Rational Design of Small-Molecule Stabilizers of Human Fumarylacetoacetate Hydrolase for the Treatment of Tyrosinemia Type I

Riccardo Scarin, Adriana L. Rojas, Jon Gil-Martínez, Margarita Gómez-Galán, Ángel Torres-Mozas, Fernando Lopitz-Otsoa, David Fernández-Ramos, Gonzalo Jiménez-Osés, José M. Mato, Oscar Millet

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DOI: 10.1021/acs.jmedchem.5c03489
Published: 2026-05-12
Container: Journal of Medicinal Chemistry
Publisher: American Chemical Society (ACS)
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1021/acs.jmedchem.5c03489,
  title = {Rational Design of Small-Molecule Stabilizers of Human Fumarylacetoacetate Hydrolase for the Treatment of Tyrosinemia Type I},
  author = {Riccardo Scarin and Adriana L. Rojas and Jon Gil-Martínez and Margarita Gómez-Galán and Ángel Torres-Mozas and Fernando Lopitz-Otsoa and David Fernández-Ramos and Gonzalo Jiménez-Osés and José M. Mato and Oscar Millet},
  year = {2026},
  journal = {Journal of Medicinal Chemistry},
  doi = {10.1021/acs.jmedchem.5c03489},
  url = {https://doi.org/10.1021/acs.jmedchem.5c03489}
}

RIS

TY  - JOUR
TI  - Rational Design of Small-Molecule Stabilizers of Human Fumarylacetoacetate Hydrolase for the Treatment of Tyrosinemia Type I
AU  - Riccardo Scarin
AU  - Adriana L. Rojas
AU  - Jon Gil-Martínez
AU  - Margarita Gómez-Galán
AU  - Ángel Torres-Mozas
AU  - Fernando Lopitz-Otsoa
AU  - David Fernández-Ramos
AU  - Gonzalo Jiménez-Osés
AU  - José M. Mato
AU  - Oscar Millet
PY  - 2026
JO  - Journal of Medicinal Chemistry
DO  - 10.1021/acs.jmedchem.5c03489
UR  - https://doi.org/10.1021/acs.jmedchem.5c03489
ER  -

APA

Scarin, R., Rojas, A. L., Gil-Martínez, J., Gómez-Galán, M., Torres-Mozas, Á., Lopitz-Otsoa, F., Fernández-Ramos, D., Jiménez-Osés, G., Mato, J. M., & Millet, O. (2026). Rational Design of Small-Molecule Stabilizers of Human Fumarylacetoacetate Hydrolase for the Treatment of Tyrosinemia Type I. Journal of Medicinal Chemistry. https://doi.org/10.1021/acs.jmedchem.5c03489

Source records

crossref · retrieved 2026-09-26T02:44:23.472Z