Efficacy and safety of 48 weeks of guselkumab for patients with Crohn's disease: maintenance results from the phase 2, randomised, double-blind GALAXI-1 trial

Silvio Danese, Remo Panaccione, Brian G Feagan, Anita Afzali, David T Rubin, Bruce E Sands, Walter Reinisch, Julián Panés, Aparna Sahoo, Natalie A Terry, Daphne Chan, Chenglong Han, Mary Ellen Frustaci, Zijiang Yang, William J Sandborn, Tadakazu Hisamatsu, Jane M Andrews, Geert R D'Haens, Oleksandr Oliinyk, Leonid Bilianskyi, Jadwiga Gniady-Jastrzebska, Robert Petryka, Tomasz Arlukowicz, Piotr Gietka, Marcin Zmudzinski, Syed Mumtaz, Douglas Wolf, Katarzyna Wojcik, George Duvall, Monika Augustyn, Rafal Filip, Dino Tarabar, Alexander Tkachev, Ursula Seidler, Eran Zittan, Juris Pokrotnieks, Oksana Shchukina, Andro Machavariani, Laura Loy, Niazy Abu-farsakh, Pesegova Marina, Slobodan Sreckovic, Martin Laclav, Shu-Chen Wei, Daniel Suiter, Aleksey Borsuk, Xavier Hebuterne, Carsten Buning, Adi Lahat-Zok, Wit Danilkiewicz, Bernadetta Frysna, Ivana Jovicic, Olena Datsenko, Maninder Guram, Animesh Jain, Zahid Rashid, Sonja Heeren, Natallia Shulga, Ivan Timkin, Srdjan Gornjakovic, Milan Lukas, Romain Altwegg, Ariadne Desjeux, Jean-Marie Reimund, Manana Giorgadze, Christoph Jochum, Hiroaki Ito, Katsuhiko Nakai, Tomohisa Takagi, Osamu Zaha, Changhwan Choi, Taeoh Kim, Jonghun Lee, Ieva Stundiene, Ida Normiha Hilmi, Rosaida Hj Md Said, Jaroslaw Leszczyszyn, Diana Abdulganieva, Yulia Fominykh, Svetlana Maksyashina, Jozef Balaz, Manuel Van Domselaar, Taylan Kav, Patrick Dennis, Patricia Henry, Robert Holmes, Christopher Johnson, Matthew McBride, Harry Sarles, Gregory Moore, Ruslan Yakubtsevich, Vinciane Muls, Stevan Trbojevic, Waqqas Afif, Charles Bernstein, Ivo Klarin, Zuzana Serclova, Miroslava Volfova, Pierre Desreumaux, Cyrielle Gilletta de Saint Joseph, Xavier Roblin, Lucine Vuitton, Kakhaber Chelidze, Tanja Kuehbacher, Ioannis Koutroubakis, Michele Cicala, Walter Fries, Antonio Gasbarrini, Nobuo Aoyama, Yoshito Hayashi, Fumihito Hirai, Norkiyuki Horiki, Namiko Hoshi, Tomoki Inaba, Ishida Hiroyasu, Atsuo Maemoto, Takayuki Matsumoto, Kayoko Matsushima, Satoshi Motoya, Masaki Taruishi, Mohammed Rashid, Jaeyoung Chun, Young-Ho Kim, Dong Il Park, Ala Sharara, Laimas Jonaitis, Gjorgi Deriban, James Brooker, Beata Gawdis-Wojnarska, Barbara Wozniak-Stolarska, Pavel Andreev, Vladimir Simanenkov, Vasiliy Trofimov, Igor Jovanovic, Natasa Zdravkovic, Xavier Aldeguer i Mante, Vicent Hernandez Ramirez, Hale Akpinar, Gurkan Celebi, Hulya Hamzaoglu, Juan Fernandez, Jayaprakash Kamath, Nicole Palekar, Jatinder S. Pruthi, David Rausher, Timothy Ritter

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DOI
10.1016/s2468-1253(23)00318-7
Published
2024-02
Container
The Lancet Gastroenterology & Hepatology
Publisher
Elsevier BV
Open access
unknown

