Optimization and Characterization of SHIP1 Ligands for Cellular Target Engagement and Activity in Alzheimer’s Disease Models

Cynthia D. Jesudason, Claudia Rangel-Barajas, Colin J. Beach, Daniel E. Beck, Isaac H. Caballero-Floran, W. Brent Clayton, Lais Da Silva, Juliane C. David, Suzanne Doolen, Alexandra N. Faulkner, Adam K. Hamdani, Hasi Huhe, Kevin Huynh, Ryan D. Imhoff, June Javens-Wolfe, Emily R. Mason, Mustapha Moussaif, Kratika Singhal, Disha M. Soni, Matilda van Buuren-Milne, Sean-Paul Williams, Steven P. Angus, Shaoyou Chu, Jeffrey L. Dage, Philip A. Hipskind, Travis S. Johnson, Rima Kaddurah-Daouk, Bruce T. Lamb, Peter J. Meikle, Andrew D. Mesecar, Alan D. Palkowitz, Sara K. Quinney, Stacey J. Sukoff Rizzo, Adrian L. Oblak, Timothy I. Richardson

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DOI: 10.1021/acs.jmedchem.6c00010
Published: 2026-04-30
Container: Journal of Medicinal Chemistry
Publisher: American Chemical Society (ACS)
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1021/acs.jmedchem.6c00010,
  title = {Optimization and Characterization of SHIP1 Ligands for Cellular Target Engagement and Activity in Alzheimer’s Disease Models},
  author = {Cynthia D. Jesudason and Claudia Rangel-Barajas and Colin J. Beach and Daniel E. Beck and Isaac H. Caballero-Floran and W. Brent Clayton and Lais Da Silva and Juliane C. David and Suzanne Doolen and Alexandra N. Faulkner and Adam K. Hamdani and Hasi Huhe and Kevin Huynh and Ryan D. Imhoff and June Javens-Wolfe and Emily R. Mason and Mustapha Moussaif and Kratika Singhal and Disha M. Soni and Matilda van Buuren-Milne and Sean-Paul Williams and Steven P. Angus and Shaoyou Chu and Jeffrey L. Dage and Philip A. Hipskind and Travis S. Johnson and Rima Kaddurah-Daouk and Bruce T. Lamb and Peter J. Meikle and Andrew D. Mesecar and Alan D. Palkowitz and Sara K. Quinney and Stacey J. Sukoff Rizzo and Adrian L. Oblak and Timothy I. Richardson},
  year = {2026},
  journal = {Journal of Medicinal Chemistry},
  doi = {10.1021/acs.jmedchem.6c00010},
  url = {https://doi.org/10.1021/acs.jmedchem.6c00010}
}

RIS

TY  - JOUR
TI  - Optimization and Characterization of SHIP1 Ligands for Cellular Target Engagement and Activity in Alzheimer’s Disease Models
AU  - Cynthia D. Jesudason
AU  - Claudia Rangel-Barajas
AU  - Colin J. Beach
AU  - Daniel E. Beck
AU  - Isaac H. Caballero-Floran
AU  - W. Brent Clayton
AU  - Lais Da Silva
AU  - Juliane C. David
AU  - Suzanne Doolen
AU  - Alexandra N. Faulkner
AU  - Adam K. Hamdani
AU  - Hasi Huhe
AU  - Kevin Huynh
AU  - Ryan D. Imhoff
AU  - June Javens-Wolfe
AU  - Emily R. Mason
AU  - Mustapha Moussaif
AU  - Kratika Singhal
AU  - Disha M. Soni
AU  - Matilda van Buuren-Milne
AU  - Sean-Paul Williams
AU  - Steven P. Angus
AU  - Shaoyou Chu
AU  - Jeffrey L. Dage
AU  - Philip A. Hipskind
AU  - Travis S. Johnson
AU  - Rima Kaddurah-Daouk
AU  - Bruce T. Lamb
AU  - Peter J. Meikle
AU  - Andrew D. Mesecar
AU  - Alan D. Palkowitz
AU  - Sara K. Quinney
AU  - Stacey J. Sukoff Rizzo
AU  - Adrian L. Oblak
AU  - Timothy I. Richardson
PY  - 2026
JO  - Journal of Medicinal Chemistry
DO  - 10.1021/acs.jmedchem.6c00010
UR  - https://doi.org/10.1021/acs.jmedchem.6c00010
ER  -

APA

Jesudason, C. D., Rangel-Barajas, C., Beach, C. J., Beck, D. E., Caballero-Floran, I. H., Clayton, W. B., Silva, L. D., David, J. C., Doolen, S., Faulkner, A. N., Hamdani, A. K., Huhe, H., Huynh, K., Imhoff, R. D., Javens-Wolfe, J., Mason, E. R., Moussaif, M., Singhal, K., Soni, D. M., Buuren-Milne, M. V., Williams, S., Angus, S. P., Chu, S., Dage, J. L., Hipskind, P. A., Johnson, T. S., Kaddurah-Daouk, R., Lamb, B. T., Meikle, P. J., Mesecar, A. D., Palkowitz, A. D., Quinney, S. K., Rizzo, S. J. S., Oblak, A. L., & Richardson, T. I. (2026). Optimization and Characterization of SHIP1 Ligands for Cellular Target Engagement and Activity in Alzheimer’s Disease Models. Journal of Medicinal Chemistry. https://doi.org/10.1021/acs.jmedchem.6c00010

Source records

crossref · retrieved 2026-09-26T11:02:27.907Z