Structure-Based Drug Design of Novel Indazole/Indolinone-Based Biaryl Derivatives as Oral IRAK4 Inhibitors for the Treatment of Inflammatory Diseases

Zhenwei Zhang, Xue Wang, Xuan Luo, Cong Li, Zesheng Liu, Chunmei Xia, Leyi Yu, Xiaowei Chen, Yaqian Sun, Peipei Wang, Lixin Gao, Xinyue Cao, Yufei Zhang, Yibing Wang, Hong Liu, Yili Sun, Shengbin Zhou, Jia Li, Yu Zhou

Open source

DOI
10.1021/acs.jmedchem.6c00667
Published
2026-07-28
Container
Journal of Medicinal Chemistry
Publisher
American Chemical Society (ACS)
Open access
unknown

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Cite this work

BibTeX

@article{allodium:10.1021/acs.jmedchem.6c00667,
  title = {Structure-Based
Drug Design of Novel Indazole/Indolinone-Based
Biaryl Derivatives as Oral IRAK4 Inhibitors for the Treatment of Inflammatory
Diseases},
  author = {Zhenwei Zhang and Xue Wang and Xuan Luo and Cong Li and Zesheng Liu and Chunmei Xia and Leyi Yu and Xiaowei Chen and Yaqian Sun and Peipei Wang and Lixin Gao and Xinyue Cao and Yufei Zhang and Yibing Wang and Hong Liu and Yili Sun and Shengbin Zhou and Jia Li and Yu Zhou},
  year = {2026},
  journal = {Journal of Medicinal Chemistry},
  doi = {10.1021/acs.jmedchem.6c00667},
  url = {https://doi.org/10.1021/acs.jmedchem.6c00667}
}

RIS

TY  - JOUR
TI  - Structure-Based
Drug Design of Novel Indazole/Indolinone-Based
Biaryl Derivatives as Oral IRAK4 Inhibitors for the Treatment of Inflammatory
Diseases
AU  - Zhenwei Zhang
AU  - Xue Wang
AU  - Xuan Luo
AU  - Cong Li
AU  - Zesheng Liu
AU  - Chunmei Xia
AU  - Leyi Yu
AU  - Xiaowei Chen
AU  - Yaqian Sun
AU  - Peipei Wang
AU  - Lixin Gao
AU  - Xinyue Cao
AU  - Yufei Zhang
AU  - Yibing Wang
AU  - Hong Liu
AU  - Yili Sun
AU  - Shengbin Zhou
AU  - Jia Li
AU  - Yu Zhou
PY  - 2026
JO  - Journal of Medicinal Chemistry
DO  - 10.1021/acs.jmedchem.6c00667
UR  - https://doi.org/10.1021/acs.jmedchem.6c00667
ER  - 

APA

Zhang, Z., Wang, X., Luo, X., Li, C., Liu, Z., Xia, C., Yu, L., Chen, X., Sun, Y., Wang, P., Gao, L., Cao, X., Zhang, Y., Wang, Y., Liu, H., Sun, Y., Zhou, S., Li, J., & Zhou, Y. (2026). Structure-Based Drug Design of Novel Indazole/Indolinone-Based Biaryl Derivatives as Oral IRAK4 Inhibitors for the Treatment of Inflammatory Diseases. Journal of Medicinal Chemistry. https://doi.org/10.1021/acs.jmedchem.6c00667

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