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@article{allodium:10.1016/s2468-1253-23-00318-7,
  title = {Efficacy and safety of 48 weeks of guselkumab for patients with Crohn's disease: maintenance results from the phase 2, randomised, double-blind GALAXI-1 trial},
  author = {Silvio Danese and Remo Panaccione and Brian G Feagan and Anita Afzali and David T Rubin and Bruce E Sands and Walter Reinisch and Julián Panés and Aparna Sahoo and Natalie A Terry and Daphne Chan and Chenglong Han and Mary Ellen Frustaci and Zijiang Yang and William J Sandborn and Tadakazu Hisamatsu and Jane M Andrews and Geert R D'Haens and Oleksandr Oliinyk and Leonid Bilianskyi and Jadwiga Gniady-Jastrzebska and Robert Petryka and Tomasz Arlukowicz and Piotr Gietka and Marcin Zmudzinski and Syed Mumtaz and Douglas Wolf and Katarzyna Wojcik and George Duvall and Monika Augustyn and Rafal Filip and Dino Tarabar and Alexander Tkachev and Ursula Seidler and Eran Zittan and Juris Pokrotnieks and Oksana Shchukina and Andro Machavariani and Laura Loy and Niazy Abu-farsakh and Pesegova Marina and Slobodan Sreckovic and Martin Laclav and Shu-Chen Wei and Daniel Suiter and Aleksey Borsuk and Xavier Hebuterne and Carsten Buning and Adi Lahat-Zok and Wit Danilkiewicz and Bernadetta Frysna and Ivana Jovicic and Olena Datsenko and Maninder Guram and Animesh Jain and Zahid Rashid and Sonja Heeren and Natallia Shulga and Ivan Timkin and Srdjan Gornjakovic and Milan Lukas and Romain Altwegg and Ariadne Desjeux and Jean-Marie Reimund and Manana Giorgadze and Christoph Jochum and Hiroaki Ito and Katsuhiko Nakai and Tomohisa Takagi and Osamu Zaha and Changhwan Choi and Taeoh Kim and Jonghun Lee and Ieva Stundiene and Ida Normiha Hilmi and Rosaida Hj Md Said and Jaroslaw Leszczyszyn and Diana Abdulganieva and Yulia Fominykh and Svetlana Maksyashina and Jozef Balaz and Manuel Van Domselaar and Taylan Kav and Patrick Dennis and Patricia Henry and Robert Holmes and Christopher Johnson and Matthew McBride and Harry Sarles and Gregory Moore and Ruslan Yakubtsevich and Vinciane Muls and Stevan Trbojevic and Waqqas Afif and Charles Bernstein and Ivo Klarin and Zuzana Serclova and Miroslava Volfova and Pierre Desreumaux and Cyrielle Gilletta de Saint Joseph and Xavier Roblin and Lucine Vuitton and Kakhaber Chelidze and Tanja Kuehbacher and Ioannis Koutroubakis and Michele Cicala and Walter Fries and Antonio Gasbarrini and Nobuo Aoyama and Yoshito Hayashi and Fumihito Hirai and Norkiyuki Horiki and Namiko Hoshi and Tomoki Inaba and Ishida Hiroyasu and Atsuo Maemoto and Takayuki Matsumoto and Kayoko Matsushima and Satoshi Motoya and Masaki Taruishi and Mohammed Rashid and Jaeyoung Chun and Young-Ho Kim and Dong Il Park and Ala Sharara and Laimas Jonaitis and Gjorgi Deriban and James Brooker and Beata Gawdis-Wojnarska and Barbara Wozniak-Stolarska and Pavel Andreev and Vladimir Simanenkov and Vasiliy Trofimov and Igor Jovanovic and Natasa Zdravkovic and Xavier Aldeguer i Mante and Vicent Hernandez Ramirez and Hale Akpinar and Gurkan Celebi and Hulya Hamzaoglu and Juan Fernandez and Jayaprakash Kamath and Nicole Palekar and Jatinder S. Pruthi and David Rausher and Timothy Ritter},
  year = {2024},
  journal = {The Lancet Gastroenterology \& Hepatology},
  doi = {10.1016/s2468-1253(23)00318-7},
  url = {https://doi.org/10.1016/s2468-1253(23)00318-7}
}

