Safety and pharmacokinetics of N6LS, a broadly neutralising monoclonal antibody for HIV: a phase 1, open-label, dose-escalation study in healthy adults.

Wu RL, Houser KV, Gaudinski MR, Widge AT, Awan SF, Carter CA, Holman LA, Saunders J, Hendel CS, Eshun A, Whalen WR, Wang X, Arthur A, Cunningham JE, Beck A, Casazza JP, Yamshchikov GV, Rothwell RS, Strom L, Dittakavi T, Happe M, Hickman SP, Conan-Cibotti M, Carlton K, Zhang L, Huang Y, Capparelli EV, Castro M, Lin BC, O'Connell S, Flach BS, Bailer RT, Narpala SR, Serebryannyy L, McDermott AB, Arnold FJ, Gall JG, Vazquez S, Berkowitz NM, Gordon IJ, Chen GL, Kwong PD, Huang J, Pierson TC, Connors M, Mascola JR, Zhou T, Doria-Rose NA, Koup RA, Dropulic LK, VRC 609 study team

Open source

DOI
10.1016/s2352-3018(25)00041-4
Published
2025 Jul
Container
The lancet. HIV
Publisher
Not recorded
Open access
yes

Credibility signals

limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

Cite this work

BibTeX

@article{allodium:10.1016/s2352-3018-25-00041-4,
  title = {Safety and pharmacokinetics of N6LS, a broadly neutralising monoclonal antibody for HIV: a phase 1, open-label, dose-escalation study in healthy adults.},
  author = {Wu RL and Houser KV and Gaudinski MR and Widge AT and Awan SF and Carter CA and Holman LA and Saunders J and Hendel CS and Eshun A and Whalen WR and Wang X and Arthur A and Cunningham JE and Beck A and Casazza JP and Yamshchikov GV and Rothwell RS and Strom L and Dittakavi T and Happe M and Hickman SP and Conan-Cibotti M and Carlton K and Zhang L and Huang Y and Capparelli EV and Castro M and Lin BC and O'Connell S and Flach BS and Bailer RT and Narpala SR and Serebryannyy L and McDermott AB and Arnold FJ and Gall JG and Vazquez S and Berkowitz NM and Gordon IJ and Chen GL and Kwong PD and Huang J and Pierson TC and Connors M and Mascola JR and Zhou T and Doria-Rose NA and Koup RA and Dropulic LK and VRC 609 study team},
  year = {2025},
  journal = {The lancet. HIV},
  doi = {10.1016/s2352-3018(25)00041-4},
  url = {https://doi.org/10.1016/s2352-3018(25)00041-4}
}

RIS

TY  - JOUR
TI  - Safety and pharmacokinetics of N6LS, a broadly neutralising monoclonal antibody for HIV: a phase 1, open-label, dose-escalation study in healthy adults.
AU  - Wu RL
AU  - Houser KV
AU  - Gaudinski MR
AU  - Widge AT
AU  - Awan SF
AU  - Carter CA
AU  - Holman LA
AU  - Saunders J
AU  - Hendel CS
AU  - Eshun A
AU  - Whalen WR
AU  - Wang X
AU  - Arthur A
AU  - Cunningham JE
AU  - Beck A
AU  - Casazza JP
AU  - Yamshchikov GV
AU  - Rothwell RS
AU  - Strom L
AU  - Dittakavi T
AU  - Happe M
AU  - Hickman SP
AU  - Conan-Cibotti M
AU  - Carlton K
AU  - Zhang L
AU  - Huang Y
AU  - Capparelli EV
AU  - Castro M
AU  - Lin BC
AU  - O'Connell S
AU  - Flach BS
AU  - Bailer RT
AU  - Narpala SR
AU  - Serebryannyy L
AU  - McDermott AB
AU  - Arnold FJ
AU  - Gall JG
AU  - Vazquez S
AU  - Berkowitz NM
AU  - Gordon IJ
AU  - Chen GL
AU  - Kwong PD
AU  - Huang J
AU  - Pierson TC
AU  - Connors M
AU  - Mascola JR
AU  - Zhou T
AU  - Doria-Rose NA
AU  - Koup RA
AU  - Dropulic LK
AU  - VRC 609 study team
PY  - 2025
JO  - The lancet. HIV
DO  - 10.1016/s2352-3018(25)00041-4
UR  - https://doi.org/10.1016/s2352-3018(25)00041-4
ER  -

APA

RL, W., KV, H., MR, G., AT, W., SF, A., CA, C., LA, H., J, S., CS, H., A, E., WR, W., X, W., A, A., JE, C., A, B., JP, C., GV, Y., RS, R., L, S., T, D., M, H., SP, H., M, C., K, C., L, Z., Y, H., EV, C., M, C., BC, L., S, O., BS, F., RT, B., SR, N., L, S., AB, M., FJ, A., JG, G., S, V., NM, B., IJ, G., GL, C., PD, K., J, H., TC, P., M, C., JR, M., T, Z., NA, D., RA, K., LK, D., & team, V. 6. S. (2025). Safety and pharmacokinetics of N6LS, a broadly neutralising monoclonal antibody for HIV: a phase 1, open-label, dose-escalation study in healthy adults.. The lancet. HIV. https://doi.org/10.1016/s2352-3018(25)00041-4

Source records