Nitrile-Based Inhibitors Targeting both SARS-CoV-2 Main Protease and Human Cathepsin L

Leonard Barasa, Yongzhi Chen, Ala M. Shaqra, Syeda F. Z. Adnan, Lauren E. Intravaia, Sandeep Huchaiah, Akumalla Allabaji, Karthik Kumar S, Srinivasa Rao Vidadala, Santoshkumar N. Patil, Jeffrey Hale, Celia A. Schiffer, Katherine A. Fitzgerald, Paul R. Thompson

Open source

DOI
10.1021/acsmedchemlett.6c00236
Published
2026-08-29
Container
ACS Medicinal Chemistry Letters
Publisher
American Chemical Society (ACS)
Open access
unknown

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BibTeX

@article{allodium:10.1021/acsmedchemlett.6c00236,
  title = {Nitrile-Based
Inhibitors Targeting both SARS-CoV-2
Main Protease and Human Cathepsin L},
  author = {Leonard Barasa and Yongzhi Chen and Ala M. Shaqra and Syeda F. Z. Adnan and Lauren E. Intravaia and Sandeep Huchaiah and Akumalla Allabaji and Karthik Kumar S and Srinivasa Rao Vidadala and Santoshkumar N. Patil and Jeffrey Hale and Celia A. Schiffer and Katherine A. Fitzgerald and Paul R. Thompson},
  year = {2026},
  journal = {ACS Medicinal Chemistry
Letters},
  doi = {10.1021/acsmedchemlett.6c00236},
  url = {https://doi.org/10.1021/acsmedchemlett.6c00236}
}

RIS

TY  - JOUR
TI  - Nitrile-Based
Inhibitors Targeting both SARS-CoV-2
Main Protease and Human Cathepsin L
AU  - Leonard Barasa
AU  - Yongzhi Chen
AU  - Ala M. Shaqra
AU  - Syeda F. Z. Adnan
AU  - Lauren E. Intravaia
AU  - Sandeep Huchaiah
AU  - Akumalla Allabaji
AU  - Karthik Kumar S
AU  - Srinivasa Rao Vidadala
AU  - Santoshkumar N. Patil
AU  - Jeffrey Hale
AU  - Celia A. Schiffer
AU  - Katherine A. Fitzgerald
AU  - Paul R. Thompson
PY  - 2026
JO  - ACS Medicinal Chemistry
Letters
DO  - 10.1021/acsmedchemlett.6c00236
UR  - https://doi.org/10.1021/acsmedchemlett.6c00236
ER  - 

APA

Barasa, L., Chen, Y., Shaqra, A. M., Adnan, S. F. Z., Intravaia, L. E., Huchaiah, S., Allabaji, A., S, K. K., Vidadala, S. R., Patil, S. N., Hale, J., Schiffer, C. A., Fitzgerald, K. A., & Thompson, P. R. (2026). Nitrile-Based Inhibitors Targeting both SARS-CoV-2 Main Protease and Human Cathepsin L. ACS Medicinal Chemistry Letters. https://doi.org/10.1021/acsmedchemlett.6c00236

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