In Vivo Efficacy and Biochemical Target Engagement of a Chromene-Based Inhibitor of Trypanosoma cruzi Lysyl-tRNA Synthetase.

Dos Santos TCF, de Lima Silva CC, Eufrásio AG, Tambascia C, De Sousa IL, Marchese L, Catelli MF, de Almeida LR, Costa Venancio GD, de Souza VB, Schenka AA, Rocco SA, Mercaldi GF, Cordeiro AT

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DOI: 10.1021/acs.jmedchem.6c00764
Published: 2026 Sep 10
Container: Journal of medicinal chemistry
Publisher: Not recorded
Open access: yes

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Cite this work

BibTeX

@article{allodium:10.1021/acs.jmedchem.6c00764,
  title = {In Vivo Efficacy and Biochemical Target Engagement of a Chromene-Based Inhibitor of Trypanosoma cruzi Lysyl-tRNA Synthetase.},
  author = {Dos Santos TCF and de Lima Silva CC and Eufrásio AG and Tambascia C and De Sousa IL and Marchese L and Catelli MF and de Almeida LR and Costa Venancio GD and de Souza VB and Schenka AA and Rocco SA and Mercaldi GF and Cordeiro AT},
  year = {2026},
  journal = {Journal of medicinal chemistry},
  doi = {10.1021/acs.jmedchem.6c00764},
  url = {https://doi.org/10.1021/acs.jmedchem.6c00764}
}

RIS

TY  - JOUR
TI  - In Vivo Efficacy and Biochemical Target Engagement of a Chromene-Based Inhibitor of Trypanosoma cruzi Lysyl-tRNA Synthetase.
AU  - Dos Santos TCF
AU  - de Lima Silva CC
AU  - Eufrásio AG
AU  - Tambascia C
AU  - De Sousa IL
AU  - Marchese L
AU  - Catelli MF
AU  - de Almeida LR
AU  - Costa Venancio GD
AU  - de Souza VB
AU  - Schenka AA
AU  - Rocco SA
AU  - Mercaldi GF
AU  - Cordeiro AT
PY  - 2026
JO  - Journal of medicinal chemistry
DO  - 10.1021/acs.jmedchem.6c00764
UR  - https://doi.org/10.1021/acs.jmedchem.6c00764
ER  -

APA

TCF, D. S., CC, D. L. S., AG, E., C, T., IL, D. S., L, M., MF, C., LR, D. A., GD, C. V., VB, D. S., AA, S., SA, R., GF, M., & AT, C. (2026). In Vivo Efficacy and Biochemical Target Engagement of a Chromene-Based Inhibitor of Trypanosoma cruzi Lysyl-tRNA Synthetase.. Journal of medicinal chemistry. https://doi.org/10.1021/acs.jmedchem.6c00764

Source records

pubmed · retrieved 2026-09-26T15:59:00.131Z