Age distribution of respiratory syncytial virus disease in children younger than 5 years in low-income and middle-income countries: a systematic review and meta-analysis

Sarwat Mahmud, Kevin van Zandvoort, Ling Guo, You Li, Harish Nair, Daniel R Feikin, Erin Sparrow, Fahmida Chowdhury, Cheryl Cohen, Ghassan S Dbaibo, Angela Gentile, Christopher J Gill, Aubree Gordon, Katherine C Horton, Qing Cao, Kirill Stolyarov, Andrew D Clark, Charles N. Agoti, Víctor Ahumada-Topete, Suha Ali, Syed Asad Ali, Montaha Al-Iede, Arwa Al-Shuwaikh, Suresh Kumar Angurana, Martin Antonio, Hala Arif, Lourdes Arruvito, Samah Awad, Angel Balmaseda, Ranju Baral, Amina Barkat, Naor Bar-Zeev, Quique Bassat, Benan Bayrakci, Eduardo Becerril-Vargas, Godfrey Bigogo, Abderrahman Bimouhen, Champica Bodinayake, Louis Bont, Celina F. Boutros, Yarisa Sujey Brizuela, W. Abdullah Brooks, Jackrapong Bruminhent, Alfredo Bruno C., Andrea Buchwald, Charatdao Bunthi, Mauricio T. Caballero, Saverio Caini, Ana Carlotti, Juan Miguel Castillo, Armando Roberto Castorena-Maldonado, Nathorn Chaiyakunapruk, Sara Chandy, Helen Y. Chu, Daria Danilenko, Joanne de Jesus, Tirza de Leon, Domenica de Mora, Juana del Valle Mendoza, Jikui Deng, Joseph Domachowske, Amanda Driscoll, Julia Dvorkin, Marcela Echavarria, Brian Eley, Monica Escobar, Dora Estripeaut, Fernando Ferrero, Stefan Flasche, Leah Forman, Danilo Franco, Felipe Teixeira de Mello Freitas, Collrane Frivold, Yuki Furuse, Maria Ahuoiza Garba, Jorge Raul Garcia-Corzo, Cristina Garcia-Mauriño, Jorge Geffner, Yazmin Godinez-Zavala, Rosalba Gonzalez, Doli R Goswami, Lionel Gresh, Carlos G Grijalva, Gonzalo Guiñazú, Rima Hanna Wakim, Fatimata Hassane, Kenza Hattoufi, Carmen Margarita Hernández-Cárdenas, Melissa Higdon, Anusha Hindupur, Maria Pia Holgado, Stephen R.C. Howie, Judith M. Hübschen, Olayinka Oluwatoyin Idris, Heloisa Ihle Garcia Giamberardino, Md Ariful Islam, Mohammad Shahidul Islam, Moussa Issa, Jorge Jara, Raquel Jara, Wujun Jiang, María del Valle Juarez, Sophie Jullien, Everlyn Kamau, Esther Katama, Matthew S Kelly, Win Khaing, Maria Deloria Knoll, Esra Kockuzu, Olatunji Matthew Kolawole, Giscard F. Komoyo, Karen Kotloff, Parvaiz A Koul, Anand Krishnan, John Kubale, Rakesh Kumar, Ruvini Kurukulasooriya, Adamou Lagare, Asmae Lamrani Hanchi, Claudio F Lanata, Joanne M. Langley, Low Yoke Lee, Se Li, Wenkuan Liu, Guwani Liyanage, Maria Londono-Avendano, Lu Lu, Kathia Luciani, María Florencia Lucion, Grant Mackenzie, William MacLeod, Mohammad Abdullah Mahmud, Rungnapa Malasao, Anand Manoharan, Leana Maree, Thangam Menon, Talat Mokhtari-Azad, Shaun K. Morris, Brenda M. Morrow, Jocelyn Moyes, Tufária Mussá, Martin Mutunga, Lawrence Mwananyanda, Ajith Nagahawatte, Sharifa Nasreen, Mark P Nicol, James Nokes, François Nosten, Daniel E. Noyola, Joyce Nyiro, Evangeline Obodai, Michiko Okamoto, Regina