Aspirin for cancer prevention in individuals with Lynch syndrome: first results from the CaPP3 multicentre, randomised, double-blind, non-inferiority trial

John Burn, Gillian M Borthwick, Faye Elliott, Finlay Macrae, Kai Ren Ong, Alison C Kraus, Nadir Arber, Jukka-Pekka Mecklin, Angel Alonso, Emma R Woodward, D Gareth Evans, Alex Murray, Katie Snape, Ruth E Cleaver, Adam Shaw, Huw J W Thomas, Ajith V Kumar, Dorothy Halliday, Lucy E Side, Rachel E Harrison, Rosemarie Davidson, Ruth Armstrong, Jackie Cook, Rachel Hart, Patrick J Morrison, Julian G Barwell, Alan Donaldson, Zoe Kemp, Jennie Murray, Zosia Miedzybrodzka, Caroline Pottinger, Jonathan Berg, Richard Gallon, D Timothy Bishop, Naim Abu-Freha, Alex Boussioutas, Diana M Eccles, Lynn Greenhalgh, Ana Guerra Lacunza, Elizabeth E Half, Helen Hanson, Rachel Hart, Christine M Hayes, Donna Job, Zafirah Khan, Anjana Kulkarni, Zohar Levi, Lynne Longstaff, Helen Mar Fan, John C Mathers, Victoria Murday, Mary EM Porteous, Kirsi Pylvänäinen, Lynn Reed, Dimitra Repana, Toni T Seppala, Shiran Shapira, Allan Spigelman, Helene Thygesen, James Toh, Kathy Wu

Open source

DOI
10.1016/s2468-1253(26)00114-7
Published
2026-09
Container
The Lancet Gastroenterology & Hepatology
Publisher
Elsevier BV
Open access
unknown

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BibTeX

@article{allodium:10.1016/s2468-1253-26-00114-7,
  title = {Aspirin for cancer prevention in individuals with Lynch syndrome: first results from the CaPP3 multicentre, randomised, double-blind, non-inferiority trial},
  author = {John Burn and Gillian M Borthwick and Faye Elliott and Finlay Macrae and Kai Ren Ong and Alison C Kraus and Nadir Arber and Jukka-Pekka Mecklin and Angel Alonso and Emma R Woodward and D Gareth Evans and Alex Murray and Katie Snape and Ruth E Cleaver and Adam Shaw and Huw J W Thomas and Ajith V Kumar and Dorothy Halliday and Lucy E Side and Rachel E Harrison and Rosemarie Davidson and Ruth Armstrong and Jackie Cook and Rachel Hart and Patrick J Morrison and Julian G Barwell and Alan Donaldson and Zoe Kemp and Jennie Murray and Zosia Miedzybrodzka and Caroline Pottinger and Jonathan Berg and Richard Gallon and D Timothy Bishop and Naim Abu-Freha and Alex Boussioutas and Diana M Eccles and Lynn Greenhalgh and Ana Guerra Lacunza and Elizabeth E Half and Helen Hanson and Rachel Hart and Christine M Hayes and Donna Job and Zafirah Khan and Anjana Kulkarni and Zohar Levi and Lynne Longstaff and Helen Mar Fan and John C Mathers and Victoria Murday and Mary EM Porteous and Kirsi Pylvänäinen and Lynn Reed and Dimitra Repana and Toni T Seppala and Shiran Shapira and Allan Spigelman and Helene Thygesen and James Toh and Kathy Wu},
  year = {2026},
  journal = {The Lancet Gastroenterology \& Hepatology},
  doi = {10.1016/s2468-1253(26)00114-7},
  url = {https://doi.org/10.1016/s2468-1253(26)00114-7}
}

RIS

TY  - JOUR
TI  - Aspirin for cancer prevention in individuals with Lynch syndrome: first results from the CaPP3 multicentre, randomised, double-blind, non-inferiority trial
AU  - John Burn
AU  - Gillian M Borthwick
AU  - Faye Elliott
AU  - Finlay Macrae
AU  - Kai Ren Ong
AU  - Alison C Kraus
AU  - Nadir Arber
AU  - Jukka-Pekka Mecklin
AU  - Angel Alonso
AU  - Emma R Woodward
AU  - D Gareth Evans
AU  - Alex Murray
AU  - Katie Snape
AU  - Ruth E Cleaver
AU  - Adam Shaw
AU  - Huw J W Thomas
AU  - Ajith V Kumar
AU  - Dorothy Halliday
AU  - Lucy E Side
AU  - Rachel E Harrison
AU  - Rosemarie Davidson
AU  - Ruth Armstrong
AU  - Jackie Cook
AU  - Rachel Hart
AU  - Patrick J Morrison
AU  - Julian G Barwell
AU  - Alan Donaldson
AU  - Zoe Kemp
AU  - Jennie Murray
AU  - Zosia Miedzybrodzka
AU  - Caroline Pottinger
AU  - Jonathan Berg
AU  - Richard Gallon
AU  - D Timothy Bishop
AU  - Naim Abu-Freha
AU  - Alex Boussioutas
AU  - Diana M Eccles
AU  - Lynn Greenhalgh
AU  - Ana Guerra Lacunza
AU  - Elizabeth E Half
AU  - Helen Hanson
AU  - Rachel Hart
AU  - Christine M Hayes
AU  - Donna Job
AU  - Zafirah Khan
AU  - Anjana Kulkarni
AU  - Zohar Levi
AU  - Lynne Longstaff
AU  - Helen Mar Fan
AU  - John C Mathers
AU  - Victoria Murday
AU  - Mary EM Porteous
AU  - Kirsi Pylvänäinen
AU  - Lynn Reed
AU  - Dimitra Repana
AU  - Toni T Seppala
AU  - Shiran Shapira
AU  - Allan Spigelman
AU  - Helene Thygesen
AU  - James Toh
AU  - Kathy Wu
PY  - 2026
JO  - The Lancet Gastroenterology & Hepatology
DO  - 10.1016/s2468-1253(26)00114-7
UR  - https://doi.org/10.1016/s2468-1253(26)00114-7
ER  - 

APA

Burn, J., Borthwick, G. M., Elliott, F., Macrae, F., Ong, K. R., Kraus, A. C., Arber, N., Mecklin, J., Alonso, A., Woodward, E. R., Evans, D. G., Murray, A., Snape, K., Cleaver, R. E., Shaw, A., Thomas, H. J. W., Kumar, A. V., Halliday, D., Side, L. E., Harrison, R. E., Davidson, R., Armstrong, R., Cook, J., Hart, R., Morrison, P. J., Barwell, J. G., Donaldson, A., Kemp, Z., Murray, J., Miedzybrodzka, Z., Pottinger, C., Berg, J., Gallon, R., Bishop, D. T., Abu-Freha, N., Boussioutas, A., Eccles, D. M., Greenhalgh, L., Lacunza, A. G., Half, E. E., Hanson, H., Hart, R., Hayes, C. M., Job, D., Khan, Z., Kulkarni, A., Levi, Z., Longstaff, L., Fan, H. M., Mathers, J. C., Murday, V., Porteous, M. E., Pylvänäinen, K., Reed, L., Repana, D., Seppala, T. T., Shapira, S., Spigelman, A., Thygesen, H., Toh, J., & Wu, K. (2026). Aspirin for cancer prevention in individuals with Lynch syndrome: first results from the CaPP3 multicentre, randomised, double-blind, non-inferiority trial. The Lancet Gastroenterology & Hepatology. https://doi.org/10.1016/s2468-1253(26)00114-7

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