Discovery and Validation of the Binding Poses of Allosteric Fragment Hits to Protein Tyrosine Phosphatase 1b: From Molecular Dynamics Simulations to X-ray Crystallography

Jack B. Greisman, Lindsay Willmore, Christine Y. Yeh, Fabrizio Giordanetto, Sahar Shahamadtar, Hunter Nisonoff, Paul Maragakis, David E. Shaw

Open source

DOI
10.1021/acs.jcim.3c00236
Published
2023-04-22
Container
Journal of Chemical Information and Modeling
Publisher
American Chemical Society (ACS)
Open access
unknown

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BibTeX

@article{allodium:10.1021/acs.jcim.3c00236,
  title = {Discovery and Validation of the Binding Poses of Allosteric Fragment Hits to Protein Tyrosine Phosphatase 1b: From Molecular Dynamics Simulations to X-ray Crystallography},
  author = {Jack B. Greisman and Lindsay Willmore and Christine Y. Yeh and Fabrizio Giordanetto and Sahar Shahamadtar and Hunter Nisonoff and Paul Maragakis and David E. Shaw},
  year = {2023},
  journal = {Journal of Chemical Information and Modeling},
  doi = {10.1021/acs.jcim.3c00236},
  url = {https://doi.org/10.1021/acs.jcim.3c00236}
}

RIS

TY  - JOUR
TI  - Discovery and Validation of the Binding Poses of Allosteric Fragment Hits to Protein Tyrosine Phosphatase 1b: From Molecular Dynamics Simulations to X-ray Crystallography
AU  - Jack B. Greisman
AU  - Lindsay Willmore
AU  - Christine Y. Yeh
AU  - Fabrizio Giordanetto
AU  - Sahar Shahamadtar
AU  - Hunter Nisonoff
AU  - Paul Maragakis
AU  - David E. Shaw
PY  - 2023
JO  - Journal of Chemical Information and Modeling
DO  - 10.1021/acs.jcim.3c00236
UR  - https://doi.org/10.1021/acs.jcim.3c00236
ER  - 

APA

Greisman, J. B., Willmore, L., Yeh, C. Y., Giordanetto, F., Shahamadtar, S., Nisonoff, H., Maragakis, P., & Shaw, D. E. (2023). Discovery and Validation of the Binding Poses of Allosteric Fragment Hits to Protein Tyrosine Phosphatase 1b: From Molecular Dynamics Simulations to X-ray Crystallography. Journal of Chemical Information and Modeling. https://doi.org/10.1021/acs.jcim.3c00236

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