Structure-Guided Discovery of OAT-4828 as Potent, Selective, and Orally Bioavailable USP7 Inhibitor with In Vivo Antileukemic Activity.

Chrzanowski J, Nowicka J, Koralewski R, Joachimiak L, Gzik A, Borek B, Brzezinska J, Kusmirek D, Olejniczak S, Matyszewski K, Mazur M, Olczak J, Glatt S, Grudnik P, Wilk P, Muchowicz A, Kikulska A, Gluchowska KM, Drzewicka K, Belczyk-Ciesielska A, Wachowska M, Sipak-Bujanowicz Z, Mulewski K, Tkaczyk A, Rejczak T, Golebiowski A, Zaslona Z, Blaszczyk R

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DOI: 10.1021/acs.jmedchem.6c00407
Published: 2026 May 28
Container: Journal of medicinal chemistry
Publisher: Not recorded
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1021/acs.jmedchem.6c00407,
  title = {Structure-Guided Discovery of OAT-4828 as Potent, Selective, and Orally Bioavailable USP7 Inhibitor with In Vivo Antileukemic Activity.},
  author = {Chrzanowski J and Nowicka J and Koralewski R and Joachimiak L and Gzik A and Borek B and Brzezinska J and Kusmirek D and Olejniczak S and Matyszewski K and Mazur M and Olczak J and Glatt S and Grudnik P and Wilk P and Muchowicz A and Kikulska A and Gluchowska KM and Drzewicka K and Belczyk-Ciesielska A and Wachowska M and Sipak-Bujanowicz Z and Mulewski K and Tkaczyk A and Rejczak T and Golebiowski A and Zaslona Z and Blaszczyk R},
  year = {2026},
  journal = {Journal of medicinal chemistry},
  doi = {10.1021/acs.jmedchem.6c00407},
  url = {https://doi.org/10.1021/acs.jmedchem.6c00407}
}

RIS

TY  - JOUR
TI  - Structure-Guided Discovery of OAT-4828 as Potent, Selective, and Orally Bioavailable USP7 Inhibitor with In Vivo Antileukemic Activity.
AU  - Chrzanowski J
AU  - Nowicka J
AU  - Koralewski R
AU  - Joachimiak L
AU  - Gzik A
AU  - Borek B
AU  - Brzezinska J
AU  - Kusmirek D
AU  - Olejniczak S
AU  - Matyszewski K
AU  - Mazur M
AU  - Olczak J
AU  - Glatt S
AU  - Grudnik P
AU  - Wilk P
AU  - Muchowicz A
AU  - Kikulska A
AU  - Gluchowska KM
AU  - Drzewicka K
AU  - Belczyk-Ciesielska A
AU  - Wachowska M
AU  - Sipak-Bujanowicz Z
AU  - Mulewski K
AU  - Tkaczyk A
AU  - Rejczak T
AU  - Golebiowski A
AU  - Zaslona Z
AU  - Blaszczyk R
PY  - 2026
JO  - Journal of medicinal chemistry
DO  - 10.1021/acs.jmedchem.6c00407
UR  - https://doi.org/10.1021/acs.jmedchem.6c00407
ER  -

APA

J, C., J, N., R, K., L, J., A, G., B, B., J, B., D, K., S, O., K, M., M, M., J, O., S, G., P, G., P, W., A, M., A, K., KM, G., K, D., A, B., M, W., Z, S., K, M., A, T., T, R., A, G., Z, Z., & R, B. (2026). Structure-Guided Discovery of OAT-4828 as Potent, Selective, and Orally Bioavailable USP7 Inhibitor with In Vivo Antileukemic Activity.. Journal of medicinal chemistry. https://doi.org/10.1021/acs.jmedchem.6c00407

Source records

pubmed · retrieved 2026-09-26T15:58:52.416Z