Site-Specific Glycan Conjugation Improves Stability and Efficacy of an Antibody–Drug Conjugates Bearing DXd as a Cytotoxic Payload

Shino Manabe, Shogo Senga, Shogo Iwamoto, Hikaru Yarita, Ryo Takahashi, Ai Mitani, Wataru Sumiyoshi, Asako Hoshinoo, Methanee Hiranyakorn, Takashi Kinoshita, Chihoko Yoshimura

Open source

DOI: 10.1021/acsomega.5c10898
Published: 2026-02-16
Container: ACS Omega
Publisher: American Chemical Society (ACS)
Open access: unknown

Credibility signals

uncertain Score 64/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

supportingDOI registered: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
supportingDOI resolves: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredOpen access status: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
supportingMetadata completeness: All 6 scored descriptive metadata groups are present. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1021/acsomega.5c10898,
  title = {Site-Specific Glycan Conjugation Improves Stability and Efficacy of an Antibody–Drug Conjugates Bearing DXd as a Cytotoxic Payload},
  author = {Shino Manabe and Shogo Senga and Shogo Iwamoto and Hikaru Yarita and Ryo Takahashi and Ai Mitani and Wataru Sumiyoshi and Asako Hoshinoo and Methanee Hiranyakorn and Takashi Kinoshita and Chihoko Yoshimura},
  year = {2026},
  journal = {ACS Omega},
  doi = {10.1021/acsomega.5c10898},
  url = {https://doi.org/10.1021/acsomega.5c10898}
}

RIS

TY  - JOUR
TI  - Site-Specific Glycan Conjugation Improves Stability and Efficacy of an Antibody–Drug Conjugates Bearing DXd as a Cytotoxic Payload
AU  - Shino Manabe
AU  - Shogo Senga
AU  - Shogo Iwamoto
AU  - Hikaru Yarita
AU  - Ryo Takahashi
AU  - Ai Mitani
AU  - Wataru Sumiyoshi
AU  - Asako Hoshinoo
AU  - Methanee Hiranyakorn
AU  - Takashi Kinoshita
AU  - Chihoko Yoshimura
PY  - 2026
JO  - ACS Omega
DO  - 10.1021/acsomega.5c10898
UR  - https://doi.org/10.1021/acsomega.5c10898
ER  -

APA

Manabe, S., Senga, S., Iwamoto, S., Yarita, H., Takahashi, R., Mitani, A., Sumiyoshi, W., Hoshinoo, A., Hiranyakorn, M., Kinoshita, T., & Yoshimura, C. (2026). Site-Specific Glycan Conjugation Improves Stability and Efficacy of an Antibody–Drug Conjugates Bearing DXd as a Cytotoxic Payload. ACS Omega. https://doi.org/10.1021/acsomega.5c10898

Source records

crossref · retrieved 2026-09-26T06:29:32.005Z