Directed Evolution of Artificial Enzyme with a Catalytic Noncanonical Amino Acid for Asymmetric Friedel–Crafts Alkylation of Cyclic Enones with Indoles

Yuhui Sheng, Beibei Lin, Ya Wei, Shiping Wang, Xiang Sheng, Zhi Zhou

Open source

DOI: 10.1021/acs.orglett.6c03958
Published: 2026-10-29
Container: Organic Letters
Publisher: American Chemical Society (ACS)
Open access: unknown

Credibility signals

uncertain Score 64/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

supportingDOI registered: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
supportingDOI resolves: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredOpen access status: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
supportingMetadata completeness: All 6 scored descriptive metadata groups are present. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1021/acs.orglett.6c03958,
  title = {Directed Evolution of Artificial Enzyme with a Catalytic
Noncanonical Amino Acid for Asymmetric Friedel–Crafts Alkylation
of Cyclic Enones with Indoles},
  author = {Yuhui Sheng and Beibei Lin and Ya Wei and Shiping Wang and Xiang Sheng and Zhi Zhou},
  year = {2026},
  journal = {Organic Letters},
  doi = {10.1021/acs.orglett.6c03958},
  url = {https://doi.org/10.1021/acs.orglett.6c03958}
}

RIS

TY  - JOUR
TI  - Directed Evolution of Artificial Enzyme with a Catalytic
Noncanonical Amino Acid for Asymmetric Friedel–Crafts Alkylation
of Cyclic Enones with Indoles
AU  - Yuhui Sheng
AU  - Beibei Lin
AU  - Ya Wei
AU  - Shiping Wang
AU  - Xiang Sheng
AU  - Zhi Zhou
PY  - 2026
JO  - Organic Letters
DO  - 10.1021/acs.orglett.6c03958
UR  - https://doi.org/10.1021/acs.orglett.6c03958
ER  -

APA

Sheng, Y., Lin, B., Wei, Y., Wang, S., Sheng, X., & Zhou, Z. (2026). Directed Evolution of Artificial Enzyme with a Catalytic Noncanonical Amino Acid for Asymmetric Friedel–Crafts Alkylation of Cyclic Enones with Indoles. Organic Letters. https://doi.org/10.1021/acs.orglett.6c03958

Source records

crossref · retrieved 2026-11-08T23:18:44.598Z