Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications

Rosalie B. T. M. Sterenborg, Inga Steinbrenner, Yong Li, Melissa N. Bujnis, Tatsuhiko Naito, Eirini Marouli, Tessel E. Galesloot, Oladapo Babajide, Laura Andreasen, Arne Astrup, Bjørn Olav Åsvold, Stefania Bandinelli, Marian Beekman, John P. Beilby, Jette Bork-Jensen, Thibaud Boutin, Jennifer A. Brody, Suzanne J. Brown, Ben Brumpton, Purdey J. Campbell, Anne R. Cappola, Graziano Ceresini, Layal Chaker, Daniel I. Chasman, Maria Pina Concas, Rodrigo Coutinho de Almeida, Simone M. Cross, Francesco Cucca, Ian J. Deary, Alisa Devedzic Kjaergaard, Justin B. Echouffo Tcheugui, Christina Ellervik, Johan G. Eriksson, Luigi Ferrucci, Jan Freudenberg, Unknown, Unknown, Christian Fuchsberger, Christian Gieger, Franco Giulianini, Martin Gögele, Sarah E. Graham, Niels Grarup, Ivana Gunjača, Torben Hansen, Barbara N. Harding, Sarah E. Harris, Stig Haunsø, Caroline Hayward, Jennie Hui, Till Ittermann, J. Wouter Jukema, Eero Kajantie, Jørgen K. Kanters, Line L. Kårhus, Lambertus A. L. M. Kiemeney, Margreet Kloppenburg, Brigitte Kühnel, Jari Lahti, Claudia Langenberg, Bruno Lapauw, Graham Leese, Shuo Li, David C. M. Liewald, Allan Linneberg, Jesus V. T. Lominchar, Jian’an Luan, Nicholas G. Martin, Antonela Matana, Marcel E. Meima, Thomas Meitinger, Ingrid Meulenbelt, Braxton D. Mitchell, Line T. Møllehave, Samia Mora, Silvia Naitza, Matthias Nauck, Romana T. Netea-Maier, Raymond Noordam, Casia Nursyifa, Yukinori Okada, Stefano Onano, Areti Papadopoulou, Colin N. A. Palmer, Cristian Pattaro, Oluf Pedersen, Annette Peters, Maik Pietzner, Ozren Polašek, Peter P. Pramstaller, Bruce M. Psaty, Ante Punda, Debashree Ray, Paul Redmond, J. Brent Richards, Paul M. Ridker, Tom C. Russ, Kathleen A. Ryan, Morten Salling Olesen, Ulla T. Schultheiss, Elizabeth Selvin, Moneeza K. Siddiqui, Carlo Sidore, P. Eline Slagboom, Thorkild I. A. Sørensen, Enrique Soto-Pedre, Tim D. Spector, Beatrice Spedicati, Sundararajan Srinivasan, John M. Starr, David J. Stott, Toshiko Tanaka, Vesela Torlak, Stella Trompet, Johanna Tuhkanen, André G. Uitterlinden, Erik B. van den Akker, Tibbert van den Eynde, Melanie M. van der Klauw, Diana van Heemst, Charlotte Verroken, W. Edward Visser, Dina Vojinovic, Henry Völzke, Melanie Waldenberger, John P. Walsh, Nicholas J. Wareham, Stefan Weiss, Cristen J. Willer, Scott G. Wilson, Bruce H. R. Wolffenbuttel, Hanneke J. C. M. Wouters, Margaret J. Wright, Qiong Yang, Tatijana Zemunik, Wei Zhou, Gu Zhu, Sebastian Zöllner, Johannes W. A. Smit, Robin P. Peeters, Anna Köttgen, Alexander Teumer, Marco Medici

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DOI
10.1038/s41467-024-44701-9
Published
2024-01-30
Container
Nature Communications
Publisher
Springer Science and Business Media LLC
Open access
unknown

