The Discovery of TNG456: A Highly Potent, Selective, Brain-Penetrant MTA-Cooperative PRMT5 Inhibitor for the Treatment of <i>MTAP</i> -Deleted Cancers
- DOI
- 10.1021/acs.jmedchem.6c00035
- Published
- 2026-05-18
- Container
- Journal of Medicinal Chemistry
- Publisher
- American Chemical Society (ACS)
- Open access
- unknown
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Cite this work
BibTeX
@article{allodium:10.1021/acs.jmedchem.6c00035,
title = {The Discovery of
TNG456: A Highly Potent, Selective,
Brain-Penetrant MTA-Cooperative PRMT5 Inhibitor for the Treatment
of
<i>MTAP</i>
-Deleted Cancers},
author = {Kevin M. Cottrell and Kimberly J. Briggs and Alice Tsai and Colin Liang and Patrick McCarren and Douglas A. Whittington and Minjie Zhang and Wenhai Zhang and Alan Huang and Jannik Andersen and John P. Maxwell},
year = {2026},
journal = {Journal of Medicinal Chemistry},
doi = {10.1021/acs.jmedchem.6c00035},
url = {https://doi.org/10.1021/acs.jmedchem.6c00035}
}RIS
TY - JOUR
TI - The Discovery of
TNG456: A Highly Potent, Selective,
Brain-Penetrant MTA-Cooperative PRMT5 Inhibitor for the Treatment
of
<i>MTAP</i>
-Deleted Cancers
AU - Kevin M. Cottrell
AU - Kimberly J. Briggs
AU - Alice Tsai
AU - Colin Liang
AU - Patrick McCarren
AU - Douglas A. Whittington
AU - Minjie Zhang
AU - Wenhai Zhang
AU - Alan Huang
AU - Jannik Andersen
AU - John P. Maxwell
PY - 2026
JO - Journal of Medicinal Chemistry
DO - 10.1021/acs.jmedchem.6c00035
UR - https://doi.org/10.1021/acs.jmedchem.6c00035
ER - APA
Cottrell, K. M., Briggs, K. J., Tsai, A., Liang, C., McCarren, P., Whittington, D. A., Zhang, M., Zhang, W., Huang, A., Andersen, J., & Maxwell, J. P. (2026). The Discovery of TNG456: A Highly Potent, Selective, Brain-Penetrant MTA-Cooperative PRMT5 Inhibitor for the Treatment of <i>MTAP</i> -Deleted Cancers. Journal of Medicinal Chemistry. https://doi.org/10.1021/acs.jmedchem.6c00035
Source records
- crossref · retrieved 2026-09-26T05:34:26.312Z