RIS

TY  - JOUR
TI  - Efficacy and safety of 48 weeks of guselkumab for patients with Crohn's disease: maintenance results from the phase 2, randomised, double-blind GALAXI-1 trial
AU  - Silvio Danese
AU  - Remo Panaccione
AU  - Brian G Feagan
AU  - Anita Afzali
AU  - David T Rubin
AU  - Bruce E Sands
AU  - Walter Reinisch
AU  - Julián Panés
AU  - Aparna Sahoo
AU  - Natalie A Terry
AU  - Daphne Chan
AU  - Chenglong Han
AU  - Mary Ellen Frustaci
AU  - Zijiang Yang
AU  - William J Sandborn
AU  - Tadakazu Hisamatsu
AU  - Jane M Andrews
AU  - Geert R D'Haens
AU  - Oleksandr Oliinyk
AU  - Leonid Bilianskyi
AU  - Jadwiga Gniady-Jastrzebska
AU  - Robert Petryka
AU  - Tomasz Arlukowicz
AU  - Piotr Gietka
AU  - Marcin Zmudzinski
AU  - Syed Mumtaz
AU  - Douglas Wolf
AU  - Katarzyna Wojcik
AU  - George Duvall
AU  - Monika Augustyn
AU  - Rafal Filip
AU  - Dino Tarabar
AU  - Alexander Tkachev
AU  - Ursula Seidler
AU  - Eran Zittan
AU  - Juris Pokrotnieks
AU  - Oksana Shchukina
AU  - Andro Machavariani
AU  - Laura Loy
AU  - Niazy Abu-farsakh
AU  - Pesegova Marina
AU  - Slobodan Sreckovic
AU  - Martin Laclav
AU  - Shu-Chen Wei
AU  - Daniel Suiter
AU  - Aleksey Borsuk
AU  - Xavier Hebuterne
AU  - Carsten Buning
AU  - Adi Lahat-Zok
AU  - Wit Danilkiewicz
AU  - Bernadetta Frysna
AU  - Ivana Jovicic
AU  - Olena Datsenko
AU  - Maninder Guram
AU  - Animesh Jain
AU  - Zahid Rashid
AU  - Sonja Heeren
AU  - Natallia Shulga
AU  - Ivan Timkin
AU  - Srdjan Gornjakovic
AU  - Milan Lukas
AU  - Romain Altwegg
AU  - Ariadne Desjeux
AU  - Jean-Marie Reimund
AU  - Manana Giorgadze
AU  - Christoph Jochum
AU  - Hiroaki Ito
AU  - Katsuhiko Nakai
AU  - Tomohisa Takagi
AU  - Osamu Zaha
AU  - Changhwan Choi
AU  - Taeoh Kim
AU  - Jonghun Lee
AU  - Ieva Stundiene
AU  - Ida Normiha Hilmi
AU  - Rosaida Hj Md Said
AU  - Jaroslaw Leszczyszyn
AU  - Diana Abdulganieva
AU  - Yulia Fominykh
AU  - Svetlana Maksyashina
AU  - Jozef Balaz
AU  - Manuel Van Domselaar
AU  - Taylan Kav
AU  - Patrick Dennis
AU  - Patricia Henry
AU  - Robert Holmes
AU  - Christopher Johnson
AU  - Matthew McBride
AU  - Harry Sarles
AU  - Gregory Moore
AU  - Ruslan Yakubtsevich
AU  - Vinciane Muls
AU  - Stevan Trbojevic
AU  - Waqqas Afif
AU  - Charles Bernstein
AU  - Ivo Klarin
AU  - Zuzana Serclova
AU  - Miroslava Volfova
AU  - Pierre Desreumaux
AU  - Cyrielle Gilletta de Saint Joseph
AU  - Xavier Roblin
AU  - Lucine Vuitton
AU  - Kakhaber Chelidze
AU  - Tanja Kuehbacher
AU  - Ioannis Koutroubakis
AU  - Michele Cicala
AU  - Walter Fries
AU  - Antonio Gasbarrini
AU  - Nobuo Aoyama
AU  - Yoshito Hayashi
AU  - Fumihito Hirai
AU  - Norkiyuki Horiki
AU  - Namiko Hoshi
AU  - Tomoki Inaba
AU  - Ishida Hiroyasu
AU  - Atsuo Maemoto
AU  - Takayuki Matsumoto
AU  - Kayoko Matsushima
AU  - Satoshi Motoya
AU  - Masaki Taruishi
AU  - Mohammed Rashid
AU  - Jaeyoung Chun
AU  - Young-Ho Kim
AU  - Dong Il Park
AU  - Ala Sharara
AU  - Laimas Jonaitis
AU  - Gjorgi Deriban
AU  - James Brooker
AU  - Beata Gawdis-Wojnarska
AU  - Barbara Wozniak-Stolarska
AU  - Pavel Andreev
AU  - Vladimir Simanenkov
AU  - Vasiliy Trofimov
AU  - Igor Jovanovic
AU  - Natasa Zdravkovic
AU  - Xavier Aldeguer i Mante
AU  - Vicent Hernandez Ramirez
AU  - Hale Akpinar
AU  - Gurkan Celebi
AU  - Hulya Hamzaoglu
AU  - Juan Fernandez
AU  - Jayaprakash Kamath
AU  - Nicole Palekar
AU  - Jatinder S. Pruthi
AU  - David Rausher
AU  - Timothy Ritter
PY  - 2024
JO  - The Lancet Gastroenterology & Hepatology
DO  - 10.1016/s2468-1253(23)00318-7
UR  - https://doi.org/10.1016/s2468-1253(23)00318-7
ER  -

