Mitochondria-targeted metformin analogs activate the ER stress-unfolded protein response pathway to drive apoptosis in pancreatic cancer.

Poimenidou M, Bobek JM, Drouillard D, Harris T, Solis E, Darnell C, McAllister D, Keyes RF, Ishihara-Aoki M, Aoki K, Sahoo D, Kalyanaraman B, Smith BC, Dwinell MB

Open source

DOI
10.1038/s41419-026-08859-y
Published
2026 May 22
Container
Cell death & disease
Publisher
Not recorded
Open access
yes

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BibTeX

@article{allodium:10.1038/s41419-026-08859-y,
  title = {Mitochondria-targeted metformin analogs activate the ER stress-unfolded protein response pathway to drive apoptosis in pancreatic cancer.},
  author = {Poimenidou M and Bobek JM and Drouillard D and Harris T and Solis E and Darnell C and McAllister D and Keyes RF and Ishihara-Aoki M and Aoki K and Sahoo D and Kalyanaraman B and Smith BC and Dwinell MB},
  year = {2026},
  journal = {Cell death \& disease},
  doi = {10.1038/s41419-026-08859-y},
  url = {https://doi.org/10.1038/s41419-026-08859-y}
}

RIS

TY  - JOUR
TI  - Mitochondria-targeted metformin analogs activate the ER stress-unfolded protein response pathway to drive apoptosis in pancreatic cancer.
AU  - Poimenidou M
AU  - Bobek JM
AU  - Drouillard D
AU  - Harris T
AU  - Solis E
AU  - Darnell C
AU  - McAllister D
AU  - Keyes RF
AU  - Ishihara-Aoki M
AU  - Aoki K
AU  - Sahoo D
AU  - Kalyanaraman B
AU  - Smith BC
AU  - Dwinell MB
PY  - 2026
JO  - Cell death & disease
DO  - 10.1038/s41419-026-08859-y
UR  - https://doi.org/10.1038/s41419-026-08859-y
ER  - 

APA

M, P., JM, B., D, D., T, H., E, S., C, D., D, M., RF, K., M, I., K, A., D, S., B, K., BC, S., & MB, D. (2026). Mitochondria-targeted metformin analogs activate the ER stress-unfolded protein response pathway to drive apoptosis in pancreatic cancer.. Cell death & disease. https://doi.org/10.1038/s41419-026-08859-y

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