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BibTeX

@article{allodium:10.1038/s41467-024-44701-9,
  title = {Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications},
  author = {Rosalie B. T. M. Sterenborg and Inga Steinbrenner and Yong Li and Melissa N. Bujnis and Tatsuhiko Naito and Eirini Marouli and Tessel E. Galesloot and Oladapo Babajide and Laura Andreasen and Arne Astrup and Bjørn Olav Åsvold and Stefania Bandinelli and Marian Beekman and John P. Beilby and Jette Bork-Jensen and Thibaud Boutin and Jennifer A. Brody and Suzanne J. Brown and Ben Brumpton and Purdey J. Campbell and Anne R. Cappola and Graziano Ceresini and Layal Chaker and Daniel I. Chasman and Maria Pina Concas and Rodrigo Coutinho de Almeida and Simone M. Cross and Francesco Cucca and Ian J. Deary and Alisa Devedzic Kjaergaard and Justin B. Echouffo Tcheugui and Christina Ellervik and Johan G. Eriksson and Luigi Ferrucci and Jan Freudenberg and Unknown and Unknown and Christian Fuchsberger and Christian Gieger and Franco Giulianini and Martin Gögele and Sarah E. Graham and Niels Grarup and Ivana Gunjača and Torben Hansen and Barbara N. Harding and Sarah E. Harris and Stig Haunsø and Caroline Hayward and Jennie Hui and Till Ittermann and J. Wouter Jukema and Eero Kajantie and Jørgen K. Kanters and Line L. Kårhus and Lambertus A. L. M. Kiemeney and Margreet Kloppenburg and Brigitte Kühnel and Jari Lahti and Claudia Langenberg and Bruno Lapauw and Graham Leese and Shuo Li and David C. M. Liewald and Allan Linneberg and Jesus V. T. Lominchar and Jian’an Luan and Nicholas G. Martin and Antonela Matana and Marcel E. Meima and Thomas Meitinger and Ingrid Meulenbelt and Braxton D. Mitchell and Line T. Møllehave and Samia Mora and Silvia Naitza and Matthias Nauck and Romana T. Netea-Maier and Raymond Noordam and Casia Nursyifa and Yukinori Okada and Stefano Onano and Areti Papadopoulou and Colin N. A. Palmer and Cristian Pattaro and Oluf Pedersen and Annette Peters and Maik Pietzner and Ozren Polašek and Peter P. Pramstaller and Bruce M. Psaty and Ante Punda and Debashree Ray and Paul Redmond and J. Brent Richards and Paul M. Ridker and Tom C. Russ and Kathleen A. Ryan and Morten Salling Olesen and Ulla T. Schultheiss and Elizabeth Selvin and Moneeza K. Siddiqui and Carlo Sidore and P. Eline Slagboom and Thorkild I. A. Sørensen and Enrique Soto-Pedre and Tim D. Spector and Beatrice Spedicati and Sundararajan Srinivasan and John M. Starr and David J. Stott and Toshiko Tanaka and Vesela Torlak and Stella Trompet and Johanna Tuhkanen and André G. Uitterlinden and Erik B. van den Akker and Tibbert van den Eynde and Melanie M. van der Klauw and Diana van Heemst and Charlotte Verroken and W. Edward Visser and Dina Vojinovic and Henry Völzke and Melanie Waldenberger and John P. Walsh and Nicholas J. Wareham and Stefan Weiss and Cristen J. Willer and Scott G. Wilson and Bruce H. R. Wolffenbuttel and Hanneke J. C. M. Wouters and Margaret J. Wright and Qiong Yang and Tatijana Zemunik and Wei Zhou and Gu Zhu and Sebastian Zöllner and Johannes W. A. Smit and Robin P. Peeters and Anna Köttgen and Alexander Teumer and Marco Medici},
  year = {2024},
  journal = {Nature Communications},
  doi = {10.1038/s41467-024-44701-9},
  url = {https://doi.org/10.1038/s41467-024-44701-9}
}

