Local Ionic Conditions Modulate the Aggregation Propensity and Influence the Structural Polymorphism of α-Synuclein.

Zacharopoulou M, Seetaloo N, Ross J, Stephens AD, Fusco G, McCoy TM, Dai W, Mela I, Fernandez-Villegas A, Martel A, Routh AF, De Simone A, Phillips JJ, Kaminski Schierle GS

Open source

DOI: 10.1021/jacs.4c13473
Published: 2025 Apr 23
Container: Journal of the American Chemical Society
Publisher: Not recorded
Open access: yes

Credibility signals

limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
supportingOpen access status: Normalized open-access status: open. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1021/jacs.4c13473,
  title = {Local Ionic Conditions Modulate the Aggregation Propensity and Influence the Structural Polymorphism of α-Synuclein.},
  author = {Zacharopoulou M and Seetaloo N and Ross J and Stephens AD and Fusco G and McCoy TM and Dai W and Mela I and Fernandez-Villegas A and Martel A and Routh AF and De Simone A and Phillips JJ and Kaminski Schierle GS},
  year = {2025},
  journal = {Journal of the American Chemical Society},
  doi = {10.1021/jacs.4c13473},
  url = {https://doi.org/10.1021/jacs.4c13473}
}

RIS

TY  - JOUR
TI  - Local Ionic Conditions Modulate the Aggregation Propensity and Influence the Structural Polymorphism of α-Synuclein.
AU  - Zacharopoulou M
AU  - Seetaloo N
AU  - Ross J
AU  - Stephens AD
AU  - Fusco G
AU  - McCoy TM
AU  - Dai W
AU  - Mela I
AU  - Fernandez-Villegas A
AU  - Martel A
AU  - Routh AF
AU  - De Simone A
AU  - Phillips JJ
AU  - Kaminski Schierle GS
PY  - 2025
JO  - Journal of the American Chemical Society
DO  - 10.1021/jacs.4c13473
UR  - https://doi.org/10.1021/jacs.4c13473
ER  -

APA

M, Z., N, S., J, R., AD, S., G, F., TM, M., W, D., I, M., A, F., A, M., AF, R., A, D. S., JJ, P., & GS, K. S. (2025). Local Ionic Conditions Modulate the Aggregation Propensity and Influence the Structural Polymorphism of α-Synuclein.. Journal of the American Chemical Society. https://doi.org/10.1021/jacs.4c13473

Source records

pubmed · retrieved 2026-09-26T18:45:50.912Z