Design, Synthesis, and Antitumor Activity Evaluation of Novel Dual A2A/A2B Adenosine Receptor Antagonists

Michał Gałęzowski, Maciej Kujawa, Aneta Bobowska, Matylda Stefaniak-Szałas, Joanna Szeremeta-Spisak, Marcin Nowogródzki, Grzegorz Ćwiertnia, Paulina Niedziejko-Ćwiertnia, Adam Radzimierski, Karolina Gluza, Karolina Grycuk, Katarzyna Dziedzic, Paulina Węgrzyn, Stefan Chmielewski, Grzegorz Satała, Ewelina Gabor-Worwa, Sanja Novak Ratajczak, Aniela Gołas, Maciej K. Rogacki, Mateusz Nowak, Krzysztof Brzózka

Open source

DOI: 10.1021/acs.jmedchem.6c00868
Published: 2026-08-24
Container: Journal of Medicinal Chemistry
Publisher: American Chemical Society (ACS)
Open access: unknown

Credibility signals

uncertain Score 64/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

supportingDOI registered: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
supportingDOI resolves: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredOpen access status: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
supportingMetadata completeness: All 6 scored descriptive metadata groups are present. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1021/acs.jmedchem.6c00868,
  title = {Design, Synthesis,
and Antitumor Activity Evaluation
of Novel Dual A2A/A2B Adenosine Receptor Antagonists},
  author = {Michał Gałęzowski and Maciej Kujawa and Aneta Bobowska and Matylda Stefaniak-Szałas and Joanna Szeremeta-Spisak and Marcin Nowogródzki and Grzegorz Ćwiertnia and Paulina Niedziejko-Ćwiertnia and Adam Radzimierski and Karolina Gluza and Karolina Grycuk and Katarzyna Dziedzic and Paulina Węgrzyn and Stefan Chmielewski and Grzegorz Satała and Ewelina Gabor-Worwa and Sanja Novak Ratajczak and Aniela Gołas and Maciej K. Rogacki and Mateusz Nowak and Krzysztof Brzózka},
  year = {2026},
  journal = {Journal of Medicinal Chemistry},
  doi = {10.1021/acs.jmedchem.6c00868},
  url = {https://doi.org/10.1021/acs.jmedchem.6c00868}
}

RIS

TY  - JOUR
TI  - Design, Synthesis,
and Antitumor Activity Evaluation
of Novel Dual A2A/A2B Adenosine Receptor Antagonists
AU  - Michał Gałęzowski
AU  - Maciej Kujawa
AU  - Aneta Bobowska
AU  - Matylda Stefaniak-Szałas
AU  - Joanna Szeremeta-Spisak
AU  - Marcin Nowogródzki
AU  - Grzegorz Ćwiertnia
AU  - Paulina Niedziejko-Ćwiertnia
AU  - Adam Radzimierski
AU  - Karolina Gluza
AU  - Karolina Grycuk
AU  - Katarzyna Dziedzic
AU  - Paulina Węgrzyn
AU  - Stefan Chmielewski
AU  - Grzegorz Satała
AU  - Ewelina Gabor-Worwa
AU  - Sanja Novak Ratajczak
AU  - Aniela Gołas
AU  - Maciej K. Rogacki
AU  - Mateusz Nowak
AU  - Krzysztof Brzózka
PY  - 2026
JO  - Journal of Medicinal Chemistry
DO  - 10.1021/acs.jmedchem.6c00868
UR  - https://doi.org/10.1021/acs.jmedchem.6c00868
ER  -

APA

Gałęzowski, M., Kujawa, M., Bobowska, A., Stefaniak-Szałas, M., Szeremeta-Spisak, J., Nowogródzki, M., Ćwiertnia, G., Niedziejko-Ćwiertnia, P., Radzimierski, A., Gluza, K., Grycuk, K., Dziedzic, K., Węgrzyn, P., Chmielewski, S., Satała, G., Gabor-Worwa, E., Ratajczak, S. N., Gołas, A., Rogacki, M. K., Nowak, M., & Brzózka, K. (2026). Design, Synthesis, and Antitumor Activity Evaluation of Novel Dual A2A/A2B Adenosine Receptor Antagonists. Journal of Medicinal Chemistry. https://doi.org/10.1021/acs.jmedchem.6c00868

Source records

crossref · retrieved 2026-09-27T10:03:43.797Z