JAK2V617F reprograms Hypoxia Inducible Factor-1 to induce a non-canonical hypoxia regulon in myeloproliferative neoplasms.

Kealy D, Ellerington R, Bansal S, Medeiros JJF, Hawley CA, Zeng AGX, Lukaszonek J, West KA, Sinha AD, Caalim G, Gawne RT, Pope J, Ferreira BL, Blacknell NM, Drylie B, Chatzigerou J, Khoo HM, Wilkinson AC, Fielding AK, Wang G, Psaila B, Kent DG, Hitchcock IS, Holding AN, Mason AS, Gupta V, Dick JE, Bridge KS

Open source

DOI
10.1038/s41375-025-02843-9
Published
2026 Mar
Container
Leukemia
Publisher
Not recorded
Open access
yes

Credibility signals

limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

Cite this work

BibTeX

@article{allodium:10.1038/s41375-025-02843-9,
  title = {JAK2V617F reprograms Hypoxia Inducible Factor-1 to induce a non-canonical hypoxia regulon in myeloproliferative neoplasms.},
  author = {Kealy D and Ellerington R and Bansal S and Medeiros JJF and Hawley CA and Zeng AGX and Lukaszonek J and West KA and Sinha AD and Caalim G and Gawne RT and Pope J and Ferreira BL and Blacknell NM and Drylie B and Chatzigerou J and Khoo HM and Wilkinson AC and Fielding AK and Wang G and Psaila B and Kent DG and Hitchcock IS and Holding AN and Mason AS and Gupta V and Dick JE and Bridge KS},
  year = {2026},
  journal = {Leukemia},
  doi = {10.1038/s41375-025-02843-9},
  url = {https://doi.org/10.1038/s41375-025-02843-9}
}

RIS

TY  - JOUR
TI  - JAK2V617F reprograms Hypoxia Inducible Factor-1 to induce a non-canonical hypoxia regulon in myeloproliferative neoplasms.
AU  - Kealy D
AU  - Ellerington R
AU  - Bansal S
AU  - Medeiros JJF
AU  - Hawley CA
AU  - Zeng AGX
AU  - Lukaszonek J
AU  - West KA
AU  - Sinha AD
AU  - Caalim G
AU  - Gawne RT
AU  - Pope J
AU  - Ferreira BL
AU  - Blacknell NM
AU  - Drylie B
AU  - Chatzigerou J
AU  - Khoo HM
AU  - Wilkinson AC
AU  - Fielding AK
AU  - Wang G
AU  - Psaila B
AU  - Kent DG
AU  - Hitchcock IS
AU  - Holding AN
AU  - Mason AS
AU  - Gupta V
AU  - Dick JE
AU  - Bridge KS
PY  - 2026
JO  - Leukemia
DO  - 10.1038/s41375-025-02843-9
UR  - https://doi.org/10.1038/s41375-025-02843-9
ER  - 

APA

D, K., R, E., S, B., JJF, M., CA, H., AGX, Z., J, L., KA, W., AD, S., G, C., RT, G., J, P., BL, F., NM, B., B, D., J, C., HM, K., AC, W., AK, F., G, W., B, P., DG, K., IS, H., AN, H., AS, M., V, G., JE, D., & KS, B. (2026). JAK2V617F reprograms Hypoxia Inducible Factor-1 to induce a non-canonical hypoxia regulon in myeloproliferative neoplasms.. Leukemia. https://doi.org/10.1038/s41375-025-02843-9

Source records