Oladokun, Hitoshi Oshitani, Juliet Otieno, Mirela Pale, Chanthawat Patikorn, Rachel Pieciak, Maria Pisareva, Angelica Margarita Portillo-Vasquez, Christine Prosperi, Sonia Mara Raboni, Mohammad Ziaur Rahman, Silvina Raiden, Neele Rave, Noelia S. Reyes, Samir K. Saha, Senjuti Saha, Vahid Salimi, Ines Sananez, Felix Sanchez, Charles Sande, Anthony Scott, Sharona Seetharam, Philip Seidenberg, Farina Shaaban, Edgar Simulundu, Chantal J. Snoeck, Fabricia Sobrinho, Samba Sow, Klaita Srisingh, Manika Suryadevara, Catherine G. Sutcliffe, Chia Jie Tan, Miligratos Tapia, Forough Tavakoli, Chonnamet Techasaensiri, Don M. Thea, L. Gayani Tillekeratne, Houssain Tligui, Paul Turner, Sky Vanderburg, Joel Armando Vázquez-Pérez, Femke Vernooij, Sandra E. Vieira, Anne von Gottberg, Richard Wachepa, Sibongile Walaza, Wanitda Watthanaworawit, Gaya Wijayaratne, Jonas Michel Wolf, Kon Ken Wong, Qing Ye, Lay-Myint Yoshida, Mohammad Tahir Yousafzai, Anita Zaidi, Khalequ Zaman, Heather J Zar, Qianye Zhao

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DOI
10.1016/s2352-4642(25)00349-9
Published
2026-04
Container
The Lancet Child & Adolescent Health
Publisher
Elsevier BV
Open access
unknown

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@article{allodium:10.1016/s2352-4642-25-00349-9,
  title = {Age distribution of respiratory syncytial virus disease in children younger than 5 years in low-income and middle-income countries: a systematic review and meta-analysis},
  author = {Sarwat Mahmud and Kevin van Zandvoort and Ling Guo and You Li and Harish Nair and Daniel R Feikin and Erin Sparrow and Fahmida Chowdhury and Cheryl Cohen and Ghassan S Dbaibo and Angela Gentile and Christopher J Gill and Aubree Gordon and Katherine C Horton and Qing Cao and Kirill Stolyarov and Andrew D Clark and Charles N. Agoti and Víctor Ahumada-Topete and Suha Ali and Syed Asad Ali and Montaha Al-Iede and Arwa Al-Shuwaikh and Suresh Kumar Angurana and Martin Antonio and Hala Arif and Lourdes Arruvito and Samah Awad and Angel Balmaseda and Ranju Baral and Amina Barkat and Naor Bar-Zeev and Quique Bassat and Benan Bayrakci and Eduardo Becerril-Vargas and Godfrey Bigogo and Abderrahman Bimouhen and Champica Bodinayake and Louis Bont and Celina F. Boutros and Yarisa Sujey Brizuela and W. Abdullah Brooks and Jackrapong Bruminhent and Alfredo Bruno C. and Andrea Buchwald and Charatdao Bunthi and Mauricio T. Caballero and Saverio Caini and Ana Carlotti and Juan Miguel Castillo and Armando Roberto Castorena-Maldonado and Nathorn Chaiyakunapruk and Sara Chandy and Helen Y. Chu and Daria Danilenko and Joanne de Jesus and Tirza de Leon and Domenica de Mora and Juana del Valle Mendoza and Jikui Deng and Joseph Domachowske and Amanda Driscoll and Julia Dvorkin and Marcela Echavarria and Brian Eley and Monica Escobar and Dora Estripeaut and Fernando Ferrero