Targeting NFATc1-regulated MTHFD2 one-carbon metabolism to suppress sustained T-cell-mediated inflammation in rheumatoid arthritis.

Manolakou T, Shen J, Boddul S, Samiotaki M, Panagias MA, Sentis G, Silva TA, Argyriou A, Nikolopoulos D, Sanjiv K, Chemin K, Wermeling F, Henriksson M, Slipicevic A, Jakobsson PJ, Chatzidionysiou K, Helleday T

Open source

DOI
10.1038/s41392-026-02752-y
Published
2026 Jun 10
Container
Signal transduction and targeted therapy
Publisher
Not recorded
Open access
yes

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BibTeX

@article{allodium:10.1038/s41392-026-02752-y,
  title = {Targeting NFATc1-regulated MTHFD2 one-carbon metabolism to suppress sustained T-cell-mediated inflammation in rheumatoid arthritis.},
  author = {Manolakou T and Shen J and Boddul S and Samiotaki M and Panagias MA and Sentis G and Silva TA and Argyriou A and Nikolopoulos D and Sanjiv K and Chemin K and Wermeling F and Henriksson M and Slipicevic A and Jakobsson PJ and Chatzidionysiou K and Helleday T},
  year = {2026},
  journal = {Signal transduction and targeted therapy},
  doi = {10.1038/s41392-026-02752-y},
  url = {https://doi.org/10.1038/s41392-026-02752-y}
}

RIS

TY  - JOUR
TI  - Targeting NFATc1-regulated MTHFD2 one-carbon metabolism to suppress sustained T-cell-mediated inflammation in rheumatoid arthritis.
AU  - Manolakou T
AU  - Shen J
AU  - Boddul S
AU  - Samiotaki M
AU  - Panagias MA
AU  - Sentis G
AU  - Silva TA
AU  - Argyriou A
AU  - Nikolopoulos D
AU  - Sanjiv K
AU  - Chemin K
AU  - Wermeling F
AU  - Henriksson M
AU  - Slipicevic A
AU  - Jakobsson PJ
AU  - Chatzidionysiou K
AU  - Helleday T
PY  - 2026
JO  - Signal transduction and targeted therapy
DO  - 10.1038/s41392-026-02752-y
UR  - https://doi.org/10.1038/s41392-026-02752-y
ER  - 

APA

T, M., J, S., S, B., M, S., MA, P., G, S., TA, S., A, A., D, N., K, S., K, C., F, W., M, H., A, S., PJ, J., K, C., & T, H. (2026). Targeting NFATc1-regulated MTHFD2 one-carbon metabolism to suppress sustained T-cell-mediated inflammation in rheumatoid arthritis.. Signal transduction and targeted therapy. https://doi.org/10.1038/s41392-026-02752-y

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