Sweet Protein Allosteric Binding and Activation of the Human T1R2/R3 Sweet Receptor: A Simulation Model Validated by in Vitro Receptor Activation Assay

Phillip Vo, Daniel E. Connors, Brendan P. Sharkey, Stephen A. Gravina, Guy Servant, Chase T. McFarland, Tyler T. Pitkanen, Christopher D. Burk, Chloe P. Cowen, Elizabeth M. Grein, Sara M. Henderson, James P. Langan, Leonard T. Rael, Ryan J. Totman, Anthony Clark, Zheyuan Guo, Ashley Han, Joseph Meilen, Marina Nadal, Anthony Westgate, Mark E. Williams, Lan Zhang, Ranjan Patnaik

Open source

DOI: 10.1021/acs.biochem.5c00622
Published: 2026-01-27
Container: Biochemistry
Publisher: American Chemical Society (ACS)
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1021/acs.biochem.5c00622,
  title = {Sweet Protein Allosteric Binding and Activation of the Human T1R2/R3 Sweet Receptor: A Simulation Model Validated by in Vitro Receptor Activation Assay},
  author = {Phillip Vo and Daniel E. Connors and Brendan P. Sharkey and Stephen A. Gravina and Guy Servant and Chase T. McFarland and Tyler T. Pitkanen and Christopher D. Burk and Chloe P. Cowen and Elizabeth M. Grein and Sara M. Henderson and James P. Langan and Leonard T. Rael and Ryan J. Totman and Anthony Clark and Zheyuan Guo and Ashley Han and Joseph Meilen and Marina Nadal and Anthony Westgate and Mark E. Williams and Lan Zhang and Ranjan Patnaik},
  year = {2026},
  journal = {Biochemistry},
  doi = {10.1021/acs.biochem.5c00622},
  url = {https://doi.org/10.1021/acs.biochem.5c00622}
}

RIS

TY  - JOUR
TI  - Sweet Protein Allosteric Binding and Activation of the Human T1R2/R3 Sweet Receptor: A Simulation Model Validated by in Vitro Receptor Activation Assay
AU  - Phillip Vo
AU  - Daniel E. Connors
AU  - Brendan P. Sharkey
AU  - Stephen A. Gravina
AU  - Guy Servant
AU  - Chase T. McFarland
AU  - Tyler T. Pitkanen
AU  - Christopher D. Burk
AU  - Chloe P. Cowen
AU  - Elizabeth M. Grein
AU  - Sara M. Henderson
AU  - James P. Langan
AU  - Leonard T. Rael
AU  - Ryan J. Totman
AU  - Anthony Clark
AU  - Zheyuan Guo
AU  - Ashley Han
AU  - Joseph Meilen
AU  - Marina Nadal
AU  - Anthony Westgate
AU  - Mark E. Williams
AU  - Lan Zhang
AU  - Ranjan Patnaik
PY  - 2026
JO  - Biochemistry
DO  - 10.1021/acs.biochem.5c00622
UR  - https://doi.org/10.1021/acs.biochem.5c00622
ER  -

APA

Vo, P., Connors, D. E., Sharkey, B. P., Gravina, S. A., Servant, G., McFarland, C. T., Pitkanen, T. T., Burk, C. D., Cowen, C. P., Grein, E. M., Henderson, S. M., Langan, J. P., Rael, L. T., Totman, R. J., Clark, A., Guo, Z., Han, A., Meilen, J., Nadal, M., Westgate, A., Williams, M. E., Zhang, L., & Patnaik, R. (2026). Sweet Protein Allosteric Binding and Activation of the Human T1R2/R3 Sweet Receptor: A Simulation Model Validated by in Vitro Receptor Activation Assay. Biochemistry. https://doi.org/10.1021/acs.biochem.5c00622

Source records

crossref · retrieved 2026-09-25T11:30:23.789Z