and Stefan Flasche and Leah Forman and Danilo Franco and Felipe Teixeira de Mello Freitas and Collrane Frivold and Yuki Furuse and Maria Ahuoiza Garba and Jorge Raul Garcia-Corzo and Cristina Garcia-Mauriño and Jorge Geffner and Yazmin Godinez-Zavala and Rosalba Gonzalez and Doli R Goswami and Lionel Gresh and Carlos G Grijalva and Gonzalo Guiñazú and Rima Hanna Wakim and Fatimata Hassane and Kenza Hattoufi and Carmen Margarita Hernández-Cárdenas and Melissa Higdon and Anusha Hindupur and Maria Pia Holgado and Stephen R.C. Howie and Judith M. Hübschen and Olayinka Oluwatoyin Idris and Heloisa Ihle Garcia Giamberardino and Md Ariful Islam and Mohammad Shahidul Islam and Moussa Issa and Jorge Jara and Raquel Jara and Wujun Jiang and María del Valle Juarez and Sophie Jullien and Everlyn Kamau and Esther Katama and Matthew S Kelly and Win Khaing and Maria Deloria Knoll and Esra Kockuzu and Olatunji Matthew Kolawole and Giscard F. Komoyo and Karen Kotloff and Parvaiz A Koul and Anand Krishnan and John Kubale and Rakesh Kumar and Ruvini Kurukulasooriya and Adamou Lagare and Asmae Lamrani Hanchi and Claudio F Lanata and Joanne M. Langley and Low Yoke Lee and Se Li and Wenkuan Liu and Guwani Liyanage and Maria Londono-Avendano and Lu Lu and Kathia Luciani and María Florencia Lucion and Grant Mackenzie and William MacLeod and Mohammad Abdullah Mahmud and Rungnapa Malasao and Anand Manoharan and Leana Maree and Thangam Menon and Talat Mokhtari-Azad and Shaun K. Morris and Brenda M. Morrow and Jocelyn Moyes and Tufária Mussá and Martin Mutunga and Lawrence Mwananyanda and Ajith Nagahawatte and Sharifa Nasreen and Mark P Nicol and James Nokes and François Nosten and Daniel E. Noyola and Joyce Nyiro and Evangeline Obodai and Michiko Okamoto and Regina Oladokun and Hitoshi Oshitani and Juliet Otieno and Mirela Pale and Chanthawat Patikorn and Rachel Pieciak and Maria Pisareva and Angelica Margarita Portillo-Vasquez and Christine Prosperi and Sonia Mara Raboni and Mohammad Ziaur Rahman and Silvina Raiden and Neele Rave and Noelia S. Reyes and Samir K. Saha and Senjuti Saha and Vahid Salimi and Ines Sananez and Felix Sanchez and Charles Sande and Anthony Scott and Sharona Seetharam and Philip Seidenberg and Farina Shaaban and Edgar Simulundu and Chantal J. Snoeck and Fabricia Sobrinho and Samba Sow and Klaita Srisingh and Manika Suryadevara and Catherine G. Sutcliffe and Chia Jie Tan and Miligratos Tapia and Forough Tavakoli and Chonnamet Techasaensiri and Don M. Thea and L. Gayani Tillekeratne and Houssain Tligui and Paul Turner and Sky Vanderburg and Joel Armando Vázquez-Pérez and Femke Vernooij and Sandra E. Vieira and Anne von Gottberg and Richard Wachepa and Sibongile Walaza and Wanitda Watthanaworawit and Gaya Wijayaratne and Jonas Michel Wolf and Kon Ken Wong and Qing Ye and Lay-Myint Yoshida and Mohammad Tahir Yousafzai and Anita Zaidi and Khalequ Zaman and Heather J Zar and Qianye Zhao},
