Design, Synthesis, and Biological Evaluation of Arylimidazole Derivatives as Potent PPARδ Agonists for the Treatment of Renal Fibrosis

Zhiqi Feng, Junkai Xie, Dongliang Hou, Zhuoxin Fu, Suyang Sun, Xinpeng Liu, Gang Sun, Runan Zheng, Liu Liu, Qinglong Xu, Xiaoan Wen, Daoxu Zhang, Haoliang Yuan, Hongbin Sun, Liang Dai

Open source

DOI
10.1021/acs.jmedchem.5c03132
Published
2026-02-10
Container
Journal of Medicinal Chemistry
Publisher
American Chemical Society (ACS)
Open access
unknown

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BibTeX

@article{allodium:10.1021/acs.jmedchem.5c03132,
  title = {Design, Synthesis, and Biological Evaluation of Arylimidazole Derivatives as Potent PPARδ Agonists for the Treatment of Renal Fibrosis},
  author = {Zhiqi Feng and Junkai Xie and Dongliang Hou and Zhuoxin Fu and Suyang Sun and Xinpeng Liu and Gang Sun and Runan Zheng and Liu Liu and Qinglong Xu and Xiaoan Wen and Daoxu Zhang and Haoliang Yuan and Hongbin Sun and Liang Dai},
  year = {2026},
  journal = {Journal of Medicinal Chemistry},
  doi = {10.1021/acs.jmedchem.5c03132},
  url = {https://doi.org/10.1021/acs.jmedchem.5c03132}
}

RIS

TY  - JOUR
TI  - Design, Synthesis, and Biological Evaluation of Arylimidazole Derivatives as Potent PPARδ Agonists for the Treatment of Renal Fibrosis
AU  - Zhiqi Feng
AU  - Junkai Xie
AU  - Dongliang Hou
AU  - Zhuoxin Fu
AU  - Suyang Sun
AU  - Xinpeng Liu
AU  - Gang Sun
AU  - Runan Zheng
AU  - Liu Liu
AU  - Qinglong Xu
AU  - Xiaoan Wen
AU  - Daoxu Zhang
AU  - Haoliang Yuan
AU  - Hongbin Sun
AU  - Liang Dai
PY  - 2026
JO  - Journal of Medicinal Chemistry
DO  - 10.1021/acs.jmedchem.5c03132
UR  - https://doi.org/10.1021/acs.jmedchem.5c03132
ER  - 

APA

Feng, Z., Xie, J., Hou, D., Fu, Z., Sun, S., Liu, X., Sun, G., Zheng, R., Liu, L., Xu, Q., Wen, X., Zhang, D., Yuan, H., Sun, H., & Dai, L. (2026). Design, Synthesis, and Biological Evaluation of Arylimidazole Derivatives as Potent PPARδ Agonists for the Treatment of Renal Fibrosis. Journal of Medicinal Chemistry. https://doi.org/10.1021/acs.jmedchem.5c03132

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