Rational design of a JAK1-selective siRNA inhibitor for the modulation of autoimmunity in the skin.

Tang Q, Fakih HH, Zain Ui Abideen M, Hildebrand SR, Afshari K, Gross KY, Sousa J, Maebius AS, Bartholdy C, Søgaard PP, Jackerott M, Hariharan V, Summers A, Fan X, Okamura K, Monopoli KR, Cooper DA, Echeverria D, Bramato B, McHugh N, Furgal RC, Dresser K, Winter SJ, Biscans A, Chuprin J, Haddadi NS, Sherman S, Yıldız-Altay Ü, Rashighi M, Richmond JM, Bouix-Peter C, Blanchard C, Clauss A, Alterman JF, Khvorova A, Harris JE

Open source

DOI: 10.1038/s41467-023-42714-4
Published: 2023 Nov 4
Container: Nature communications
Publisher: Not recorded
Open access: yes

Credibility signals

limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
supportingOpen access status: Normalized open-access status: open. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1038/s41467-023-42714-4,
  title = {Rational design of a JAK1-selective siRNA inhibitor for the modulation of autoimmunity in the skin.},
  author = {Tang Q and Fakih HH and Zain Ui Abideen M and Hildebrand SR and Afshari K and Gross KY and Sousa J and Maebius AS and Bartholdy C and Søgaard PP and Jackerott M and Hariharan V and Summers A and Fan X and Okamura K and Monopoli KR and Cooper DA and Echeverria D and Bramato B and McHugh N and Furgal RC and Dresser K and Winter SJ and Biscans A and Chuprin J and Haddadi NS and Sherman S and Yıldız-Altay Ü and Rashighi M and Richmond JM and Bouix-Peter C and Blanchard C and Clauss A and Alterman JF and Khvorova A and Harris JE},
  year = {2023},
  journal = {Nature communications},
  doi = {10.1038/s41467-023-42714-4},
  url = {https://doi.org/10.1038/s41467-023-42714-4}
}

RIS

TY  - JOUR
TI  - Rational design of a JAK1-selective siRNA inhibitor for the modulation of autoimmunity in the skin.
AU  - Tang Q
AU  - Fakih HH
AU  - Zain Ui Abideen M
AU  - Hildebrand SR
AU  - Afshari K
AU  - Gross KY
AU  - Sousa J
AU  - Maebius AS
AU  - Bartholdy C
AU  - Søgaard PP
AU  - Jackerott M
AU  - Hariharan V
AU  - Summers A
AU  - Fan X
AU  - Okamura K
AU  - Monopoli KR
AU  - Cooper DA
AU  - Echeverria D
AU  - Bramato B
AU  - McHugh N
AU  - Furgal RC
AU  - Dresser K
AU  - Winter SJ
AU  - Biscans A
AU  - Chuprin J
AU  - Haddadi NS
AU  - Sherman S
AU  - Yıldız-Altay Ü
AU  - Rashighi M
AU  - Richmond JM
AU  - Bouix-Peter C
AU  - Blanchard C
AU  - Clauss A
AU  - Alterman JF
AU  - Khvorova A
AU  - Harris JE
PY  - 2023
JO  - Nature communications
DO  - 10.1038/s41467-023-42714-4
UR  - https://doi.org/10.1038/s41467-023-42714-4
ER  -

APA

Q, T., HH, F., M, Z. U. A., SR, H., K, A., KY, G., J, S., AS, M., C, B., PP, S., M, J., V, H., A, S., X, F., K, O., KR, M., DA, C., D, E., B, B., N, M., RC, F., K, D., SJ, W., A, B., J, C., NS, H., S, S., Ü, Y., M, R., JM, R., C, B., C, B., A, C., JF, A., A, K., & JE, H. (2023). Rational design of a JAK1-selective siRNA inhibitor for the modulation of autoimmunity in the skin.. Nature communications. https://doi.org/10.1038/s41467-023-42714-4

Source records

pubmed · retrieved 2026-09-27T08:18:44.633Z