Discovery of a Quinazoline-Based Nav1.7 Inhibitor with MicroED-Confirmed Absolute Configuration and Oral Efficacy in Rodent Models of Neuropathic Pain

Jae Ho Shim, Pooreum Lim, Sangwoo Woo, Jihye Han, Hyeon Soo Kim

Open source

DOI
10.1021/acs.jmedchem.6c02422
Published
2026-09-30
Container
Journal of Medicinal Chemistry
Publisher
American Chemical Society (ACS)
Open access
unknown

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BibTeX

@article{allodium:10.1021/acs.jmedchem.6c02422,
  title = {Discovery of a Quinazoline-Based Nav1.7 Inhibitor with MicroED-Confirmed Absolute Configuration and Oral Efficacy in Rodent Models of Neuropathic Pain},
  author = {Jae Ho Shim and Pooreum Lim and Sangwoo Woo and Jihye Han and Hyeon Soo Kim},
  year = {2026},
  journal = {Journal of Medicinal Chemistry},
  doi = {10.1021/acs.jmedchem.6c02422},
  url = {https://doi.org/10.1021/acs.jmedchem.6c02422}
}

RIS

TY  - JOUR
TI  - Discovery of a Quinazoline-Based Nav1.7 Inhibitor with MicroED-Confirmed Absolute Configuration and Oral Efficacy in Rodent Models of Neuropathic Pain
AU  - Jae Ho Shim
AU  - Pooreum Lim
AU  - Sangwoo Woo
AU  - Jihye Han
AU  - Hyeon Soo Kim
PY  - 2026
JO  - Journal of Medicinal Chemistry
DO  - 10.1021/acs.jmedchem.6c02422
UR  - https://doi.org/10.1021/acs.jmedchem.6c02422
ER  - 

APA

Shim, J. H., Lim, P., Woo, S., Han, J., & Kim, H. S. (2026). Discovery of a Quinazoline-Based Nav1.7 Inhibitor with MicroED-Confirmed Absolute Configuration and Oral Efficacy in Rodent Models of Neuropathic Pain. Journal of Medicinal Chemistry. https://doi.org/10.1021/acs.jmedchem.6c02422

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