Bioisosteric Replacement of Amides with 1,2,3-Triazoles Improves Dopamine D4 Receptor Ligand Pharmacokinetics.

Alkhatib M, Jakobs FM, Hanson JN, Nilson AN, Moritz AE, Li T, Faibille AB, Bourn LA, Ramdhan PA, Ricchezza J, Jordan S, Panasis D, Nguyen N, Kasarla N, Wang B, Garcia SS, Saez J, Paule J, Lee CB, Rais R, Slusher BS, Sibley DR, Li C, Keck TM, Boateng CA.

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DOI: 10.1021/acsptsci.5c00646
Published: 2026-01-09
Container: ACS Pharmacol Transl Sci
Publisher: Not recorded
Open access: yes

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Cite this work

BibTeX

@article{allodium:10.1021/acsptsci.5c00646,
  title = {Bioisosteric Replacement of Amides with 1,2,3-Triazoles Improves Dopamine D4 Receptor Ligand Pharmacokinetics.},
  author = {Alkhatib M and  Jakobs FM and  Hanson JN and  Nilson AN and  Moritz AE and  Li T and  Faibille AB and  Bourn LA and  Ramdhan PA and  Ricchezza J and  Jordan S and  Panasis D and  Nguyen N and  Kasarla N and  Wang B and  Garcia SS and  Saez J and  Paule J and  Lee CB and  Rais R and  Slusher BS and  Sibley DR and  Li C and  Keck TM and  Boateng CA.},
  year = {2026},
  journal = {ACS Pharmacol Transl Sci},
  doi = {10.1021/acsptsci.5c00646},
  url = {https://doi.org/10.1021/acsptsci.5c00646}
}

RIS

TY  - JOUR
TI  - Bioisosteric Replacement of Amides with 1,2,3-Triazoles Improves Dopamine D4 Receptor Ligand Pharmacokinetics.
AU  - Alkhatib M
AU  -  Jakobs FM
AU  -  Hanson JN
AU  -  Nilson AN
AU  -  Moritz AE
AU  -  Li T
AU  -  Faibille AB
AU  -  Bourn LA
AU  -  Ramdhan PA
AU  -  Ricchezza J
AU  -  Jordan S
AU  -  Panasis D
AU  -  Nguyen N
AU  -  Kasarla N
AU  -  Wang B
AU  -  Garcia SS
AU  -  Saez J
AU  -  Paule J
AU  -  Lee CB
AU  -  Rais R
AU  -  Slusher BS
AU  -  Sibley DR
AU  -  Li C
AU  -  Keck TM
AU  -  Boateng CA.
PY  - 2026
JO  - ACS Pharmacol Transl Sci
DO  - 10.1021/acsptsci.5c00646
UR  - https://doi.org/10.1021/acsptsci.5c00646
ER  -

APA

M, A., FM, J., JN, H., AN, N., AE, M., T, L., AB, F., LA, B., PA, R., J, R., S, J., D, P., N, N., N, K., B, W., SS, G., J, S., J, P., CB, L., R, R., BS, S., DR, S., C, L., TM, K., & CA., B. (2026). Bioisosteric Replacement of Amides with 1,2,3-Triazoles Improves Dopamine D4 Receptor Ligand Pharmacokinetics.. ACS Pharmacol Transl Sci. https://doi.org/10.1021/acsptsci.5c00646

Source records

europe-pmc · retrieved 2026-09-27T11:50:53.366Z