RIS

TY  - JOUR
TI  - Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications
AU  - Rosalie B. T. M. Sterenborg
AU  - Inga Steinbrenner
AU  - Yong Li
AU  - Melissa N. Bujnis
AU  - Tatsuhiko Naito
AU  - Eirini Marouli
AU  - Tessel E. Galesloot
AU  - Oladapo Babajide
AU  - Laura Andreasen
AU  - Arne Astrup
AU  - Bjørn Olav Åsvold
AU  - Stefania Bandinelli
AU  - Marian Beekman
AU  - John P. Beilby
AU  - Jette Bork-Jensen
AU  - Thibaud Boutin
AU  - Jennifer A. Brody
AU  - Suzanne J. Brown
AU  - Ben Brumpton
AU  - Purdey J. Campbell
AU  - Anne R. Cappola
AU  - Graziano Ceresini
AU  - Layal Chaker
AU  - Daniel I. Chasman
AU  - Maria Pina Concas
AU  - Rodrigo Coutinho de Almeida
AU  - Simone M. Cross
AU  - Francesco Cucca
AU  - Ian J. Deary
AU  - Alisa Devedzic Kjaergaard
AU  - Justin B. Echouffo Tcheugui
AU  - Christina Ellervik
AU  - Johan G. Eriksson
AU  - Luigi Ferrucci
AU  - Jan Freudenberg
AU  - Unknown
AU  - Unknown
AU  - Christian Fuchsberger
AU  - Christian Gieger
AU  - Franco Giulianini
AU  - Martin Gögele
AU  - Sarah E. Graham
AU  - Niels Grarup
AU  - Ivana Gunjača
AU  - Torben Hansen
AU  - Barbara N. Harding
AU  - Sarah E. Harris
AU  - Stig Haunsø
AU  - Caroline Hayward
AU  - Jennie Hui
AU  - Till Ittermann
AU  - J. Wouter Jukema
AU  - Eero Kajantie
AU  - Jørgen K. Kanters
AU  - Line L. Kårhus
AU  - Lambertus A. L. M. Kiemeney
AU  - Margreet Kloppenburg
AU  - Brigitte Kühnel
AU  - Jari Lahti
AU  - Claudia Langenberg
AU  - Bruno Lapauw
AU  - Graham Leese
AU  - Shuo Li
AU  - David C. M. Liewald
AU  - Allan Linneberg
AU  - Jesus V. T. Lominchar
AU  - Jian’an Luan
AU  - Nicholas G. Martin
AU  - Antonela Matana
AU  - Marcel E. Meima
AU  - Thomas Meitinger
AU  - Ingrid Meulenbelt
AU  - Braxton D. Mitchell
AU  - Line T. Møllehave
AU  - Samia Mora
AU  - Silvia Naitza
AU  - Matthias Nauck
AU  - Romana T. Netea-Maier
AU  - Raymond Noordam
AU  - Casia Nursyifa
AU  - Yukinori Okada
AU  - Stefano Onano
AU  - Areti Papadopoulou
AU  - Colin N. A. Palmer
AU  - Cristian Pattaro
AU  - Oluf Pedersen
AU  - Annette Peters
AU  - Maik Pietzner
AU  - Ozren Polašek
AU  - Peter P. Pramstaller
AU  - Bruce M. Psaty
AU  - Ante Punda
AU  - Debashree Ray
AU  - Paul Redmond
AU  - J. Brent Richards
AU  - Paul M. Ridker
AU  - Tom C. Russ
AU  - Kathleen A. Ryan
AU  - Morten Salling Olesen
AU  - Ulla T. Schultheiss
AU  - Elizabeth Selvin
AU  - Moneeza K. Siddiqui
AU  - Carlo Sidore
AU  - P. Eline Slagboom
AU  - Thorkild I. A. Sørensen
AU  - Enrique Soto-Pedre
AU  - Tim D. Spector
AU  - Beatrice Spedicati
AU  - Sundararajan Srinivasan
AU  - John M. Starr
AU  - David J. Stott
AU  - Toshiko Tanaka
AU  - Vesela Torlak
AU  - Stella Trompet
AU  - Johanna Tuhkanen
AU  - André G. Uitterlinden
AU  - Erik B. van den Akker
AU  - Tibbert van den Eynde
AU  - Melanie M. van der Klauw
AU  - Diana van Heemst
AU  - Charlotte Verroken
AU  - W. Edward Visser
AU  - Dina Vojinovic
AU  - Henry Völzke
AU  - Melanie Waldenberger
AU  - John P. Walsh
AU  - Nicholas J. Wareham
AU  - Stefan Weiss
AU  - Cristen J. Willer
AU  - Scott G. Wilson
AU  - Bruce H. R. Wolffenbuttel
AU  - Hanneke J. C. M. Wouters
AU  - Margaret J. Wright
AU  - Qiong Yang
AU  - Tatijana Zemunik
AU  - Wei Zhou
AU  - Gu Zhu
AU  - Sebastian Zöllner
AU  - Johannes W. A. Smit
AU  - Robin P. Peeters
AU  - Anna Köttgen
AU  - Alexander Teumer
AU  - Marco Medici
PY  - 2024
JO  - Nature Communications
DO  - 10.1038/s41467-024-44701-9
UR  - https://doi.org/10.1038/s41467-024-44701-9
ER  -

