Multiparameter Optimization of Broad-Spectrum Antibacterial Activity, ADMET Properties, and MAO-A/B Inhibition of Novel Biaryloxazolidinone-Hydrazone Derivatives: Identification of a Lead with In Vivo Efficacy against Linezolid-Resistant Staphylococcus aureus.

Duan M, Huang X, Qiu C, Sun L, He X, Wang Z, Yue H, Peng S, Shi X, Wang H, Tong M, Ding X, Hou Y, Zhao Y

DOI: 10.1021/acs.jmedchem.5c00037
Published: 2025 Aug 28
Container: Journal of medicinal chemistry
Publisher: Not recorded
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1021/acs.jmedchem.5c00037,
  title = {Multiparameter Optimization of Broad-Spectrum Antibacterial Activity, ADMET Properties, and MAO-A/B Inhibition of Novel Biaryloxazolidinone-Hydrazone Derivatives: Identification of a Lead with In Vivo Efficacy against Linezolid-Resistant Staphylococcus aureus.},
  author = {Duan M and Huang X and Qiu C and Sun L and He X and Wang Z and Yue H and Peng S and Shi X and Wang H and Tong M and Ding X and Hou Y and Zhao Y},
  year = {2025},
  journal = {Journal of medicinal chemistry},
  doi = {10.1021/acs.jmedchem.5c00037},
  url = {https://doi.org/10.1021/acs.jmedchem.5c00037}
}

RIS

TY  - JOUR
TI  - Multiparameter Optimization of Broad-Spectrum Antibacterial Activity, ADMET Properties, and MAO-A/B Inhibition of Novel Biaryloxazolidinone-Hydrazone Derivatives: Identification of a Lead with In Vivo Efficacy against Linezolid-Resistant Staphylococcus aureus.
AU  - Duan M
AU  - Huang X
AU  - Qiu C
AU  - Sun L
AU  - He X
AU  - Wang Z
AU  - Yue H
AU  - Peng S
AU  - Shi X
AU  - Wang H
AU  - Tong M
AU  - Ding X
AU  - Hou Y
AU  - Zhao Y
PY  - 2025
JO  - Journal of medicinal chemistry
DO  - 10.1021/acs.jmedchem.5c00037
UR  - https://doi.org/10.1021/acs.jmedchem.5c00037
ER  -

APA

M, D., X, H., C, Q., L, S., X, H., Z, W., H, Y., S, P., X, S., H, W., M, T., X, D., Y, H., & Y, Z. (2025). Multiparameter Optimization of Broad-Spectrum Antibacterial Activity, ADMET Properties, and MAO-A/B Inhibition of Novel Biaryloxazolidinone-Hydrazone Derivatives: Identification of a Lead with In Vivo Efficacy against Linezolid-Resistant Staphylococcus aureus.. Journal of medicinal chemistry. https://doi.org/10.1021/acs.jmedchem.5c00037

Source records

pubmed · retrieved 2026-09-27T16:00:55.446Z