Trifluoromethylthio and Trifluoromethyl Functionalization of Endomorphin-1 Enhances its Hydrophobicity and Plasma Stability while Preserving its Affinity for the μ-Opioid Receptor.
- DOI
- 10.1021/acs.joc.6c00321
- Published
- 2026 Apr 24
- Container
- The Journal of organic chemistry
- Publisher
- Not recorded
- Open access
- yes
Credibility signals
limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.
Show all credibility signals
- cautionDOI registered: No matching Crossref record was present in this response.
- cautionDOI resolves: No matching Crossref record was present in this response.
- not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility.
- not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made.
- not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made.
- not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made.
- not scoredROR affiliation: Not checked or no result supplied; no credibility inference made.
- not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete.
- not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete.
- not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete.
- not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete.
- supportingOpen access status: Normalized open-access status: open.
- not scoredPublication license: Not checked or no result supplied; no credibility inference made.
- not scoredPublication version: A publication version was supplied but is not scored.
- cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty.
Cite this work
BibTeX
@article{allodium:10.1021/acs.joc.6c00321,
title = {Trifluoromethylthio and Trifluoromethyl Functionalization of Endomorphin-1 Enhances its Hydrophobicity and Plasma Stability while Preserving its Affinity for the μ-Opioid Receptor.},
author = {Gregorc J and De Neve J and Guitot K and Holleran BJ and Lensen N and Gendron L and Brigaud T and Iskra J and Ballet S and Chaume G},
year = {2026},
journal = {The Journal of organic chemistry},
doi = {10.1021/acs.joc.6c00321},
url = {https://doi.org/10.1021/acs.joc.6c00321}
}RIS
TY - JOUR TI - Trifluoromethylthio and Trifluoromethyl Functionalization of Endomorphin-1 Enhances its Hydrophobicity and Plasma Stability while Preserving its Affinity for the μ-Opioid Receptor. AU - Gregorc J AU - De Neve J AU - Guitot K AU - Holleran BJ AU - Lensen N AU - Gendron L AU - Brigaud T AU - Iskra J AU - Ballet S AU - Chaume G PY - 2026 JO - The Journal of organic chemistry DO - 10.1021/acs.joc.6c00321 UR - https://doi.org/10.1021/acs.joc.6c00321 ER -
APA
J, G., J, D. N., K, G., BJ, H., N, L., L, G., T, B., J, I., S, B., & G, C. (2026). Trifluoromethylthio and Trifluoromethyl Functionalization of Endomorphin-1 Enhances its Hydrophobicity and Plasma Stability while Preserving its Affinity for the μ-Opioid Receptor.. The Journal of organic chemistry. https://doi.org/10.1021/acs.joc.6c00321
Source records
- pubmed · retrieved 2026-09-26T17:12:18.466Z