APA

Sterenborg, R. B. T. M., Steinbrenner, I., Li, Y., Bujnis, M. N., Naito, T., Marouli, E., Galesloot, T. E., Babajide, O., Andreasen, L., Astrup, A., Åsvold, B. O., Bandinelli, S., Beekman, M., Beilby, J. P., Bork-Jensen, J., Boutin, T., Brody, J. A., Brown, S. J., Brumpton, B., Campbell, P. J., Cappola, A. R., Ceresini, G., Chaker, L., Chasman, D. I., Concas, M. P., Almeida, R. C. D., Cross, S. M., Cucca, F., Deary, I. J., Kjaergaard, A. D., Tcheugui, J. B. E., Ellervik, C., Eriksson, J. G., Ferrucci, L., Freudenberg, J., Unknown, Unknown, Fuchsberger, C., Gieger, C., Giulianini, F., Gögele, M., Graham, S. E., Grarup, N., Gunjača, I., Hansen, T., Harding, B. N., Harris, S. E., Haunsø, S., Hayward, C., Hui, J., Ittermann, T., Jukema, J. W., Kajantie, E., Kanters, J. K., Kårhus, L. L., Kiemeney, L. A. L. M., Kloppenburg, M., Kühnel, B., Lahti, J., Langenberg, C., Lapauw, B., Leese, G., Li, S., Liewald, D. C. M., Linneberg, A., Lominchar, J. V. T., Luan, J., Martin, N. G., Matana, A., Meima, M. E., Meitinger, T., Meulenbelt, I., Mitchell, B. D., Møllehave, L. T., Mora, S., Naitza, S., Nauck, M., Netea-Maier, R. T., Noordam, R., Nursyifa, C., Okada, Y., Onano, S., Papadopoulou, A., Palmer, C. N. A., Pattaro, C., Pedersen, O., Peters, A., Pietzner, M., Polašek, O., Pramstaller, P. P., Psaty, B. M., Punda, A., Ray, D., Redmond, P., Richards, J. B., Ridker, P. M., Russ, T. C., Ryan, K. A., Olesen, M. S., Schultheiss, U. T., Selvin, E., Siddiqui, M. K., Sidore, C., Slagboom, P. E., Sørensen, T. I. A., Soto-Pedre, E., Spector, T. D., Spedicati, B., Srinivasan, S., Starr, J. M., Stott, D. J., Tanaka, T., Torlak, V., Trompet, S., Tuhkanen, J., Uitterlinden, A. G., Akker, E. B. V. D., Eynde, T. V. D., Klauw, M. M. V. D., Heemst, D. V., Verroken, C., Visser, W. E., Vojinovic, D., Völzke, H., Waldenberger, M., Walsh, J. P., Wareham, N. J., Weiss, S., Willer, C. J., Wilson, S. G., Wolffenbuttel, B. H. R., Wouters, H. J. C. M., Wright, M. J., Yang, Q., Zemunik, T., Zhou, W., Zhu, G., Zöllner, S., Smit, J. W. A., Peeters, R. P., Köttgen, A., Teumer, A., & Medici, M. (2024). Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications. Nature Communications. https://doi.org/10.1038/s41467-024-44701-9

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