PRMT5 inhibition impairs Fanconi Anemia pathway-mediated homologous recombination and enhances the antitumor efficacy of Temozolomide in glioblastoma.

Onishi S, Jayamohan S, Chowdhury A, Rivas S, Otani Y, Ertekin C, Bryant JP, Murphy SA, Rivera-Caraballo KA, Walbridge S, Sisay B, Maric D, Elkahloun A, Johnson K, Brown DA, Heiss JD, Shah AH, Lee TJ, Kumbar SG, Yoo JY, Brenner AJ, Kaur B, Sareddy GR, Banasavadi-Siddegowda YK

Open source

DOI
10.1038/s41419-026-08739-5
Published
2026 Apr 15
Container
Cell death & disease
Publisher
Not recorded
Open access
yes

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BibTeX

@article{allodium:10.1038/s41419-026-08739-5,
  title = {PRMT5 inhibition impairs Fanconi Anemia pathway-mediated homologous recombination and enhances the antitumor efficacy of Temozolomide in glioblastoma.},
  author = {Onishi S and Jayamohan S and Chowdhury A and Rivas S and Otani Y and Ertekin C and Bryant JP and Murphy SA and Rivera-Caraballo KA and Walbridge S and Sisay B and Maric D and Elkahloun A and Johnson K and Brown DA and Heiss JD and Shah AH and Lee TJ and Kumbar SG and Yoo JY and Brenner AJ and Kaur B and Sareddy GR and Banasavadi-Siddegowda YK},
  year = {2026},
  journal = {Cell death \& disease},
  doi = {10.1038/s41419-026-08739-5},
  url = {https://doi.org/10.1038/s41419-026-08739-5}
}

RIS

TY  - JOUR
TI  - PRMT5 inhibition impairs Fanconi Anemia pathway-mediated homologous recombination and enhances the antitumor efficacy of Temozolomide in glioblastoma.
AU  - Onishi S
AU  - Jayamohan S
AU  - Chowdhury A
AU  - Rivas S
AU  - Otani Y
AU  - Ertekin C
AU  - Bryant JP
AU  - Murphy SA
AU  - Rivera-Caraballo KA
AU  - Walbridge S
AU  - Sisay B
AU  - Maric D
AU  - Elkahloun A
AU  - Johnson K
AU  - Brown DA
AU  - Heiss JD
AU  - Shah AH
AU  - Lee TJ
AU  - Kumbar SG
AU  - Yoo JY
AU  - Brenner AJ
AU  - Kaur B
AU  - Sareddy GR
AU  - Banasavadi-Siddegowda YK
PY  - 2026
JO  - Cell death & disease
DO  - 10.1038/s41419-026-08739-5
UR  - https://doi.org/10.1038/s41419-026-08739-5
ER  - 

APA

S, O., S, J., A, C., S, R., Y, O., C, E., JP, B., SA, M., KA, R., S, W., B, S., D, M., A, E., K, J., DA, B., JD, H., AH, S., TJ, L., SG, K., JY, Y., AJ, B., B, K., GR, S., & YK, B. (2026). PRMT5 inhibition impairs Fanconi Anemia pathway-mediated homologous recombination and enhances the antitumor efficacy of Temozolomide in glioblastoma.. Cell death & disease. https://doi.org/10.1038/s41419-026-08739-5

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