  year = {2026},
  journal = {The Lancet Child \& Adolescent Health},
  doi = {10.1016/s2352-4642(25)00349-9},
  url = {https://doi.org/10.1016/s2352-4642(25)00349-9}
}

RIS

TY  - JOUR
TI  - Age distribution of respiratory syncytial virus disease in children younger than 5 years in low-income and middle-income countries: a systematic review and meta-analysis
AU  - Sarwat Mahmud
AU  - Kevin van Zandvoort
AU  - Ling Guo
AU  - You Li
AU  - Harish Nair
AU  - Daniel R Feikin
AU  - Erin Sparrow
AU  - Fahmida Chowdhury
AU  - Cheryl Cohen
AU  - Ghassan S Dbaibo
AU  - Angela Gentile
AU  - Christopher J Gill
AU  - Aubree Gordon
AU  - Katherine C Horton
AU  - Qing Cao
AU  - Kirill Stolyarov
AU  - Andrew D Clark
AU  - Charles N. Agoti
AU  - Víctor Ahumada-Topete
AU  - Suha Ali
AU  - Syed Asad Ali
AU  - Montaha Al-Iede
AU  - Arwa Al-Shuwaikh
AU  - Suresh Kumar Angurana
AU  - Martin Antonio
AU  - Hala Arif
AU  - Lourdes Arruvito
AU  - Samah Awad
AU  - Angel Balmaseda
AU  - Ranju Baral
AU  - Amina Barkat
AU  - Naor Bar-Zeev
AU  - Quique Bassat
AU  - Benan Bayrakci
AU  - Eduardo Becerril-Vargas
AU  - Godfrey Bigogo
AU  - Abderrahman Bimouhen
AU  - Champica Bodinayake
AU  - Louis Bont
AU  - Celina F. Boutros
AU  - Yarisa Sujey Brizuela
AU  - W. Abdullah Brooks
AU  - Jackrapong Bruminhent
AU  - Alfredo Bruno C.
AU  - Andrea Buchwald
AU  - Charatdao Bunthi
AU  - Mauricio T. Caballero
AU  - Saverio Caini
AU  - Ana Carlotti
AU  - Juan Miguel Castillo
AU  - Armando Roberto Castorena-Maldonado
AU  - Nathorn Chaiyakunapruk
AU  - Sara Chandy
AU  - Helen Y. Chu
AU  - Daria Danilenko
AU  - Joanne de Jesus
AU  - Tirza de Leon
AU  - Domenica de Mora
AU  - Juana del Valle Mendoza
AU  - Jikui Deng
AU  - Joseph Domachowske
AU  - Amanda Driscoll
AU  - Julia Dvorkin
AU  - Marcela Echavarria
AU  - Brian Eley
AU  - Monica Escobar
AU  - Dora Estripeaut
AU  - Fernando Ferrero
AU  - Stefan Flasche
AU  - Leah Forman
AU  - Danilo Franco
AU  - Felipe Teixeira de Mello Freitas
AU  - Collrane Frivold
AU  - Yuki Furuse
AU  - Maria Ahuoiza Garba
AU  - Jorge Raul Garcia-Corzo
AU  - Cristina Garcia-Mauriño
AU  - Jorge Geffner
AU  - Yazmin Godinez-Zavala
AU  - Rosalba Gonzalez
AU  - Doli R Goswami
AU  - Lionel Gresh
AU  - Carlos G Grijalva
AU  - Gonzalo Guiñazú
AU  - Rima Hanna Wakim
AU  - Fatimata Hassane
AU  - Kenza Hattoufi
AU  - Carmen Margarita Hernández-Cárdenas
AU  - Melissa Higdon
AU  - Anusha Hindupur
AU  - Maria Pia Holgado
AU  - Stephen R.C. Howie
AU  - Judith M. Hübschen
AU  - Olayinka Oluwatoyin Idris
AU  - Heloisa Ihle Garcia Giamberardino
AU  - Md Ariful Islam
AU  - Mohammad Shahidul Islam
AU  - Moussa Issa
AU  - Jorge Jara
AU  - Raquel Jara
AU  - Wujun Jiang
AU  - María del Valle Juarez
AU  - Sophie Jullien
AU  - Everlyn Kamau
AU  - Esther Katama
