
AU  - Covadonga M Díaz-Caneja
AU  - Celso Arango
AU  - Paul A Vöhringer
AU  - Sophia A Aldunate
AU  - Ridha Joober
AU  - Jai L Shah
AU  - Ashok Malla
AU  - Diane Fredrikson
AU  - Lakshmi N Yatham
AU  - Miguel A Hernán
AU  - Dost Öngür
AU  - Ann Shinn
AU  - Joaquín Galvañ
AU  - Marina Díaz-Marsá
AU  - José Luis Ayuso-Mateos
AU  - Ángela Ibáñez
AU  - Roberto Rodríguez-Jiménez
AU  - Ainoa Muñoz-Sanjosé
AU  - María-Fe Bravo-Ortíz
AU  - Enrique Baca-García
AU  - Juan Gago
AU  - Michael Birnbaum
AU  - Kristin Candan
AU  - Philipp Watson
AU  - John Kane
AU  - Christian Kelly
AU  - Srividya Iyer
AU  - Martin Lepage
AU  - Kamyar Keramatian
PY  - 2026
JO  - The Lancet Psychiatry
DO  - 10.1016/s2215-0366(26)00239-7
UR  - https://doi.org/10.1016/s2215-0366(26)00239-7
ER  - 

APA

Szmulewicz, A. G., Liang, Y., Martínez-Alés, G., O’Dea, R., Thorpe, L. E., Conderino, S., Rubio, J. M., Smith, K., Sarpal, D. K., Díaz-Caneja, C. M., Arango, C., Vöhringer, P. A., Aldunate, S. A., Joober, R., Shah, J. L., Malla, A., Fredrikson, D., Yatham, L. N., Hernán, M. A., Öngür, D., Shinn, A., Galvañ, J., Díaz-Marsá, M., Ayuso-Mateos, J. L., Ibáñez, Á., Rodríguez-Jiménez, R., Muñoz-Sanjosé, A., Bravo-Ortíz, M., Baca-García, E., Gago, J., Birnbaum, M., Candan, K., Watson, P., Kane, J., Kelly, C., Iyer, S., Lepage, M., & Keramatian, K. (2026). Comparative effectiveness of mood stabiliser monotherapy versus second-generation antipsychotic monotherapy versus combination therapy for continuation and maintenance treatment after a first episode of psychotic mania in North America, Chile, and Spain: a target trial emulation using data from the BD-CAUSAL Collaboration. The Lancet Psychiatry. https://doi.org/10.1016/s2215-0366(26)00239-7

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