Discovery of a Covalent NLRP3 LRR-Domain Probe: Reversing Renal Fibrosis via Immunometabolic Reprogramming in Organoid and Murine Models.

Wu WH, Yao Y, Liu K, Ma ZY, Wei LY, Li YX, Niu KM, Cai J, Qi XY, Chen HK, Xiao W, Zhang XW, Sun YY, Ma GX, Zhang L, Chen ZZ, Jiang C, Gu ZZ, Qi LW, Xu LL

Open source

DOI: 10.1021/acs.jmedchem.6c01482
Published: 2026 Sep 10
Container: Journal of medicinal chemistry
Publisher: Not recorded
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1021/acs.jmedchem.6c01482,
  title = {Discovery of a Covalent NLRP3 LRR-Domain Probe: Reversing Renal Fibrosis via Immunometabolic Reprogramming in Organoid and Murine Models.},
  author = {Wu WH and Yao Y and Liu K and Ma ZY and Wei LY and Li YX and Niu KM and Cai J and Qi XY and Chen HK and Xiao W and Zhang XW and Sun YY and Ma GX and Zhang L and Chen ZZ and Jiang C and Gu ZZ and Qi LW and Xu LL},
  year = {2026},
  journal = {Journal of medicinal chemistry},
  doi = {10.1021/acs.jmedchem.6c01482},
  url = {https://doi.org/10.1021/acs.jmedchem.6c01482}
}

RIS

TY  - JOUR
TI  - Discovery of a Covalent NLRP3 LRR-Domain Probe: Reversing Renal Fibrosis via Immunometabolic Reprogramming in Organoid and Murine Models.
AU  - Wu WH
AU  - Yao Y
AU  - Liu K
AU  - Ma ZY
AU  - Wei LY
AU  - Li YX
AU  - Niu KM
AU  - Cai J
AU  - Qi XY
AU  - Chen HK
AU  - Xiao W
AU  - Zhang XW
AU  - Sun YY
AU  - Ma GX
AU  - Zhang L
AU  - Chen ZZ
AU  - Jiang C
AU  - Gu ZZ
AU  - Qi LW
AU  - Xu LL
PY  - 2026
JO  - Journal of medicinal chemistry
DO  - 10.1021/acs.jmedchem.6c01482
UR  - https://doi.org/10.1021/acs.jmedchem.6c01482
ER  -

APA

WH, W., Y, Y., K, L., ZY, M., LY, W., YX, L., KM, N., J, C., XY, Q., HK, C., W, X., XW, Z., YY, S., GX, M., L, Z., ZZ, C., C, J., ZZ, G., LW, Q., & LL, X. (2026). Discovery of a Covalent NLRP3 LRR-Domain Probe: Reversing Renal Fibrosis via Immunometabolic Reprogramming in Organoid and Murine Models.. Journal of medicinal chemistry. https://doi.org/10.1021/acs.jmedchem.6c01482

Source records

pubmed · retrieved 2026-09-27T08:37:49.579Z