AU  - Matthew S Kelly
AU  - Win Khaing
AU  - Maria Deloria Knoll
AU  - Esra Kockuzu
AU  - Olatunji Matthew Kolawole
AU  - Giscard F. Komoyo
AU  - Karen Kotloff
AU  - Parvaiz A Koul
AU  - Anand Krishnan
AU  - John Kubale
AU  - Rakesh Kumar
AU  - Ruvini Kurukulasooriya
AU  - Adamou Lagare
AU  - Asmae Lamrani Hanchi
AU  - Claudio F Lanata
AU  - Joanne M. Langley
AU  - Low Yoke Lee
AU  - Se Li
AU  - Wenkuan Liu
AU  - Guwani Liyanage
AU  - Maria Londono-Avendano
AU  - Lu Lu
AU  - Kathia Luciani
AU  - María Florencia Lucion
AU  - Grant Mackenzie
AU  - William MacLeod
AU  - Mohammad Abdullah Mahmud
AU  - Rungnapa Malasao
AU  - Anand Manoharan
AU  - Leana Maree
AU  - Thangam Menon
AU  - Talat Mokhtari-Azad
AU  - Shaun K. Morris
AU  - Brenda M. Morrow
AU  - Jocelyn Moyes
AU  - Tufária Mussá
AU  - Martin Mutunga
AU  - Lawrence Mwananyanda
AU  - Ajith Nagahawatte
AU  - Sharifa Nasreen
AU  - Mark P Nicol
AU  - James Nokes
AU  - François Nosten
AU  - Daniel E. Noyola
AU  - Joyce Nyiro
AU  - Evangeline Obodai
AU  - Michiko Okamoto
AU  - Regina Oladokun
AU  - Hitoshi Oshitani
AU  - Juliet Otieno
AU  - Mirela Pale
AU  - Chanthawat Patikorn
AU  - Rachel Pieciak
AU  - Maria Pisareva
AU  - Angelica Margarita Portillo-Vasquez
AU  - Christine Prosperi
AU  - Sonia Mara Raboni
AU  - Mohammad Ziaur Rahman
AU  - Silvina Raiden
AU  - Neele Rave
AU  - Noelia S. Reyes
AU  - Samir K. Saha
AU  - Senjuti Saha
AU  - Vahid Salimi
AU  - Ines Sananez
AU  - Felix Sanchez
AU  - Charles Sande
AU  - Anthony Scott
AU  - Sharona Seetharam
AU  - Philip Seidenberg
AU  - Farina Shaaban
AU  - Edgar Simulundu
AU  - Chantal J. Snoeck
AU  - Fabricia Sobrinho
AU  - Samba Sow
AU  - Klaita Srisingh
AU  - Manika Suryadevara
AU  - Catherine G. Sutcliffe
AU  - Chia Jie Tan
AU  - Miligratos Tapia
AU  - Forough Tavakoli
AU  - Chonnamet Techasaensiri
AU  - Don M. Thea
AU  - L. Gayani Tillekeratne
AU  - Houssain Tligui
AU  - Paul Turner
AU  - Sky Vanderburg
AU  - Joel Armando Vázquez-Pérez
AU  - Femke Vernooij
AU  - Sandra E. Vieira
AU  - Anne von Gottberg
AU  - Richard Wachepa
AU  - Sibongile Walaza
AU  - Wanitda Watthanaworawit
AU  - Gaya Wijayaratne
AU  - Jonas Michel Wolf
AU  - Kon Ken Wong
AU  - Qing Ye
AU  - Lay-Myint Yoshida
AU  - Mohammad Tahir Yousafzai
AU  - Anita Zaidi
AU  - Khalequ Zaman
AU  - Heather J Zar
AU  - Qianye Zhao
PY  - 2026
JO  - The Lancet Child & Adolescent Health
DO  - 10.1016/s2352-4642(25)00349-9
UR  - https://doi.org/10.1016/s2352-4642(25)00349-9
ER  - 

APA

