Discovery and Preclinical Evaluations of Potent, Selective, and Allosteric Covalent WRN Inhibitors with Improved PK Properties.

Xu Z, Xiao Q, Liu Y, Jiang W, Liu L, Sun H, Yang X, Lu Z, Yan B, Long H, Zhang X

Open source

DOI
10.1021/acsmedchemlett.5c00787
Published
2026 Feb 12
Container
ACS medicinal chemistry letters
Publisher
Not recorded
Open access
yes

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BibTeX

@article{allodium:10.1021/acsmedchemlett.5c00787,
  title = {Discovery and Preclinical Evaluations of Potent, Selective, and Allosteric Covalent WRN Inhibitors with Improved PK Properties.},
  author = {Xu Z and Xiao Q and Liu Y and Jiang W and Liu L and Sun H and Yang X and Lu Z and Yan B and Long H and Zhang X},
  year = {2026},
  journal = {ACS medicinal chemistry letters},
  doi = {10.1021/acsmedchemlett.5c00787},
  url = {https://doi.org/10.1021/acsmedchemlett.5c00787}
}

RIS

TY  - JOUR
TI  - Discovery and Preclinical Evaluations of Potent, Selective, and Allosteric Covalent WRN Inhibitors with Improved PK Properties.
AU  - Xu Z
AU  - Xiao Q
AU  - Liu Y
AU  - Jiang W
AU  - Liu L
AU  - Sun H
AU  - Yang X
AU  - Lu Z
AU  - Yan B
AU  - Long H
AU  - Zhang X
PY  - 2026
JO  - ACS medicinal chemistry letters
DO  - 10.1021/acsmedchemlett.5c00787
UR  - https://doi.org/10.1021/acsmedchemlett.5c00787
ER  - 

APA

Z, X., Q, X., Y, L., W, J., L, L., H, S., X, Y., Z, L., B, Y., H, L., & X, Z. (2026). Discovery and Preclinical Evaluations of Potent, Selective, and Allosteric Covalent WRN Inhibitors with Improved PK Properties.. ACS medicinal chemistry letters. https://doi.org/10.1021/acsmedchemlett.5c00787

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