Enhancing Solubility in VHL-Based PROTACs: Optimized USP7 Degraders for Improved Developability.

Wittenburg S, Zuleeg MR, Peter K, Lemnitzer P, Voget R, Bricelj A, Gobec M, Dierlamm N, Braun MB, Geiger TM, Heim C, Stakemeier A, Wagner KG, Nowak RP, Hartmann MD, Sosič I, Gütschow M, Krönke J, Steinebach C

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DOI: 10.1021/acs.jmedchem.5c00718
Published: 2025 Aug 14
Container: Journal of medicinal chemistry
Publisher: Not recorded
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1021/acs.jmedchem.5c00718,
  title = {Enhancing Solubility in VHL-Based PROTACs: Optimized USP7 Degraders for Improved Developability.},
  author = {Wittenburg S and Zuleeg MR and Peter K and Lemnitzer P and Voget R and Bricelj A and Gobec M and Dierlamm N and Braun MB and Geiger TM and Heim C and Stakemeier A and Wagner KG and Nowak RP and Hartmann MD and Sosič I and Gütschow M and Krönke J and Steinebach C},
  year = {2025},
  journal = {Journal of medicinal chemistry},
  doi = {10.1021/acs.jmedchem.5c00718},
  url = {https://doi.org/10.1021/acs.jmedchem.5c00718}
}

RIS

TY  - JOUR
TI  - Enhancing Solubility in VHL-Based PROTACs: Optimized USP7 Degraders for Improved Developability.
AU  - Wittenburg S
AU  - Zuleeg MR
AU  - Peter K
AU  - Lemnitzer P
AU  - Voget R
AU  - Bricelj A
AU  - Gobec M
AU  - Dierlamm N
AU  - Braun MB
AU  - Geiger TM
AU  - Heim C
AU  - Stakemeier A
AU  - Wagner KG
AU  - Nowak RP
AU  - Hartmann MD
AU  - Sosič I
AU  - Gütschow M
AU  - Krönke J
AU  - Steinebach C
PY  - 2025
JO  - Journal of medicinal chemistry
DO  - 10.1021/acs.jmedchem.5c00718
UR  - https://doi.org/10.1021/acs.jmedchem.5c00718
ER  -

APA

S, W., MR, Z., K, P., P, L., R, V., A, B., M, G., N, D., MB, B., TM, G., C, H., A, S., KG, W., RP, N., MD, H., I, S., M, G., J, K., & C, S. (2025). Enhancing Solubility in VHL-Based PROTACs: Optimized USP7 Degraders for Improved Developability.. Journal of medicinal chemistry. https://doi.org/10.1021/acs.jmedchem.5c00718

Source records

pubmed · retrieved 2026-09-26T02:17:27.016Z