Mahmud, S., Zandvoort, K. V., Guo, L., Li, Y., Nair, H., Feikin, D. R., Sparrow, E., Chowdhury, F., Cohen, C., Dbaibo, G. S., Gentile, A., Gill, C. J., Gordon, A., Horton, K. C., Cao, Q., Stolyarov, K., Clark, A. D., Agoti, C. N., Ahumada-Topete, V., Ali, S., Ali, S. A., Al-Iede, M., Al-Shuwaikh, A., Angurana, S. K., Antonio, M., Arif, H., Arruvito, L., Awad, S., Balmaseda, A., Baral, R., Barkat, A., Bar-Zeev, N., Bassat, Q., Bayrakci, B., Becerril-Vargas, E., Bigogo, G., Bimouhen, A., Bodinayake, C., Bont, L., Boutros, C. F., Brizuela, Y. S., Brooks, W. A., Bruminhent, J., C., A. B., Buchwald, A., Bunthi, C., Caballero, M. T., Caini, S., Carlotti, A., Castillo, J. M., Castorena-Maldonado, A. R., Chaiyakunapruk, N., Chandy, S., Chu, H. Y., Danilenko, D., Jesus, J. D., Leon, T. D., Mora, D. D., Mendoza, J. D. V., Deng, J., Domachowske, J., Driscoll, A., Dvorkin, J., Echavarria, M., Eley, B., Escobar, M., Estripeaut, D., Ferrero, F., Flasche, S., Forman, L., Franco, D., Freitas, F. T. D. M., Frivold, C., Furuse, Y., Garba, M. A., Garcia-Corzo, J. R., Garcia-Mauriño, C., Geffner, J., Godinez-Zavala, Y., Gonzalez, R., Goswami, D. R., Gresh, L., Grijalva, C. G., Guiñazú, G., Wakim, R. H., Hassane, F., Hattoufi, K., Hernández-Cárdenas, C. M., Higdon, M., Hindupur, A., Holgado, M. P., Howie, S. R., Hübschen, J. M., Idris, O. O., Giamberardino, H. I. G., Islam, M. A., Islam, M. S., Issa, M., Jara, J., Jara, R., Jiang, W., Juarez, M. D. V., Jullien, S., Kamau, E., Katama, E., Kelly, M. S., Khaing, W., Knoll, M. D., Kockuzu, E., Kolawole, O. M., Komoyo, G. F., Kotloff, K., Koul, P. A., Krishnan, A., Kubale, J., Kumar, R., Kurukulasooriya, R., Lagare, A., Hanchi, A. L., Lanata, C. F., Langley, J. M., Lee, L. Y., Li, S., Liu, W., Liyanage, G., Londono-Avendano, M., Lu, L., Luciani, K., Lucion, M. F., Mackenzie, G., MacLeod, W., Mahmud, M. A., Malasao, R., Manoharan, A., Maree, L., Menon, T., Mokhtari-Azad, T., Morris, S. K., Morrow, B. M., Moyes, J., Mussá, T., Mutunga, M., Mwananyanda, L., Nagahawatte, A., Nasreen, S., Nicol, M. P., Nokes, J., Nosten, F., Noyola, D. E., Nyiro, J., Obodai, E., Okamoto, M., Oladokun, R., Oshitani, H., Otieno, J., Pale, M., Patikorn, C., Pieciak, R., Pisareva, M., Portillo-Vasquez, A. M., Prosperi, C., Raboni, S. M., Rahman, M. Z., Raiden, S., Rave, N., Reyes, N. S., Saha, S. K., Saha, S., Salimi, V., Sananez, I., Sanchez, F., Sande, C., Scott, A., Seetharam, S., Seidenberg, P., Shaaban, F., Simulundu, E., Snoeck, C. J., Sobrinho, F., Sow, S., Srisingh, K., Suryadevara, M., Sutcliffe, C. G., Tan, C. J., Tapia, M., Tavakoli, F., Techasaensiri, C., Thea, D. M., Tillekeratne, L. G., Tligui, H., Turner, P., Vanderburg, S., Vázquez-Pérez, J. A., Vernooij, F., Vieira, S. E., Gottberg, A. V., Wachepa, R., Walaza, S., Watthanaworawit, W., Wijayaratne, G., Wolf, J. M., Wong, K. K., Ye, Q., Yoshida, L., Yousafzai, M. T., Zaidi, A., Zaman, K., Zar, H. J., & Zhao, Q. (2026). Age distribution of respiratory syncytial virus disease in children younger than 5 years in low-income and middle-income countries: a systematic review and meta-analysis. The Lancet Child & Adolescent Health. https://doi.org/10.1016/s2352-4642(25)00349-9

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