APA

Danese, S., Panaccione, R., Feagan, B. G., Afzali, A., Rubin, D. T., Sands, B. E., Reinisch, W., Panés, J., Sahoo, A., Terry, N. A., Chan, D., Han, C., Frustaci, M. E., Yang, Z., Sandborn, W. J., Hisamatsu, T., Andrews, J. M., D'Haens, G. R., Oliinyk, O., Bilianskyi, L., Gniady-Jastrzebska, J., Petryka, R., Arlukowicz, T., Gietka, P., Zmudzinski, M., Mumtaz, S., Wolf, D., Wojcik, K., Duvall, G., Augustyn, M., Filip, R., Tarabar, D., Tkachev, A., Seidler, U., Zittan, E., Pokrotnieks, J., Shchukina, O., Machavariani, A., Loy, L., Abu-farsakh, N., Marina, P., Sreckovic, S., Laclav, M., Wei, S., Suiter, D., Borsuk, A., Hebuterne, X., Buning, C., Lahat-Zok, A., Danilkiewicz, W., Frysna, B., Jovicic, I., Datsenko, O., Guram, M., Jain, A., Rashid, Z., Heeren, S., Shulga, N., Timkin, I., Gornjakovic, S., Lukas, M., Altwegg, R., Desjeux, A., Reimund, J., Giorgadze, M., Jochum, C., Ito, H., Nakai, K., Takagi, T., Zaha, O., Choi, C., Kim, T., Lee, J., Stundiene, I., Hilmi, I. N., Said, R. H. M., Leszczyszyn, J., Abdulganieva, D., Fominykh, Y., Maksyashina, S., Balaz, J., Domselaar, M. V., Kav, T., Dennis, P., Henry, P., Holmes, R., Johnson, C., McBride, M., Sarles, H., Moore, G., Yakubtsevich, R., Muls, V., Trbojevic, S., Afif, W., Bernstein, C., Klarin, I., Serclova, Z., Volfova, M., Desreumaux, P., Joseph, C. G. D. S., Roblin, X., Vuitton, L., Chelidze, K., Kuehbacher, T., Koutroubakis, I., Cicala, M., Fries, W., Gasbarrini, A., Aoyama, N., Hayashi, Y., Hirai, F., Horiki, N., Hoshi, N., Inaba, T., Hiroyasu, I., Maemoto, A., Matsumoto, T., Matsushima, K., Motoya, S., Taruishi, M., Rashid, M., Chun, J., Kim, Y., Park, D. I., Sharara, A., Jonaitis, L., Deriban, G., Brooker, J., Gawdis-Wojnarska, B., Wozniak-Stolarska, B., Andreev, P., Simanenkov, V., Trofimov, V., Jovanovic, I., Zdravkovic, N., Mante, X. A. I., Ramirez, V. H., Akpinar, H., Celebi, G., Hamzaoglu, H., Fernandez, J., Kamath, J., Palekar, N., Pruthi, J. S., Rausher, D., & Ritter, T. (2024). Efficacy and safety of 48 weeks of guselkumab for patients with Crohn's disease: maintenance results from the phase 2, randomised, double-blind GALAXI-1 trial. The Lancet Gastroenterology & Hepatology. https://doi.org/10.1016/s2468-1253(23)00318-7

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