Spatial remodeling of bone marrow architecture defines tissue-state signatures of disease activity and therapeutic response in myelodysplastic neoplasms

Ryan Nachman, Aleksandra Kopacz, Caitlin Unkenholz, Jian Chai, Arvin Ruiz, Itzel Valencia, Jeanne Jiang, Fabio Socciarelli, Jiwoon Park, Christopher E. Mason, Ling Zhang, David Sallman, Gail J. Roboz, Pinkal Desai, Justin Kaner, Joshua Fein, Monica Guzman, Neal Lindeman, Amy Chadburn, Madhu Ouseph, Paul Simonson, Julia Geyer, Giorgio Inghirami, Shahin Rafii, David Redmond, Sanjay S. Patel

Open source

DOI
10.1038/s41375-026-03029-7
Published
2026-06-30
Container
Leukemia
Publisher
Springer Science and Business Media LLC
Open access
unknown

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BibTeX

@article{allodium:10.1038/s41375-026-03029-7,
  title = {Spatial remodeling of bone marrow architecture defines tissue-state signatures of disease activity and therapeutic response in myelodysplastic neoplasms},
  author = {Ryan Nachman and Aleksandra Kopacz and Caitlin Unkenholz and Jian Chai and Arvin Ruiz and Itzel Valencia and Jeanne Jiang and Fabio Socciarelli and Jiwoon Park and Christopher E. Mason and Ling Zhang and David Sallman and Gail J. Roboz and Pinkal Desai and Justin Kaner and Joshua Fein and Monica Guzman and Neal Lindeman and Amy Chadburn and Madhu Ouseph and Paul Simonson and Julia Geyer and Giorgio Inghirami and Shahin Rafii and David Redmond and Sanjay S. Patel},
  year = {2026},
  journal = {Leukemia},
  doi = {10.1038/s41375-026-03029-7},
  url = {https://doi.org/10.1038/s41375-026-03029-7}
}

RIS

TY  - JOUR
TI  - Spatial remodeling of bone marrow architecture defines tissue-state signatures of disease activity and therapeutic response in myelodysplastic neoplasms
AU  - Ryan Nachman
AU  - Aleksandra Kopacz
AU  - Caitlin Unkenholz
AU  - Jian Chai
AU  - Arvin Ruiz
AU  - Itzel Valencia
AU  - Jeanne Jiang
AU  - Fabio Socciarelli
AU  - Jiwoon Park
AU  - Christopher E. Mason
AU  - Ling Zhang
AU  - David Sallman
AU  - Gail J. Roboz
AU  - Pinkal Desai
AU  - Justin Kaner
AU  - Joshua Fein
AU  - Monica Guzman
AU  - Neal Lindeman
AU  - Amy Chadburn
AU  - Madhu Ouseph
AU  - Paul Simonson
AU  - Julia Geyer
AU  - Giorgio Inghirami
AU  - Shahin Rafii
AU  - David Redmond
AU  - Sanjay S. Patel
PY  - 2026
JO  - Leukemia
DO  - 10.1038/s41375-026-03029-7
UR  - https://doi.org/10.1038/s41375-026-03029-7
ER  - 

APA

Nachman, R., Kopacz, A., Unkenholz, C., Chai, J., Ruiz, A., Valencia, I., Jiang, J., Socciarelli, F., Park, J., Mason, C. E., Zhang, L., Sallman, D., Roboz, G. J., Desai, P., Kaner, J., Fein, J., Guzman, M., Lindeman, N., Chadburn, A., Ouseph, M., Simonson, P., Geyer, J., Inghirami, G., Rafii, S., Redmond, D., & Patel, S. S. (2026). Spatial remodeling of bone marrow architecture defines tissue-state signatures of disease activity and therapeutic response in myelodysplastic neoplasms. Leukemia. https://doi.org/10.1038/s41375-026-03029-7

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