The small interfering RNA imdusiran as single and multiple doses in healthy, randomised individuals and non-randomised individuals with chronic hepatitis B (AB-729-001): a phase 1a/b trial.

Yuen MF, Gane E, Holmes JA, Strasser SI, Leerapun A, Sukeepaisarnjaroen W, Tangkijvanich P, Berliba E, Jucov A, Kim YJ, Lim YS, Thi EP, Eley T, Gray KR, Medvedeva E, Sharma V, Espiritu C, Ganchua SC, Paratala BS, Iott C, Sevinsky H, Fortney T, Anderson M, Cloherty GA, Sofia MJ, Pamulapati GR, Lee ACH, Picchio G, Sims KD

Open source

DOI
10.1016/s2468-1253(26)00058-0
Published
2026 Jul
Container
The lancet. Gastroenterology & hepatology
Publisher
Not recorded
Open access
unknown

Credibility signals

limited evidence Score 43/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

Cite this work

BibTeX

@article{allodium:10.1016/s2468-1253-26-00058-0,
  title = {The small interfering RNA imdusiran as single and multiple doses in healthy, randomised individuals and non-randomised individuals with chronic hepatitis B (AB-729-001): a phase 1a/b trial.},
  author = {Yuen MF and Gane E and Holmes JA and Strasser SI and Leerapun A and Sukeepaisarnjaroen W and Tangkijvanich P and Berliba E and Jucov A and Kim YJ and Lim YS and Thi EP and Eley T and Gray KR and Medvedeva E and Sharma V and Espiritu C and Ganchua SC and Paratala BS and Iott C and Sevinsky H and Fortney T and Anderson M and Cloherty GA and Sofia MJ and Pamulapati GR and Lee ACH and Picchio G and Sims KD},
  year = {2026},
  journal = {The lancet. Gastroenterology \& hepatology},
  doi = {10.1016/s2468-1253(26)00058-0},
  url = {https://doi.org/10.1016/s2468-1253(26)00058-0}
}

RIS

TY  - JOUR
TI  - The small interfering RNA imdusiran as single and multiple doses in healthy, randomised individuals and non-randomised individuals with chronic hepatitis B (AB-729-001): a phase 1a/b trial.
AU  - Yuen MF
AU  - Gane E
AU  - Holmes JA
AU  - Strasser SI
AU  - Leerapun A
AU  - Sukeepaisarnjaroen W
AU  - Tangkijvanich P
AU  - Berliba E
AU  - Jucov A
AU  - Kim YJ
AU  - Lim YS
AU  - Thi EP
AU  - Eley T
AU  - Gray KR
AU  - Medvedeva E
AU  - Sharma V
AU  - Espiritu C
AU  - Ganchua SC
AU  - Paratala BS
AU  - Iott C
AU  - Sevinsky H
AU  - Fortney T
AU  - Anderson M
AU  - Cloherty GA
AU  - Sofia MJ
AU  - Pamulapati GR
AU  - Lee ACH
AU  - Picchio G
AU  - Sims KD
PY  - 2026
JO  - The lancet. Gastroenterology & hepatology
DO  - 10.1016/s2468-1253(26)00058-0
UR  - https://doi.org/10.1016/s2468-1253(26)00058-0
ER  - 

APA

MF, Y., E, G., JA, H., SI, S., A, L., W, S., P, T., E, B., A, J., YJ, K., YS, L., EP, T., T, E., KR, G., E, M., V, S., C, E., SC, G., BS, P., C, I., H, S., T, F., M, A., GA, C., MJ, S., GR, P., ACH, L., G, P., & KD, S. (2026). The small interfering RNA imdusiran as single and multiple doses in healthy, randomised individuals and non-randomised individuals with chronic hepatitis B (AB-729-001): a phase 1a/b trial.. The lancet. Gastroenterology & hepatology. https://doi.org/10.1016/s2468-1253(26)00058-0

Source records